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Species: Human Mouse

STAT3 is a Transcription Factor.

1. Targets and Regulators

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STAT3 targets

#TFTargetMode of RegulationReferences
(PMID)
1 STAT3 A2M Unknown 11466367
2 STAT3 ABCA1 Unknown 19783654
3 STAT3 AKAP12 Activation 22584896
4 STAT3 AKT1 Unknown 16007214
5 STAT3 AR Unknown 23906537
6 STAT3 BCL2 Activation 15184887; 15805299; 18839277; 19926637; 21435102; 22504301
7 STAT3 BCL2 Repression 22313388
8 STAT3 BCL2 Unknown 18320073; 20043094; 20446017; 21172343; 21344490; 21385902
9 STAT3 BCL2L1 Activation 11369651; 15184887; 15805299; 16651438; 17880940; 20069389; 21435102
10 STAT3 BCL2L1 Repression 20067773
11 STAT3 BCL2L1 Unknown 15469392; 16384639; 18222423; 18790750; 20654581; 21172343; 21344490
12 STAT3 BCL6 Activation 20228272; 23716595
13 STAT3 BIRC5 Activation 15184887; 16651438; 17880940; 19284568; 19880237
14 STAT3 BIRC5 Unknown 15469392; 20826784; 21344490
15 STAT3 CCL11 Activation 19265112
16 STAT3 CCL11 Unknown 20169197
17 STAT3 CCL2 Activation 24429361
18 STAT3 CCND1 Activation 16651438; 19880237; 19926637; 21435102; 22218594
19 STAT3 CCND1 Repression 19880237; 22313388
20 STAT3 CCND1 Unknown 12147685; 15469392; 16384639; 16510571; 18184402; 20332458; 21172343; 21344490
21 STAT3 CCND2 Unknown 12147685
22 STAT3 CCND3 Activation 15184887
23 STAT3 CD46 Activation 17699108
24 STAT3 CDH1 Unknown 18320073; 22205702
25 STAT3 CDK4 Activation 22218594
26 STAT3 CDKN1A Activation 10023678; 15286705
27 STAT3 CDKN1A Unknown 16923815; 18320073; 20654581
28 STAT3 CDKN1B Unknown 18320073
29 STAT3 CFB Activation 22169226
30 STAT3 CFLAR Unknown 18222423
31 STAT3 CHI3L1 Activation 21953450
32 STAT3 CISH Activation 14630083
33 STAT3 COPS5 Unknown 21689417
34 STAT3 CRP Activation 12667216; 20978825; 23361365
35 STAT3 CRP Unknown 18292576
36 STAT3 CSRP1 Activation 8621622
37 STAT3 CSRP1 Unknown 18292576
38 STAT3 CTGF Repression 21245987
39 STAT3 CXCL8 Unknown 17726017
40 STAT3 CYP19A1 Unknown 15072557
41 STAT3 CYR61 Unknown 22401280
42 STAT3 DDIT3 Repression 23288901
43 STAT3 DIRAS3 Unknown 23604529
44 STAT3 DNMT1 Activation 16861352; 21944426
45 STAT3 DNMT1 Unknown 19887607; 23604529
46 STAT3 EGFR Activation 21590492; 23504318
47 STAT3 EPAS1 Unknown 23991099
48 STAT3 ESR2 Activation 21546410
49 STAT3 ETV6 Activation 15229229
50 STAT3 F2R Activation 23504318
51 STAT3 FAAH Activation 12556536
52 STAT3 FAS Activation 15223310
53 STAT3 FAS Repression 16651438; 22313388
54 STAT3 FGF1 Repression 14673954
55 STAT3 FGF2 Activation 21418908; 23086340
56 STAT3 FGF2 Unknown 16540670
57 STAT3 FGG Activation 11460505
58 STAT3 FGL1 Unknown 19304666
59 STAT3 FLT3 Activation 16418395
60 STAT3 FOS Activation 12600988; 14737107; 17204573
61 STAT3 GAST Activation 20568281
62 STAT3 GAST Unknown 20949125
63 STAT3 GFAP Activation 21833841
64 STAT3 GFAP Unknown 11740937
65 STAT3 GREB1 Unknown 23056300
66 STAT3 HAMP Activation 18671304
67 STAT3 HAMP Unknown 16835372
68 STAT3 HGF Activation 12168776
69 STAT3 HGF Unknown 23954444
70 STAT3 HIF1A Activation 17597020; 18644974; 19265129
71 STAT3 HIF1A Unknown 23991099
72 STAT3 HMOX1 Activation 19129475
73 STAT3 HP Unknown 17645497
74 STAT3 HSPA4 Activation 19754877
75 STAT3 HSPB1 Activation 14715258
76 STAT3 ICAM1 Unknown 23690481; 8675499
77 STAT3 IFNAR1 Activation 18550668
78 STAT3 IFNG Repression 18616672
79 STAT3 IKBKE Activation 22330135
80 STAT3 IL10 Activation 12817009; 18765795
81 STAT3 IL10 Unknown 10903771; 15034082; 17404037; 18403020; 19124156
82 STAT3 IL11 Unknown 23224145
83 STAT3 IL1RN Activation 20032313
84 STAT3 IL2 Activation 18550668
85 STAT3 IL21 Activation 18209077
86 STAT3 IL2RA Unknown 10068671; 11368440; 24159173
87 STAT3 IL6 Activation 10391682; 18765795; 20930550; 22547075; 22927445
88 STAT3 IL6 Repression 18616672
89 STAT3 IL6 Unknown 22105366; 22363173
90 STAT3 IRF1 Activation 8647845
91 STAT3 IRF1 Unknown 10068671
92 STAT3 JAK2 Activation 17151100
93 STAT3 JAK2 Unknown 19783654
94 STAT3 JUNB Activation 17204573
95 STAT3 KLF11 Activation 18505768
96 STAT3 KRT17 Activation 21796151
97 STAT3 LCAT Unknown 12032172
98 STAT3 LEP Activation 18242580; 19492417
99 STAT3 LGALS3BP Repression 18594176
100 STAT3 LTBP1 Repression 22814105
101 STAT3 MCL1 Activation 15184887; 15805299; 16432172; 17880940; 19523441
102 STAT3 MCL1 Repression 22313388
103 STAT3 MCL1 Unknown 15469392; 16317687; 18790750; 19595668; 20654581; 22465052
104 STAT3 MDC1 Unknown 20804538
105 STAT3 MICA Repression 21257710; 23686482
106 STAT3 MMP1 Unknown 16205632; 17460772; 21410405
107 STAT3 MMP10 Unknown 16205632
108 STAT3 MMP14 Unknown 14673954
109 STAT3 MMP2 Activation 17533737; 19284568; 20069389
110 STAT3 MMP2 Repression 17533737
111 STAT3 MMP2 Unknown 16540670
112 STAT3 MMP3 Unknown 17460772; 23967200
113 STAT3 MMP7 Activation 18411043
114 STAT3 MMP7 Repression 20939893
115 STAT3 MMP9 Repression 20067773
116 STAT3 MUC1 Activation 17151127; 19578748; 21325207
117 STAT3 MUC4 Activation 18573283
118 STAT3 MUC4 Unknown 15485908
119 STAT3 MUC5B Unknown 15485908
120 STAT3 MYC Activation 15184887; 17204573; 19259613
121 STAT3 MYC Repression 20067773; 22317895
122 STAT3 MYC Unknown 10464281; 15469392; 18184402; 20654581
123 STAT3 MYD88 Unknown 12244150
124 STAT3 NANOG Activation 21689689
125 STAT3 NLK Unknown 15764709
126 STAT3 NME1 Activation 23583378
127 STAT3 NOX1 Unknown 19834108
128 STAT3 NOX4 Unknown 19834108
129 STAT3 NOX5 Activation 22348975
130 STAT3 NR2C2 Unknown 15764709
131 STAT3 OAS1 Repression 18550668
132 STAT3 OPRM1 Activation 15448191
133 STAT3 OSM Activation 10391682
134 STAT3 PAX3 Repression 19074888
135 STAT3 PGF Repression 23042533
136 STAT3 PHB Unknown 17324931
137 STAT3 PIAS3 Activation 14630083
138 STAT3 PIM1 Activation 22273698
139 STAT3 PIM1 Unknown 10068671
140 STAT3 POU2F1 Unknown 23172665
141 STAT3 PPARA Activation 24242046
142 STAT3 PRDM1 Activation 1702555
143 STAT3 PRDM1 Unknown 12953803
144 STAT3 PROS1 Unknown 16840717
145 STAT3 PSMB5 Activation 24627483
146 STAT3 PTEN Activation 22055460
147 STAT3 PTGS2 Activation 20145033
148 STAT3 PTGS2 Unknown 21172343
149 STAT3 PTPN13 Activation 24191246
150 STAT3 PTPN6 Repression 14630083; 16825495; 21792937
151 STAT3 PTPN6 Unknown 15870198
152 STAT3 ROR1 Unknown 20686606
153 STAT3 S100A11 Activation 24376686
154 STAT3 S1PR1 Activation 21102457
155 STAT3 SAA1 Unknown 16236134; 23391827
156 STAT3 SALL4 Activation 19151334
157 STAT3 SHH Activation 22554932
158 STAT3 SOCS1 Activation 14630083; 20003295; 20357037
159 STAT3 SOCS3 Activation 11788008; 15184887; 19332118; 20357037; 22179221
160 STAT3 SOCS3 Unknown 23335796
161 STAT3 STAT1 Activation 22693070
162 STAT3 STK11 Unknown 24913037
163 STAT3 STS Activation 21331591
164 STAT3 TERT Activation 20171193; 23158658
165 STAT3 TGFB1 Activation 16474852
166 STAT3 TIMP1 Activation 15161657
167 STAT3 TIMP1 Unknown 11918744; 15920698
168 STAT3 TNFRSF10B Repression 19351839
169 STAT3 TP53 Unknown 20043094
170 STAT3 TP63 Activation 18198175
171 STAT3 TRH Unknown 11134186
172 STAT3 TWIST1 Unknown 17909010
173 STAT3 TWIST1 Activation 23623921
174 STAT3 TWIST1 Unknown 17909010
175 STAT3 TWIST2 Unknown 17909010
176 STAT3 TYK2 Repression 18550668
177 STAT3 UCP2 Repression 21344490
178 STAT3 USP7 Repression 22750444
179 STAT3 VDR Repression 23424038
180 STAT3 VEGFA Unknown 23104276
181 STAT3 VEGFA Activation 11960372; 15735682; 17169602; 17533737; 19284568; 19880237; 21278793; 21418908
182 STAT3 VEGFA Repression 17533737; 19880237; 22313388
183 STAT3 VEGFA Unknown 12824281; 16540670; 16899623; 17937859; 18184402; 18320073; 19020709; 20043094; 21172343; 21344490; 21731766; 25101566
184 STAT3 VEGFB Unknown 16899623; 21731766
185 STAT3 ZFP36 Activation 21606497
Modularity measured by P value : 0.001

TFs that regulate STAT3

#TFTargetMode of RegulationReferences
(PMID)
1 BCL6 STAT3 Unknown 17951530
2 BRCA1 STAT3 Unknown 11163768
3 CEBPA STAT3 Unknown 24429361
4 HDAC1 STAT3 Unknown 18611949
5 HIC1 STAT3 Activation 24067369
6 HIF1A STAT3 Unknown 23991099
7 KAT5 STAT3 Repression 12551922
8 PIAS3 STAT3 Unknown 16098628
9 RELA STAT3 Unknown 25040843
10 SPI1 STAT3 Unknown 24429361
11 STAT1 STAT3 Unknown 22693070
12 TCF7L2 STAT3 Unknown 18602747
13 TP53 STAT3 Repression 11809683
14 ZNF382 STAT3 Repression 20682794

2. Other TFs that share targets with STAT3

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TFs that share targets with STAT3

*P values are calculated with hypergeometric test.
TF# of overlapped
target genes		P valueFDR
RELA 59 7.02e-66 5.11e-63
NFKB1 59 8.60e-66 5.69e-63
STAT1 30 1.08e-40 3.74e-38
SP1 49 3.61e-40 1.14e-37
JUN 30 3.18e-33 5.65e-31
TP53 25 6.92e-25 5.93e-23
HDAC1 20 8.60e-25 7.27e-23
ESR1 18 7.95e-22 5.26e-20
HIF1A 18 6.98e-21 4.34e-19
EGR1 18 2.09e-20 1.24e-18
PPARG 16 1.87e-19 1.05e-17
TFAP2A 16 3.08e-19 1.70e-17
BRCA1 15 5.69e-19 3.02e-17
CEBPB 15 2.20e-18 1.08e-16
SIRT1 14 8.66e-18 3.84e-16
FOS 14 1.51e-17 6.50e-16
STAT4 9 2.43e-17 1.02e-15
WT1 13 6.46e-16 2.36e-14
SP3 16 1.42e-15 4.96e-14
ETV4 10 1.52e-15 5.28e-14
KLF4 11 8.89e-15 2.81e-13
HDAC2 10 9.91e-15 3.12e-13
REL 9 5.13e-14 1.40e-12
EP300 12 1.10e-13 2.83e-12
ETS2 10 1.32e-13 3.35e-12
MYC 14 2.20e-13 5.36e-12
CREB1 13 4.01e-13 9.29e-12
E2F1 15 4.98e-13 1.13e-11
CEBPA 11 5.69e-13 1.28e-11
PGR 9 6.83e-13 1.52e-11
AR 13 1.81e-12 3.66e-11
SMAD3 9 2.70e-12 5.18e-11
PAX5 8 2.75e-12 5.26e-11
USF2 10 5.37e-12 9.87e-11
STAT5A 7 6.28e-12 1.14e-10
TWIST1 9 8.81e-12 1.55e-10
ATM 8 9.73e-12 1.69e-10
ETS1 12 1.15e-11 1.97e-10
ING4 7 1.17e-11 2.00e-10
ATF4 9 1.51e-11 2.52e-10
STAT6 9 2.49e-11 3.98e-10
EZH2 9 3.17e-11 4.94e-10
ZNF300 5 3.18e-11 4.94e-10
ABL1 6 5.07e-11 7.61e-10
HOXB7 6 5.07e-11 7.61e-10
VDR 9 1.76e-10 2.34e-09
JUND 8 2.24e-10 2.86e-09
YY1 11 3.16e-10 3.92e-09
CTNNB1 7 4.22e-10 5.04e-09
NR3C1 8 5.88e-10 6.65e-09
MTA1 7 1.11e-09 1.15e-08
SMAD4 7 1.49e-09 1.50e-08
TCF4 7 1.49e-09 1.50e-08
STAT5B 5 1.75e-09 1.71e-08
TBP 6 1.86e-09 1.80e-08
PARP1 7 1.97e-09 1.89e-08
USF1 9 2.82e-09 2.62e-08
FOXO3 6 4.25e-09 3.71e-08
RB1 7 4.29e-09 3.74e-08
SRF 7 4.29e-09 3.74e-08
GLI1 6 6.17e-09 5.21e-08
NFKBIA 6 6.17e-09 5.21e-08
HIPK2 5 7.75e-09 6.36e-08
ZFP36 5 7.75e-09 6.36e-08
IRF1 8 8.23e-09 6.70e-08
VHL 6 8.75e-09 7.06e-08
NPM1 5 1.41e-08 1.08e-07
E2F4 6 3.87e-08 2.58e-07
APC 5 3.88e-08 2.59e-07
HDAC3 6 4.99e-08 3.22e-07
HDGF 4 6.00e-08 3.77e-07
IFI16 4 6.00e-08 3.77e-07
SOX6 4 6.00e-08 3.77e-07
BCL6 6 8.06e-08 4.88e-07
NFYB 5 8.94e-08 5.27e-07
CREBBP 6 1.25e-07 7.01e-07
RUNX3 6 1.25e-07 7.01e-07
HOXA1 4 1.39e-07 7.71e-07
DNMT1 6 1.54e-07 8.45e-07
PTTG1 5 1.82e-07 9.71e-07
ATF2 6 2.29e-07 1.20e-06
FOXM1 5 2.50e-07 1.29e-06
GLI2 5 2.50e-07 1.29e-06
ELK1 5 4.47e-07 2.13e-06
KLF5 5 4.47e-07 2.13e-06
PML 5 4.47e-07 2.13e-06
RUNX2 5 4.47e-07 2.13e-06
XBP1 5 4.47e-07 2.13e-06
SMARCA4 4 4.95e-07 2.32e-06
SNAI2 5 5.83e-07 2.67e-06
ATF3 5 7.49e-07 3.30e-06
HDAC9 5 7.49e-07 3.30e-06
NFYA 5 7.49e-07 3.30e-06
NKX3-1 4 8.19e-07 3.56e-06
SMAD7 4 8.19e-07 3.56e-06
GATA3 6 1.02e-06 4.29e-06
MSC 4 1.28e-06 5.15e-06
NFATC2 4 1.28e-06 5.15e-06
FLI1 5 1.48e-06 5.82e-06
TWIST2 5 1.48e-06 5.82e-06
FOXO1 5 1.82e-06 6.92e-06
NR1I2 5 1.82e-06 6.92e-06
FOXP3 4 1.91e-06 7.21e-06
ERG 5 2.69e-06 9.52e-06
HDAC7 4 2.74e-06 9.66e-06
STAT2 4 2.74e-06 9.66e-06
TP73 4 2.74e-06 9.66e-06
MYCN 6 2.94e-06 1.03e-05
NFYC 4 3.81e-06 1.27e-05
ZEB1 4 3.81e-06 1.27e-05
YBX1 5 4.56e-06 1.47e-05
FHL2 3 5.07e-06 1.61e-05
FUS 3 5.07e-06 1.61e-05
NUPR1 3 5.07e-06 1.61e-05
PIAS2 3 5.07e-06 1.61e-05
SATB1 4 5.16e-06 1.63e-05
CTCF 5 7.33e-06 2.18e-05
CEBPD 4 8.89e-06 2.55e-05
DDIT3 4 8.89e-06 2.55e-05
ELF4 3 1.01e-05 2.84e-05
FOXQ1 3 1.01e-05 2.84e-05
IKBKB 3 1.01e-05 2.84e-05
LEF1 5 1.13e-05 3.10e-05
HMGA1 4 1.14e-05 3.11e-05
POU2F1 5 1.29e-05 3.44e-05
AATF 3 1.75e-05 4.43e-05
HSF2 3 1.75e-05 4.43e-05
NFKB2 3 1.75e-05 4.43e-05
TFAP4 3 1.75e-05 4.43e-05
ESR2 4 1.78e-05 4.48e-05
KLF6 4 1.78e-05 4.48e-05
ERCC2 3 2.79e-05 6.45e-05
IRF9 3 2.79e-05 6.45e-05
MAZ 3 2.79e-05 6.45e-05
PIAS1 3 2.79e-05 6.45e-05
SALL4 3 2.79e-05 6.45e-05
AHR 4 3.18e-05 7.18e-05
HDAC4 4 3.80e-05 8.34e-05
KLF8 3 4.16e-05 8.86e-05
NCOA3 3 4.16e-05 8.86e-05
NFATC1 3 4.16e-05 8.86e-05
SOX9 4 4.49e-05 9.42e-05
PROX1 3 5.90e-05 1.17e-04
SREBF1 4 6.15e-05 1.21e-04
MEN1 3 8.07e-05 1.53e-04
CREB5 3 1.07e-04 1.92e-04
GATA1 5 1.12e-04 2.00e-04
NF1 3 1.75e-04 2.88e-04
E2F3 3 2.17e-04 3.45e-04
FOSL2 3 2.17e-04 3.45e-04
JUNB 3 2.17e-04 3.45e-04
TCF3 3 2.17e-04 3.45e-04
TP63 3 2.17e-04 3.45e-04
RUNX1 4 3.25e-04 4.85e-04
FOXA2 3 3.83e-04 5.53e-04
HNF4A 4 5.08e-04 7.00e-04
NR1H4 3 5.29e-04 7.26e-04
PPARA 4 5.52e-04 7.51e-04
DEK 2 6.35e-04 8.42e-04
HDAC11 2 6.35e-04 8.42e-04
HOXA7 2 6.35e-04 8.42e-04
KDM4B 2 6.35e-04 8.42e-04
MED1 2 6.35e-04 8.42e-04
NR4A2 2 6.35e-04 8.42e-04
TAF1 2 6.35e-04 8.42e-04
TSC22D3 2 6.35e-04 8.42e-04
ZNF24 2 6.35e-04 8.42e-04
ARNT 3 7.06e-04 9.23e-04
FOXA1 3 7.06e-04 9.23e-04
ATF1 3 9.17e-04 1.15e-03
FOXL2 2 9.47e-04 1.18e-03
FOXO4 2 9.47e-04 1.18e-03
MAX 2 9.47e-04 1.18e-03
MYOD1 2 9.47e-04 1.18e-03
MYOG 2 9.47e-04 1.18e-03
MZF1 2 9.47e-04 1.18e-03
PAX3 2 9.47e-04 1.18e-03
RARG 2 9.47e-04 1.18e-03
RBL1 2 9.47e-04 1.18e-03
SMAD2 2 9.47e-04 1.18e-03
POU5F1 3 1.16e-03 1.41e-03
NFIC 3 1.30e-03 1.57e-03
ILF3 2 1.32e-03 1.58e-03
KLF10 2 1.32e-03 1.58e-03
HNF1A 3 1.45e-03 1.72e-03
ATF5 2 1.75e-03 2.04e-03
CEBPE 2 1.75e-03 2.04e-03
ING1 2 1.75e-03 2.04e-03
MYBL2 2 1.75e-03 2.04e-03
RBMX 2 1.75e-03 2.04e-03
ZBTB7A 2 1.75e-03 2.04e-03
CIITA 3 2.14e-03 2.45e-03
ELF3 2 2.24e-03 2.55e-03
SP4 2 2.24e-03 2.55e-03
ZNF148 2 2.24e-03 2.55e-03
CDX2 3 2.34e-03 2.66e-03
HSF1 3 2.34e-03 2.66e-03
REST 3 2.56e-03 2.87e-03
EGR2 2 2.78e-03 3.09e-03
EPAS1 2 2.78e-03 3.09e-03
EWSR1 2 2.78e-03 3.09e-03
LMO2 2 2.78e-03 3.09e-03
NFIL3 2 2.78e-03 3.09e-03
SNAI1 2 2.78e-03 3.09e-03
TFAP2C 2 2.78e-03 3.09e-03
ZNF382 2 2.78e-03 3.09e-03
HIC1 2 3.38e-03 3.69e-03
IRF4 2 3.38e-03 3.69e-03
KLF2 2 3.38e-03 3.69e-03
SPDEF 2 3.38e-03 3.69e-03
MYB 3 3.79e-03 4.11e-03
TCF7L2 2 4.04e-03 4.35e-03
IRF8 2 4.75e-03 5.06e-03
KAT2B 2 5.51e-03 5.83e-03
SP100 2 5.51e-03 5.83e-03
HOXA10 2 6.32e-03 6.65e-03
NR4A1 2 6.32e-03 6.65e-03
TBX21 2 6.32e-03 6.65e-03
RFX1 2 7.19e-03 7.50e-03
NFE2L2 2 8.10e-03 8.40e-03
RXRA 2 1.11e-02 1.14e-02
SREBF2 2 1.11e-02 1.14e-02
NR5A1 2 1.34e-02 1.37e-02
GATA4 2 1.58e-02 1.61e-02
SOX2 2 1.71e-02 1.74e-02
CREM 2 1.85e-02 1.87e-02
RARA 2 1.98e-02 2.01e-02
MITF 2 2.13e-02 2.15e-02

3. Diseases / Pathways associated with STAT3

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- Disease Ontology terms

#DescriptionTerm ID# of overlapped genesP valueFDR
1 cancer DOID:162 62 1.471e-45 7.970e-43
2 Malignant neoplasm of prostate DOID:10283 50 2.469e-42 1.031e-39
3 Malignant neoplasm of breast DOID:4241 54 5.693e-42 2.338e-39
4 disease DOID:4 90 1.705e-41 6.782e-39
5 Primary carcinoma of the liver cells DOID:684 41 1.430e-39 4.551e-37
6 Squamous cell carcinoma DOID:1749 36 1.206e-37 3.656e-35
7 Malignant neoplasm of stomach DOID:10534 37 2.767e-37 8.139e-35
8 Neoplasm Metastasis DOID:2619 41 3.189e-37 9.228e-35
9 Malignant Neoplasms DOID:462 54 1.700e-36 4.606e-34
10 Rheumatoid Arthritis DOID:7148 37 7.168e-35 1.772e-32
11 Endometriosis DOID:289 29 1.104e-33 2.488e-31
12 Melanoma DOID:1909 35 8.366e-33 1.790e-30
13 Renal Cell Carcinoma DOID:4450 29 7.864e-32 1.602e-29
14 Multiple Myeloma DOID:9538 26 2.915e-30 5.302e-28
15 Embryoma DOID:4766 42 3.350e-30 5.966e-28
16 Malignant neoplasm of ovary DOID:2144 29 5.993e-29 9.193e-27
17 Carcinoma of the Large Intestine DOID:1994 32 8.187e-28 1.115e-25
18 Infection DOID:945 30 1.123e-27 1.512e-25
19 Endometrial Carcinoma DOID:2871 23 1.389e-26 1.637e-24
20 Malignant tumor of colon DOID:219 27 8.611e-25 8.565e-23
21 Malignant neoplasm of cervix uteri DOID:4361 21 1.603e-24 1.540e-22
22 Lymphoma DOID:353 21 1.603e-24 1.540e-22
23 Atherosclerosis DOID:1936 22 6.312e-24 5.761e-22
24 Leukemia DOID:1240 27 6.793e-24 6.156e-22
25 Malignant neoplasm of pancreas DOID:1793 25 1.194e-23 1.060e-21
26 Degenerative polyarthritis DOID:455 19 5.631e-23 4.732e-21
27 Metastasis to Lymph Nodes DOID:10437 20 6.112e-23 5.103e-21
28 Carcinoma DOID:305 23 6.110e-23 5.103e-21
29 Adenocarcinoma DOID:299 23 1.883e-22 1.480e-20
30 Obesity DOID:9970 23 7.096e-22 5.299e-20
31 Stomach Carcinoma DOID:5517 19 1.791e-21 1.300e-19
32 Glioma DOID:2627 23 2.188e-21 1.565e-19
33 Multiple Sclerosis DOID:2377 20 2.540e-21 1.807e-19
34 Diabetes Mellitus, Non-Insulin-Dependent DOID:9352 27 3.261e-21 2.275e-19
35 Malignant neoplasm of lung DOID:1324 25 5.980e-21 4.061e-19
36 Dental Plaque DOID:13598 16 6.415e-21 4.344e-19
37 Cervical Squamous Cell Carcinoma DOID:3744 17 2.415e-20 1.518e-18
38 Malignant Glioma DOID:3070 21 3.610e-20 2.220e-18
39 Hodgkin's disease, unspecified type DOID:8567 16 3.115e-19 1.740e-17
40 Malignant neoplasm of endometrium DOID:5654 15 7.291e-19 3.942e-17
41 Systemic infection DOID:2288 15 1.203e-17 5.570e-16
42 Uterine Fibroids DOID:13223 12 2.094e-17 9.340e-16
43 Astrocytoma DOID:3069 14 2.515e-17 1.117e-15
44 Primary Tumor DOID:8176 15 3.341e-17 1.467e-15
45 Carcinoma of lung DOID:3905 12 6.420e-17 2.707e-15
46 Asthma DOID:2841 18 6.511e-17 2.729e-15
47 Glioblastoma DOID:3068 16 7.496e-17 3.104e-15
48 Carcinoma of Nasopharynx DOID:9261 13 1.146e-16 4.633e-15
49 Malignant neoplasm of urinary bladder DOID:11054 15 5.736e-16 2.098e-14
50 Coronary Arteriosclerosis DOID:3363 17 5.807e-16 2.115e-14
51 Osteosarcoma DOID:3347 14 9.103e-16 3.202e-14
52 Myeloid leukemia, acute DOID:9119 18 1.561e-15 5.387e-14
53 Breast Carcinoma DOID:3459 16 1.701e-15 5.822e-14
54 Pre-Eclampsia DOID:10591 15 4.013e-15 1.302e-13
55 Myeloid leukemia, chronic DOID:8552 11 1.747e-14 5.189e-13
56 Infiltrating Malignant Neoplasm DOID:8062 11 2.297e-14 6.686e-13
57 Hypertension induced by pregnancy DOID:12684 15 2.491e-14 7.207e-13
58 Esophageal carcinoma DOID:1107 9 2.621e-14 7.507e-13
59 Small cell carcinoma of lung DOID:5409 13 3.860e-14 1.073e-12
60 Congenital Abnormality DOID:759 18 3.923e-14 1.088e-12
61 Adenocarcinoma of Esophagus DOID:4914 10 4.530e-14 1.244e-12
62 Malignant neoplasm of esophagus DOID:1104 13 4.548e-14 1.248e-12
63 Leukemia, Lymphocytic, chronic DOID:1040 14 4.723e-14 1.295e-12
64 Polycystic Ovary syndrome DOID:11612 12 5.601e-14 1.514e-12
65 Prostate carcinoma DOID:10286 12 5.601e-14 1.514e-12
66 Rheumatism DOID:4256 10 6.301e-14 1.693e-12
67 Carcinoma, Transitional Cell DOID:3995 11 6.428e-14 1.718e-12
68 acute leukemia DOID:12603 11 8.189e-14 2.132e-12
69 Malignant neoplasm of mouth, unspecified DOID:8894 11 8.189e-14 2.132e-12
70 Liver neoplasms DOID:3571 12 9.935e-14 2.552e-12
71 Systemic Scleroderma DOID:418 13 1.163e-13 2.948e-12
72 Epithelial ovarian cancer DOID:4001 10 2.127e-13 5.139e-12
73 Osteosarcoma of Bone DOID:3376 12 2.430e-13 5.837e-12
74 Neuroblastoma DOID:769 14 2.473e-13 5.918e-12
75 Hypertension DOID:10763 15 2.600e-13 6.148e-12
76 Colonic Neoplasms DOID:235 9 3.503e-13 8.022e-12
77 Adenovirus Infections DOID:3124 11 3.868e-13 8.787e-12
78 chronic Obstructive Airway disease DOID:3083 12 5.559e-13 1.230e-11
79 Ankylosing spondylitis DOID:7147 8 5.697e-13 1.257e-11
80 Cholangiocarcinoma DOID:4947 10 6.254e-13 1.362e-11
81 Arthritis DOID:848 10 6.254e-13 1.362e-11
82 Systemic lupus erythematosus DOID:9074 14 6.931e-13 1.496e-11
83 Neoplasm, Ovarian DOID:2394 11 1.243e-12 2.539e-11
84 HIV Infections DOID:526 13 1.336e-12 2.709e-11
85 Cerebrovascular accident DOID:3455 12 1.610e-12 3.211e-11
86 Adenoma DOID:657 12 1.860e-12 3.665e-11
87 Esophageal Neoplasms DOID:5041 12 2.466e-12 4.756e-11
88 Tuberculosis DOID:399 11 2.528e-12 4.861e-11
89 Celiac disease DOID:10608 9 2.561e-12 4.918e-11
90 Ulcerative colitis, unspecified DOID:8577 12 4.247e-12 7.854e-11
91 Alzheimer's disease DOID:10652 16 5.411e-12 9.745e-11
92 Fibroid Tumor DOID:127 9 5.959e-12 1.066e-10
93 Lymphatic Metastasis DOID:4100 7 6.934e-12 1.226e-10
94 Hamman-Rich syndrome DOID:2797 9 1.002e-11 1.702e-10
95 Ischemia DOID:326 10 1.069e-11 1.807e-10
96 Bacterial Infections DOID:104 7 1.225e-11 2.035e-10
97 Cervix carcinoma DOID:2893 9 1.285e-11 2.125e-10
98 Neoplasms, Epithelial DOID:157 8 1.591e-11 2.580e-10
99 Thyroid carcinoma DOID:3963 9 1.636e-11 2.644e-10
100 Periodontitis DOID:824 9 2.069e-11 3.279e-10
101 Regional enteritis of unspecified site DOID:8778 11 2.181e-11 3.439e-10
102 Colon Carcinoma DOID:1520 10 5.944e-11 8.509e-10
103 Proliferative diabetic retinopathy DOID:13207 6 7.067e-11 9.948e-10
104 Germ cell tumor DOID:2994 7 8.096e-11 1.124e-09
105 Unspecified myeloid leukemia DOID:8692 9 9.120e-11 1.253e-09
106 Anemia DOID:2355 7 1.207e-10 1.611e-09
107 Meningioma DOID:3565 9 1.333e-10 1.764e-09
108 Malignant Squamous Cell Neoplasm DOID:5512 6 1.405e-10 1.848e-09
109 Diabetes Mellitus DOID:9351 11 2.517e-10 3.140e-09
110 Temporal Arteritis DOID:13375 6 2.593e-10 3.216e-09
111 Stomach Neoplasms DOID:4713 8 2.597e-10 3.220e-09
112 malaria DOID:12365 8 3.269e-10 3.953e-09
113 Aortic Aneurysm, Abdominal DOID:7693 7 3.525e-10 4.230e-09
114 Nodular lymphoma DOID:8524 7 6.617e-10 7.472e-09
115 Prostatic Hypertrophy, Benign DOID:11131 8 1.141e-09 1.225e-08
116 Hepatitis C, chronic DOID:2049 8 1.141e-09 1.225e-08
117 Testicular dysfunction DOID:11019 8 1.141e-09 1.225e-08
118 Advanced Cancer DOID:2337 8 1.141e-09 1.225e-08
119 Breast Cancer Stage IV DOID:6267 8 1.141e-09 1.225e-08
120 Carcinoma in situ DOID:8719 6 1.188e-09 1.267e-08
121 Lichen planus DOID:9201 5 1.200e-09 1.279e-08
122 autoimmune disease DOID:417 9 1.282e-09 1.356e-08
123 Pituitary Adenoma DOID:3829 7 1.541e-09 1.596e-08
124 Diabetic Retinopathy DOID:8947 8 1.659e-09 1.704e-08
125 Behcet syndrome DOID:13241 8 1.986e-09 2.004e-08
126 HTLV-I Infections DOID:323 5 2.684e-09 2.621e-08
127 Subacute sclerosing panencephalitis DOID:8970 5 2.684e-09 2.621e-08
128 schizophrenia DOID:5419 13 3.825e-09 3.590e-08
129 Adenocarcinoma of the Pancreas DOID:4074 8 3.922e-09 3.678e-08
130 Helicobacter Infections DOID:3686 6 3.951e-09 3.698e-08
131 Colorectal Neoplasms DOID:1985 7 5.147e-09 4.691e-08
132 Lung Metastases DOID:2158 6 5.609e-09 5.056e-08
133 Prostatic Neoplasms DOID:514 9 7.553e-09 6.609e-08
134 Mucocutaneous Lymph Node syndrome DOID:13378 6 7.804e-09 6.815e-08
135 Severe acute Respiratory syndrome DOID:2945 6 7.804e-09 6.815e-08
136 Bronchopulmonary Dysplasia DOID:11651 5 9.724e-09 8.248e-08
137 Dermatomyositis DOID:10223 5 9.724e-09 8.248e-08
138 Essential Hypertension DOID:10825 8 1.130e-08 9.412e-08
139 Hepatitis B, chronic DOID:2042 6 1.434e-08 1.166e-07
140 Neuroendocrine Tumors DOID:169 6 1.434e-08 1.166e-07
141 Coronary heart disease DOID:3393 8 1.489e-08 1.205e-07
142 Laryngeal Squamous Cell Carcinoma DOID:2876 6 1.900e-08 1.483e-07
143 Pulmonary Emphysema DOID:9675 6 1.900e-08 1.483e-07
144 Endometrial adenocarcinoma DOID:2870 6 1.900e-08 1.483e-07
145 Lupus Vulgaris DOID:5380 6 3.211e-08 2.366e-07
146 End stage renal failure DOID:783 7 3.444e-08 2.517e-07
147 Diabetic Nephropathy DOID:2370 8 3.632e-08 2.626e-07
148 Age related macular degeneration DOID:10871 6 4.103e-08 2.917e-07
149 Pulmonary Fibrosis DOID:3770 6 4.103e-08 2.917e-07
150 Fetal Growth Retardation DOID:13294 6 4.103e-08 2.917e-07
151 Liver Metastases DOID:12722 7 4.751e-08 3.303e-07
152 Squamous Cell Carcinoma of Esophagus DOID:3748 9 5.596e-08 3.819e-07
153 Endometriosis of uterus DOID:288 5 6.170e-08 4.172e-07
154 Ewings sarcoma DOID:3369 6 6.503e-08 4.373e-07
155 Adenocarcinoma of Lung DOID:3910 8 7.207e-08 4.788e-07
156 Lupus erythematosus DOID:8857 6 8.079e-08 5.282e-07
157 Graves' disease DOID:12361 7 8.648e-08 5.605e-07
158 Polymyositis DOID:10222 5 8.920e-08 5.760e-07
159 cardiovascular system disease DOID:1287 5 8.920e-08 5.760e-07
160 Leukemia, T-Cell DOID:715 5 8.920e-08 5.760e-07
161 Lung Neoplasms DOID:3683 7 9.961e-08 6.332e-07
162 Infertility DOID:5223 7 9.961e-08 6.332e-07
163 acute myocardial infarction DOID:9408 4 1.031e-07 6.515e-07
164 Down syndrome DOID:14250 8 1.100e-07 6.913e-07
165 syndrome DOID:225 12 1.306e-07 8.026e-07
166 Metastatic Melanoma DOID:4358 6 1.479e-07 8.920e-07
167 Kidney diseases DOID:557 7 1.703e-07 1.014e-06
168 Uremia DOID:4676 5 1.729e-07 1.026e-06
169 Retinoblastoma DOID:768 6 1.785e-07 1.055e-06
170 IGA Glomerulonephritis DOID:2986 6 1.785e-07 1.055e-06
171 Biliary Atresia DOID:13608 4 2.051e-07 1.187e-06
172 disease of metabolism DOID:0014667 5 2.332e-07 1.334e-06
173 Periodontal diseases DOID:3388 5 2.332e-07 1.334e-06
174 Sarcoidosis DOID:11335 6 3.030e-07 1.672e-06
175 Proteinuria DOID:576 5 3.091e-07 1.698e-06
176 malaria, cerebral DOID:14069 4 3.669e-07 1.966e-06
177 Gingivitis DOID:3087 4 3.669e-07 1.966e-06
178 Cutaneous Fibrous Histiocytoma DOID:4418 4 3.669e-07 1.966e-06
179 Epstein-Barr Virus Infections DOID:2938 5 4.032e-07 2.127e-06
180 Pancreatitis, relapsing DOID:13315 5 4.032e-07 2.127e-06
181 Transient hypertension of pregnancy DOID:1257 4 6.080e-07 3.022e-06
182 Influenza DOID:8469 5 8.271e-07 3.940e-06
183 Dependence DOID:9973 7 8.297e-07 3.951e-06
184 brucellosis DOID:11077 4 9.499e-07 4.428e-06
185 Malnutrition DOID:8452 4 9.499e-07 4.428e-06
186 Pleural Effusion, Malignant DOID:13906 4 9.499e-07 4.428e-06
187 Leukemia, Lymphocytic, acute DOID:9952 6 1.010e-06 4.666e-06
188 Cystic Fibrosis DOID:1485 6 1.155e-06 5.236e-06
189 Carcinoma of larynx DOID:2600 4 1.417e-06 6.261e-06
190 esotropia DOID:9840 4 1.417e-06 6.261e-06
191 Kaposi Sarcoma DOID:8632 5 1.867e-06 7.944e-06
192 Intraocular Melanoma DOID:6039 5 1.867e-06 7.944e-06
193 Cancer of Skin DOID:4159 4 2.034e-06 8.530e-06
194 Diabetes, Gestational DOID:11714 5 2.242e-06 9.264e-06
195 Gastrointestinal Stromal Tumors DOID:9253 5 2.242e-06 9.264e-06
196 Spontaneous abortion DOID:722 6 2.419e-06 9.883e-06
197 Familial Mediterranean Fever DOID:2987 4 2.831e-06 1.132e-05
198 Cancer of Rectum DOID:1993 4 2.831e-06 1.132e-05
199 Primary biliary cirrhosis DOID:12236 5 3.170e-06 1.246e-05
200 Papillary thyroid carcinoma DOID:3969 5 3.734e-06 1.427e-05
201 Polyp of corpus uteri DOID:9042 3 4.048e-06 1.529e-05
202 Phyllodes Tumor DOID:2608 3 4.048e-06 1.529e-05
203 Heart diseases DOID:114 3 4.048e-06 1.529e-05
204 chronic leukemia NOS DOID:1036 3 4.048e-06 1.529e-05
205 Mucoepidermoid Carcinoma DOID:4531 3 4.048e-06 1.529e-05
206 Glomerulonephritis DOID:2921 4 5.088e-06 1.846e-05
207 Bladder Neoplasm DOID:5428 5 5.098e-06 1.848e-05
208 Diabetes Mellitus, Insulin-Dependent DOID:9744 5 5.912e-06 2.101e-05
209 Parkinson disease DOID:14330 7 6.273e-06 2.215e-05
210 Chondrosarcoma DOID:3371 4 6.615e-06 2.311e-05
211 Hemolytic-Uremic syndrome DOID:12554 4 6.615e-06 2.311e-05
212 Malignant Pleural Mesothelioma DOID:7474 4 6.615e-06 2.311e-05
213 Burkitt's tumor or lymphoma DOID:8584 4 6.615e-06 2.311e-05
214 Basal cell carcinoma DOID:2513 5 6.824e-06 2.370e-05
215 Malignant neoplasm of liver DOID:12300 5 7.843e-06 2.664e-05
216 Tropical Spastic Paraparesis DOID:321 3 8.051e-06 2.726e-05
217 Mycobacterium Infections, Atypical DOID:412 3 8.051e-06 2.726e-05
218 disease of capillaries DOID:1271 3 8.051e-06 2.726e-05
219 Kidney Failure, chronic DOID:784 4 8.456e-06 2.847e-05
220 Gallbladder Carcinoma DOID:4948 4 8.456e-06 2.847e-05
221 Brain Neoplasms DOID:1319 5 8.978e-06 2.999e-05
222 Osteoporosis DOID:11476 5 1.163e-05 3.718e-05
223 malaria, falciparum DOID:14067 3 1.401e-05 4.333e-05
224 Lymphopenia DOID:614 3 1.401e-05 4.333e-05
225 Adrenocortical carcinoma DOID:3948 3 1.401e-05 4.333e-05
226 Primary CNS Lymphoma DOID:3233 3 1.401e-05 4.333e-05
227 Malignant neoplasm of thyroid DOID:10008 5 1.485e-05 4.547e-05
228 Huntington disease DOID:12858 4 1.625e-05 4.905e-05
229 Neurodegenerative disorders DOID:4874 5 1.671e-05 5.022e-05
230 Heart failure DOID:6000 6 1.778e-05 5.288e-05
231 Neuromuscular diseases DOID:440 3 2.230e-05 6.401e-05
232 Bronchial Hyperreactivity DOID:5783 3 2.230e-05 6.401e-05
233 Schistosoma mansonii infection DOID:3468 3 2.230e-05 6.401e-05
234 Bronchiolitis Obliterans DOID:2799 3 2.230e-05 6.401e-05
235 Breast diseases DOID:3463 3 2.230e-05 6.401e-05
236 acute pancreatitis DOID:2913 4 2.377e-05 6.753e-05
237 Sarcoma DOID:1115 4 2.377e-05 6.753e-05
238 Rhabdomyosarcoma DOID:3247 4 2.836e-05 7.796e-05
239 Cholelithiasis DOID:10211 4 2.836e-05 7.796e-05
240 Medullary carcinoma of thyroid DOID:3973 4 2.836e-05 7.796e-05
241 anorexia nervosa DOID:8689 4 2.836e-05 7.796e-05
242 Myelofibrosis DOID:4971 4 2.836e-05 7.796e-05
243 acoustic neuroma DOID:12689 3 3.326e-05 8.906e-05
244 Lyme disease DOID:11729 3 3.326e-05 8.906e-05
245 Fibroadenoma DOID:2693 3 3.326e-05 8.906e-05
246 Vasculitis DOID:865 3 3.326e-05 8.906e-05
247 Takayasu's Arteritis DOID:13377 3 3.326e-05 8.906e-05
248 Ptosis DOID:9308 3 3.326e-05 8.906e-05
249 Hyperlipidemia DOID:1168 4 3.356e-05 8.971e-05
250 Malignant mesothelioma DOID:1790 4 3.356e-05 8.971e-05
251 Hyperinsulinism DOID:2018 4 4.602e-05 1.159e-04
252 Thrombocytosis DOID:2228 3 4.725e-05 1.184e-04
253 Ductal Carcinoma DOID:3007 5 6.132e-05 1.462e-04
254 Hypercholesterolemia DOID:2487 4 6.157e-05 1.467e-04
255 Intracranial Aneurysm DOID:10941 3 6.462e-05 1.526e-04
256 Atrophic gastritis DOID:8929 3 6.462e-05 1.526e-04
257 Arteriosclerosis DOID:2349 3 6.462e-05 1.526e-04
258 pancreatitis, alcoholic DOID:4988 3 6.462e-05 1.526e-04
259 Barrett's esophagus DOID:9206 4 7.063e-05 1.636e-04
260 Neck Neoplasms DOID:4725 3 8.568e-05 1.917e-04
261 Osteoarthritis, Knee DOID:14282 3 8.568e-05 1.917e-04
262 Alopecia Areata DOID:986 3 8.568e-05 1.917e-04
263 Choriocarcinoma DOID:3594 3 8.568e-05 1.917e-04
264 Rheumatic Heart disease DOID:9814 3 8.568e-05 1.917e-04
265 Bone diseases DOID:1290 3 8.568e-05 1.917e-04
266 Intraepithelial Neoplasia DOID:5616 3 8.568e-05 1.917e-04
267 Fatty Liver DOID:9452 3 8.568e-05 1.917e-04
268 Disseminated Malignant Neoplasm DOID:2332 4 9.160e-05 2.024e-04
269 Acquired Immunodeficiency syndrome DOID:635 4 9.160e-05 2.024e-04
270 Lipodystrophy DOID:811 3 1.108e-04 2.355e-04
271 thyroid gland disease DOID:50 3 1.108e-04 2.355e-04
272 Gouts DOID:13189 3 1.108e-04 2.355e-04
273 Neurilemmoma DOID:3192 3 1.108e-04 2.355e-04
274 Yersinia infections DOID:3300 5 1.256e-04 2.611e-04
275 Liver Cirrhosis DOID:5082 4 1.311e-04 2.707e-04
276 Purpura, Thrombocytopenic, Idiopathic DOID:2220 3 1.402e-04 2.863e-04
277 Hereditary Nonpolyposis Colorectal Neoplasms DOID:3040 3 1.402e-04 2.863e-04
278 Duodenal Ulcer DOID:1724 3 1.402e-04 2.863e-04
279 Oligodendroglioma DOID:3181 3 1.402e-04 2.863e-04
280 Gastritis DOID:4029 3 1.402e-04 2.863e-04
281 Thrombocytopenia DOID:1588 3 1.743e-04 3.415e-04
282 Labor, Premature DOID:10875 3 1.743e-04 3.415e-04
283 Myasthenia Gravis DOID:437 3 1.743e-04 3.415e-04
284 Thrombophilia DOID:2452 3 2.134e-04 4.019e-04
285 Hypothyroidism DOID:11630 3 2.134e-04 4.019e-04
286 chronic rejection of renal transplant DOID:2985 3 2.134e-04 4.019e-04
287 Virus diseases DOID:934 5 2.321e-04 4.306e-04
288 Premature Birth DOID:10874 3 2.577e-04 4.688e-04
289 Obesity, Morbid DOID:11981 3 2.577e-04 4.688e-04
290 chronic sinusitis NOS DOID:9564 3 3.075e-04 5.402e-04
291 Sezary's disease DOID:8541 3 3.075e-04 5.402e-04
292 Tuberculosis, Pulmonary DOID:2957 3 3.075e-04 5.402e-04
293 Medulloblastoma DOID:3858 4 3.520e-04 6.036e-04
294 Dermatitis, Atopic DOID:3310 5 4.191e-04 6.958e-04
295 Lymphoproliferative disorders DOID:619 3 4.249e-04 7.045e-04
296 Sudden infant death syndrome DOID:9007 3 4.249e-04 7.045e-04
297 chronic simple glaucoma DOID:1070 3 4.249e-04 7.045e-04
298 Adenocarcinoma, Clear Cell DOID:4468 3 4.930e-04 7.959e-04
299 Hepatitis DOID:2237 3 4.930e-04 7.959e-04
300 Pancreatitis DOID:4989 3 4.930e-04 7.959e-04
301 Osteoporosis, Postmenopausal DOID:12561 2 5.467e-04 8.650e-04
302 Aortic Aneurysm, Thoracic DOID:14004 2 5.467e-04 8.650e-04
303 Burning Mouth syndrome DOID:4331 2 5.467e-04 8.650e-04
304 Klinefelter's syndrome DOID:1921 2 5.467e-04 8.650e-04
305 Pemphigus DOID:9182 2 5.467e-04 8.650e-04
306 Leishmaniasis, Visceral DOID:9146 2 5.467e-04 8.650e-04
307 Urticaria Pigmentosa DOID:12309 2 5.467e-04 8.650e-04
308 Mastocytosis DOID:350 2 5.467e-04 8.650e-04
309 Brain Infarction DOID:3454 2 5.467e-04 8.650e-04
310 Metastatic Adenocarcinoma DOID:3027 2 5.467e-04 8.650e-04
311 viral hepatitis DOID:1884 2 5.467e-04 8.650e-04
312 Localized Malignant Neoplasm DOID:11933 2 5.467e-04 8.650e-04
313 Pituitary Neoplasms DOID:1785 3 5.678e-04 8.939e-04
314 Kidney Failure DOID:1074 3 5.678e-04 8.939e-04
315 Ataxia Telangiectasia DOID:12704 3 6.494e-04 9.973e-04
316 Dermatitis DOID:2723 3 6.494e-04 9.973e-04
317 Amyotrophic Lateral Sclerosis DOID:332 4 7.092e-04 1.072e-03
318 Bone Metastases DOID:2759 3 7.381e-04 1.104e-03
319 Azoospermia DOID:14227 3 7.381e-04 1.104e-03
320 Thromboangiitis Obliterans DOID:12918 2 8.161e-04 1.202e-03
321 Adenoma of Parathyroid DOID:7608 2 8.161e-04 1.202e-03
322 Refractory Cancer DOID:5666 2 8.161e-04 1.202e-03
323 Malignant neoplasm of tongue, unspecified DOID:8649 2 8.161e-04 1.202e-03
324 Malignant neoplasm of male breast DOID:9796 2 8.161e-04 1.202e-03
325 Mycobacterium Infections DOID:2757 2 8.161e-04 1.202e-03
326 Chordoma DOID:3302 2 8.161e-04 1.202e-03
327 Adenocarcinoma of Rectum DOID:1996 2 8.161e-04 1.202e-03
328 Sicca syndrome DOID:416 3 9.378e-04 1.349e-03
329 Herpangina DOID:10883 3 9.378e-04 1.349e-03
330 Solid Tumor DOID:5650 3 1.049e-03 1.481e-03
331 Neoplasm, Thyroid DOID:1781 3 1.049e-03 1.481e-03
332 Carcinoma, Papillary DOID:3113 3 1.049e-03 1.481e-03
333 Sarcoma, Clear Cell DOID:4233 2 1.137e-03 1.581e-03
334 Recurrent Cancer of Prostate DOID:8045 2 1.137e-03 1.581e-03
335 Uterine Cancer DOID:4363 2 1.137e-03 1.581e-03
336 nervous system disease DOID:863 2 1.137e-03 1.581e-03
337 Angiomyolipoma DOID:3314 2 1.137e-03 1.581e-03
338 Eosinophilia DOID:999 2 1.137e-03 1.581e-03
339 Myoma DOID:2691 2 1.137e-03 1.581e-03
340 Extramammary Paget's disease DOID:2099 2 1.137e-03 1.581e-03
341 Glaucoma DOID:1686 3 1.169e-03 1.618e-03
342 pneumonia DOID:552 3 1.169e-03 1.618e-03
343 Migraine DOID:6364 3 1.297e-03 1.764e-03
344 Vascular diseases DOID:178 3 1.297e-03 1.764e-03
345 Coronary Stenosis DOID:4248 2 1.508e-03 2.004e-03
346 Squamous cell carcinoma of skin DOID:3151 2 1.508e-03 2.004e-03
347 Metabolic syndrome X DOID:14221 2 1.508e-03 2.004e-03
348 Bronchiolitis DOID:2942 2 1.508e-03 2.004e-03
349 CNS metastases DOID:928 2 1.508e-03 2.004e-03
350 Fibrosarcoma DOID:3355 2 1.508e-03 2.004e-03
351 Abortion, Habitual DOID:11946 2 1.508e-03 2.004e-03
352 polyphagia DOID:8669 3 1.578e-03 2.082e-03
353 autistic disorder DOID:12849 4 1.685e-03 2.202e-03
354 Neoplasm, Pancreatic DOID:3588 3 1.731e-03 2.254e-03
355 Liver diseases DOID:409 3 1.894e-03 2.434e-03
356 Leiomyosarcoma DOID:1967 2 1.930e-03 2.474e-03
357 Cervical Adenocarcinoma DOID:3702 2 1.930e-03 2.474e-03
358 Metaplastic Polyp DOID:6443 2 1.930e-03 2.474e-03
359 Intermediate coronary syndrome DOID:8805 2 1.930e-03 2.474e-03
360 Polycythemia DOID:8432 2 1.930e-03 2.474e-03
361 Stage I NSCLC DOID:4820 2 1.930e-03 2.474e-03
362 Respiratory Syncytial Virus Infections DOID:1273 2 1.930e-03 2.474e-03
363 Respiratory Distress syndrome, Newborn DOID:11395 2 1.930e-03 2.474e-03
364 Retinal diseases DOID:5679 3 2.248e-03 2.820e-03
365 Pseudoxanthoma Elasticum DOID:2738 2 2.401e-03 2.976e-03
366 Cushing syndrome DOID:12252 2 2.401e-03 2.976e-03
367 Muscular Dystrophy, Duchenne DOID:11723 2 2.401e-03 2.976e-03
368 Henoch-Schoenlein Purpura DOID:11123 2 2.401e-03 2.976e-03
369 Uveitis DOID:13141 2 2.401e-03 2.976e-03
370 hepatitis B DOID:2043 2 2.401e-03 2.976e-03
371 Thalassemia DOID:10241 2 2.401e-03 2.976e-03
372 Leukoencephalopathy, Progressive Multifocal DOID:643 3 2.439e-03 3.017e-03
373 dementia DOID:1307 3 2.639e-03 3.231e-03
374 Hyperglycemia DOID:4195 3 2.850e-03 3.456e-03
375 Pancreatic carcinoma DOID:4905 3 2.850e-03 3.456e-03
376 Severe Combined Immunodeficiency DOID:627 2 2.920e-03 3.530e-03
377 Thrombophlebitis DOID:3875 2 2.920e-03 3.530e-03
378 Metastatic malignant neoplasm to brain DOID:927 2 2.920e-03 3.530e-03
379 Atrophic condition of skin DOID:2733 2 2.920e-03 3.530e-03
380 Thrombocythemia, Hemorrhagic DOID:2224 2 2.920e-03 3.530e-03
381 Rabies DOID:11260 4 3.194e-03 3.819e-03
382 Respiratory Distress syndrome, Adult DOID:11394 2 3.486e-03 4.117e-03
383 Ependymoma DOID:4844 2 4.100e-03 4.765e-03
384 Encephalitis DOID:9588 2 4.100e-03 4.765e-03
385 Leprosy DOID:1024 2 4.100e-03 4.765e-03
386 Myeloproliferative disease DOID:2356 2 4.100e-03 4.765e-03
387 Infection of amniotic sac and membranes DOID:13429 2 4.760e-03 5.435e-03
388 Hyperandrogenism DOID:11613 2 4.760e-03 5.435e-03
389 Sarcoma, Synovial DOID:5485 2 4.760e-03 5.435e-03
390 Alopecia DOID:987 2 4.760e-03 5.435e-03
391 tuberous sclerosis DOID:13515 2 5.466e-03 6.160e-03
392 Seminoma DOID:4440 2 5.466e-03 6.160e-03
393 Adenoid Cystic Carcinoma DOID:4866 2 5.466e-03 6.160e-03
394 Kidney Neoplasms DOID:263 2 6.216e-03 6.923e-03
395 Carcinoma, Endometrioid DOID:3000 2 7.010e-03 7.718e-03
396 Skin Melanoma DOID:8923 2 7.010e-03 7.718e-03
397 Mesothelioma DOID:2645 2 7.848e-03 8.563e-03
398 Malignant neoplasm of gallbladder DOID:8090 2 7.848e-03 8.563e-03
399 mental depression DOID:1596 3 8.493e-03 9.201e-03
400 Spinal Dysraphism DOID:1089 2 8.729e-03 9.439e-03
401 Cystadenocarcinoma, Serous DOID:3114 2 9.651e-03 1.037e-02
402 Malignant neoplasm of kidney DOID:3676 2 9.651e-03 1.037e-02
403 Cerebral Infarction DOID:3526 2 1.062e-02 1.133e-02
404 Myocardial Ischemia DOID:3394 2 1.062e-02 1.133e-02
405 Vitiligo DOID:12306 2 1.062e-02 1.133e-02
406 Carcinoma of bladder DOID:4007 2 1.162e-02 1.234e-02
407 neuropathy DOID:870 2 1.375e-02 1.447e-02
408 attention deficit hyperactivity disorder DOID:1094 2 1.603e-02 1.673e-02
409 Lung diseases DOID:850 2 1.603e-02 1.673e-02
410 Sickle Cell Anemia DOID:10923 2 1.723e-02 1.792e-02
411 Amyloidosis DOID:9120 2 1.723e-02 1.792e-02
412 Adenocarcinoma of the Colon DOID:234 2 1.847e-02 1.915e-02
413 Adenocarcinoma of Prostate DOID:2526 2 1.847e-02 1.915e-02
414 Hypertension, Pulmonary DOID:6432 2 1.974e-02 2.041e-02
415 Heart Failure, Congestive DOID:395 2 2.239e-02 2.304e-02
416 Asthma, allergic NOS DOID:9415 2 2.961e-02 3.020e-02
417 alcoholic intoxication, chronic DOID:1598 2 3.596e-02 3.648e-02

- KEGG pathway/disease terms

#DescriptionTerm ID# of overlapped genesP valueFDR
1 Jak-STAT signaling pathway hsa04630 30 8.017e-34 1.830e-31
2 Pathways in cancer hsa05200 35 1.446e-27 1.787e-25
3 Measles hsa05162 22 1.809e-23 1.583e-21
4 PI3K-Akt signaling pathway hsa04151 29 2.814e-22 2.291e-20
5 Hepatitis B hsa05161 20 8.628e-20 5.884e-18
6 Cytokine-cytokine receptor interaction hsa04060 22 6.085e-17 3.117e-15
7 Bladder cancer hsa05219 12 1.781e-16 8.533e-15
8 Proteoglycans in cancer hsa05205 18 1.569e-14 5.991e-13
9 FoxO signaling pathway hsa04068 15 8.955e-14 2.970e-12
10 TNF signaling pathway hsa04668 14 1.042e-13 3.387e-12
11 Influenza A hsa05164 16 3.063e-13 9.113e-12
12 HTLV-I infection hsa05166 18 9.637e-13 2.642e-11
13 Rheumatoid arthritis hsa05323 12 3.247e-12 8.001e-11
14 Melanoma hsa05218 11 5.758e-12 1.347e-10
15 Transcriptional misregulation in cancer hsa05202 15 6.195e-12 1.436e-10
16 Prolactin signaling pathway hsa04917 11 6.737e-12 1.552e-10
17 Herpes simplex infection hsa05168 15 9.203e-12 2.061e-10
18 MicroRNAs in cancer hsa05206 18 1.020e-11 2.265e-10
19 HIF-1 signaling pathway hsa04066 12 1.874e-11 3.977e-10
20 Chagas disease (American trypanosomiasis) hsa05142 12 2.103e-11 4.443e-10
21 Hepatitis C hsa05160 13 2.456e-11 5.107e-10
22 Malaria hsa05144 9 1.105e-10 2.015e-09
23 Small cell lung cancer hsa05222 10 9.862e-10 1.429e-08
24 Toxoplasmosis hsa05145 11 1.488e-09 2.070e-08
25 Pancreatic cancer hsa05212 9 1.693e-09 2.318e-08
26 p53 signaling pathway hsa04115 9 2.216e-09 2.931e-08
27 Leishmaniasis hsa05140 9 3.701e-09 4.655e-08
28 Epstein-Barr virus infection hsa05169 13 3.825e-09 4.798e-08
29 Chronic myeloid leukemia hsa05220 9 4.187e-09 5.179e-08
30 Osteoclast differentiation hsa04380 11 4.498e-09 5.492e-08
31 Colorectal cancer hsa05210 8 2.211e-08 2.297e-07
32 Prostate cancer hsa05215 9 2.417e-08 2.477e-07
33 Endometrial cancer hsa05213 7 1.310e-07 1.087e-06
34 African trypanosomiasis hsa05143 6 2.142e-07 1.680e-06
35 Non-alcoholic fatty liver disease (NAFLD) hsa04932 10 2.185e-07 1.705e-06
36 Apoptosis hsa04210 8 2.621e-07 2.011e-06
37 Cell cycle hsa04110 9 4.192e-07 3.028e-06
38 Focal adhesion hsa04510 11 4.831e-07 3.414e-06
39 MAPK signaling pathway hsa04010 12 5.232e-07 3.666e-06
40 Glioma hsa05214 7 6.102e-07 4.180e-06
41 Inflammatory bowel disease (IBD) hsa05321 7 6.102e-07 4.180e-06
42 Central carbon metabolism in cancer hsa05230 7 7.502e-07 4.993e-06
43 Tuberculosis hsa05152 10 9.398e-07 6.044e-06
44 Toll-like receptor signaling pathway hsa04620 8 1.411e-06 8.525e-06
45 Hippo signaling pathway hsa04390 9 2.547e-06 1.403e-05
46 Rap1 signaling pathway hsa04015 10 4.535e-06 2.273e-05
47 NF-kappa B signaling pathway hsa04064 7 5.837e-06 2.811e-05
48 Estrogen signaling pathway hsa04915 7 1.015e-05 4.547e-05
49 Renal cell carcinoma hsa05211 6 1.081e-05 4.804e-05
50 Complement and coagulation cascades hsa04610 6 1.395e-05 5.962e-05
51 T cell receptor signaling pathway hsa04660 7 1.399e-05 5.964e-05
52 Adipocytokine signaling pathway hsa04920 6 1.514e-05 6.385e-05
53 Pertussis hsa05133 6 2.242e-05 8.891e-05
54 Viral carcinogenesis hsa05203 9 2.533e-05 9.841e-05
55 Ras signaling pathway hsa04014 9 5.590e-05 1.910e-04
56 Non-small cell lung cancer hsa05223 5 6.681e-05 2.218e-04
57 Natural killer cell mediated cytotoxicity hsa04650 7 7.060e-05 2.329e-04
58 Thyroid cancer hsa05216 4 7.063e-05 2.330e-04
59 Acute myeloid leukemia hsa05221 5 7.268e-05 2.382e-04
60 Chemokine signaling pathway hsa04062 8 8.662e-05 2.756e-04
61 mTOR signaling pathway hsa04150 5 9.268e-05 2.909e-04
62 Wnt signaling pathway hsa04310 7 9.706e-05 3.025e-04
63 Amoebiasis hsa05146 6 1.697e-04 4.725e-04
64 Allograft rejection hsa05330 4 1.816e-04 4.988e-04
65 Graft-versus-host disease hsa05332 4 2.691e-04 6.763e-04
66 Thyroid hormone signaling pathway hsa04919 6 2.735e-04 6.852e-04
67 Intestinal immune network for IgA production hsa04672 4 4.518e-04 1.016e-03
68 Salmonella infection hsa05132 5 4.927e-04 1.092e-03
69 ErbB signaling pathway hsa04012 5 5.192e-04 1.138e-03
70 Signaling pathways regulating pluripotency of stem cells hsa04550 6 7.271e-04 1.490e-03
71 Staphylococcus aureus infection hsa05150 4 8.142e-04 1.624e-03
72 VEGF signaling pathway hsa04370 4 1.195e-03 2.211e-03
73 Insulin resistance hsa04931 5 1.423e-03 2.549e-03
74 Sphingolipid signaling pathway hsa04071 5 2.165e-03 3.560e-03
75 Adherens junction hsa04520 4 2.299e-03 3.750e-03
76 TGF-beta signaling pathway hsa04350 4 3.799e-03 5.609e-03
77 Hematopoietic cell lineage hsa04640 4 4.300e-03 6.203e-03
78 Type I diabetes mellitus hsa04940 3 4.331e-03 6.242e-03
79 Oxytocin signaling pathway hsa04921 5 6.910e-03 9.261e-03
80 Amyotrophic lateral sclerosis (ALS) hsa05014 3 6.919e-03 9.270e-03
81 Mineral absorption hsa04978 3 6.919e-03 9.270e-03
82 Choline metabolism in cancer hsa05231 4 7.233e-03 9.637e-03
83 Autoimmune thyroid disease hsa05320 3 7.295e-03 9.703e-03
84 Legionellosis hsa05134 3 8.493e-03 1.102e-02
85 NOD-like receptor signaling pathway hsa04621 3 9.352e-03 1.198e-02
86 Cholinergic synapse hsa04725 4 9.985e-03 1.267e-02
87 Leukocyte transendothelial migration hsa04670 4 1.227e-02 1.515e-02
88 AMPK signaling pathway hsa04152 4 1.447e-02 1.753e-02
89 B cell receptor signaling pathway hsa04662 3 1.739e-02 2.059e-02
90 Dorso-ventral axis formation hsa04320 2 1.847e-02 2.171e-02
91 Asthma hsa05310 2 2.239e-02 2.581e-02
92 Phospholipase D signaling pathway hsa04072 4 2.303e-02 2.647e-02
93 GnRH signaling pathway hsa04912 3 3.171e-02 3.534e-02
94 Proteasome hsa03050 2 4.456e-02 4.850e-02

- Gene Ontology biological process terms

#DescriptionTerm ID# of overlapped genesP valueFDR
1 positive regulation of transcription from RNA polymerase II promoter GO:0045944 34 3.050e-21 1.568e-18
2 positive regulation of cell proliferation GO:0008284 27 1.124e-19 4.662e-17
3 anti-apoptosis GO:0006916 21 2.655e-18 8.716e-16
4 response to drug GO:0042493 22 2.436e-16 5.937e-14
5 response to hypoxia GO:0001666 18 5.031e-16 1.133e-13
6 negative regulation of cell proliferation GO:0008285 23 6.350e-16 1.390e-13
7 response to cytokine stimulus GO:0034097 12 2.009e-14 3.209e-12
8 response to organic cyclic compound GO:0014070 14 3.120e-14 4.758e-12
9 negative regulation of apoptotic process GO:0043066 19 8.166e-14 1.122e-11
10 negative regulation of transcription from RNA polymerase II promoter GO:0000122 22 6.862e-13 7.652e-11
11 cytokine-mediated signaling pathway GO:0019221 17 9.618e-13 1.024e-10
12 positive regulation of smooth muscle cell proliferation GO:0048661 9 1.002e-11 8.585e-10
13 positive regulation of protein phosphorylation GO:0001934 11 2.867e-11 2.165e-09
14 signal transduction GO:0007165 33 3.567e-11 2.615e-09
15 response to heat GO:0009408 9 9.120e-11 5.972e-09
16 angiogenesis GO:0001525 13 1.971e-10 1.179e-08
17 response to lipopolysaccharide GO:0032496 12 2.207e-10 1.301e-08
18 cellular response to interleukin-1 GO:0071347 7 2.513e-10 1.463e-08
19 response to estradiol stimulus GO:0032355 10 6.937e-10 3.482e-08
20 negative regulation of cell growth GO:0030308 11 7.031e-10 3.521e-08
21 response to peptide hormone stimulus GO:0043434 9 7.134e-10 3.550e-08
22 positive regulation of cell division GO:0051781 8 1.141e-09 5.227e-08
23 regulation of interferon-gamma-mediated signaling pathway GO:0060334 6 1.188e-09 5.421e-08
24 positive regulation of angiogenesis GO:0045766 9 1.693e-09 7.331e-08
25 interferon-gamma-mediated signaling pathway GO:0060333 9 2.216e-09 9.142e-08
26 positive regulation of nitric oxide biosynthetic process GO:0045429 7 2.564e-09 1.040e-07
27 platelet activation GO:0030168 13 4.855e-09 1.830e-07
28 positive regulation of peptidyl-serine phosphorylation GO:0033138 7 6.394e-09 2.270e-07
29 collagen catabolic process GO:0030574 6 7.804e-09 2.678e-07
30 response to glucocorticoid stimulus GO:0051384 9 1.055e-08 3.469e-07
31 response to corticosterone stimulus GO:0051412 6 1.434e-08 4.484e-07
32 JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 6 1.900e-08 5.658e-07
33 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 8 1.943e-08 5.756e-07
34 ovarian follicle development GO:0001541 7 2.455e-08 6.960e-07
35 response to progesterone stimulus GO:0032570 6 2.485e-08 7.019e-07
36 apoptotic process GO:0006915 20 2.598e-08 7.295e-07
37 type I interferon-mediated signaling pathway GO:0060337 8 2.846e-08 7.787e-07
38 response to mechanical stimulus GO:0009612 7 4.054e-08 1.050e-06
39 positive regulation of epithelial cell proliferation GO:0050679 7 4.054e-08 1.050e-06
40 JAK-STAT cascade GO:0007259 6 4.103e-08 1.060e-06
41 regulation of type I interferon-mediated signaling pathway GO:0060338 6 4.103e-08 1.060e-06
42 response to gamma radiation GO:0010332 6 5.190e-08 1.290e-06
43 positive regulation of apoptotic process GO:0043065 11 5.573e-08 1.362e-06
44 inflammatory response GO:0006954 13 5.935e-08 1.426e-06
45 positive regulation of transcription, DNA-dependent GO:0045893 17 7.672e-08 1.759e-06
46 organ regeneration GO:0031100 7 8.648e-08 1.941e-06
47 platelet degranulation GO:0002576 8 1.487e-07 3.000e-06
48 response to ethanol GO:0045471 8 2.392e-07 4.478e-06
49 positive regulation of MAPK cascade GO:0043410 7 2.476e-07 4.612e-06
50 response to insulin stimulus GO:0032868 7 3.141e-07 5.588e-06
51 blood coagulation GO:0007596 16 3.294e-07 5.811e-06
52 response to DNA damage stimulus GO:0006974 9 3.408e-07 5.986e-06
53 protein import into nucleus, translocation GO:0000060 5 4.032e-07 6.852e-06
54 cellular response to hypoxia GO:0071456 6 4.200e-07 7.087e-06
55 positive regulation of anti-apoptosis GO:0045768 6 4.200e-07 7.087e-06
56 regulation of cell cycle GO:0051726 7 4.417e-07 7.369e-06
57 cell cycle arrest GO:0007050 9 5.848e-07 9.168e-06
58 cell proliferation GO:0008283 13 5.916e-07 9.256e-06
59 positive regulation of interleukin-17 production GO:0032740 4 9.499e-07 1.350e-05
60 cell morphogenesis GO:0000902 6 1.010e-06 1.416e-05
61 vascular endothelial growth factor receptor signaling pathway GO:0048010 5 1.028e-06 1.430e-05
62 cell aging GO:0007569 5 1.028e-06 1.430e-05
63 female pregnancy GO:0007565 7 1.112e-06 1.524e-05
64 positive regulation of ERK1 and ERK2 cascade GO:0070374 7 1.470e-06 1.891e-05
65 response to radiation GO:0009314 5 1.543e-06 1.960e-05
66 lung development GO:0030324 7 1.609e-06 2.019e-05
67 positive regulation of endothelial cell proliferation GO:0001938 6 1.912e-06 2.301e-05
68 regulation of apoptotic process GO:0042981 10 2.149e-06 2.514e-05
69 positive regulation of mesenchymal cell proliferation GO:0002053 5 2.242e-06 2.604e-05
70 cellular response to tumor necrosis factor GO:0071356 5 2.242e-06 2.604e-05
71 positive regulation of blood vessel endothelial cell migration GO:0043536 4 2.831e-06 3.112e-05
72 regulation of transcription from RNA polymerase II promoter in response to oxidative stress GO:0043619 3 4.048e-06 4.053e-05
73 cellular response to amino acid stimulus GO:0071230 5 4.375e-06 4.305e-05
74 cellular response to lithium ion GO:0071285 4 5.088e-06 4.835e-05
75 response to estrogen stimulus GO:0043627 6 5.664e-06 5.265e-05
76 intracellular protein kinase cascade GO:0007243 7 6.273e-06 5.693e-05
77 humoral immune response GO:0006959 5 7.843e-06 6.658e-05
78 activation-induced cell death of T cells GO:0006924 3 8.051e-06 6.785e-05
79 induction of apoptosis GO:0006917 9 9.441e-06 7.677e-05
80 positive regulation of cell death GO:0010942 4 1.065e-05 8.391e-05
81 positive regulation of gene expression GO:0010628 7 1.156e-05 8.884e-05
82 positive regulation of cell migration GO:0030335 7 1.156e-05 8.884e-05
83 response to oxidative stress GO:0006979 7 1.314e-05 9.815e-05
84 negative regulation of inflammatory response GO:0050728 5 1.316e-05 9.832e-05
85 reactive oxygen species metabolic process GO:0072593 4 1.323e-05 9.878e-05
86 cell-cell signaling GO:0007267 10 1.396e-05 1.025e-04
87 positive regulation of cyclin-dependent protein kinase activity involved in G1/S GO:0031659 3 1.401e-05 1.027e-04
88 prostate gland growth GO:0060736 3 1.401e-05 1.027e-04
89 protein autophosphorylation GO:0046777 8 1.500e-05 1.080e-04
90 aging GO:0007568 7 1.583e-05 1.125e-04
91 response to bacterium GO:0009617 4 1.625e-05 1.150e-04
92 negative regulation of T cell proliferation GO:0042130 4 1.625e-05 1.150e-04
93 cellular response to lipopolysaccharide GO:0071222 5 1.671e-05 1.173e-04
94 induction of apoptosis by intracellular signals GO:0008629 5 1.874e-05 1.273e-04
95 immune response GO:0006955 12 1.940e-05 1.307e-04
96 positive regulation of cyclin-dependent protein kinase activity GO:0045737 3 2.230e-05 1.448e-04
97 positive regulation of protein kinase B signaling cascade GO:0051897 5 2.337e-05 1.497e-04
98 embryonic placenta development GO:0001892 4 2.836e-05 1.718e-04
99 response to cAMP GO:0051591 5 2.884e-05 1.740e-04
100 defense response to virus GO:0051607 5 2.884e-05 1.740e-04
101 positive regulation of chemokine biosynthetic process GO:0045080 3 3.326e-05 1.932e-04
102 mitotic cell cycle G1/S transition DNA damage checkpoint GO:0031571 3 3.326e-05 1.932e-04
103 response to tumor necrosis factor GO:0034612 4 3.356e-05 1.942e-04
104 protein phosphorylation GO:0006468 12 3.446e-05 1.983e-04
105 innate immune response GO:0045087 11 3.624e-05 2.036e-04
106 response to cold GO:0009409 4 3.943e-05 2.163e-04
107 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 4 3.943e-05 2.163e-04
108 negative regulation of transcription, DNA-dependent GO:0045892 12 4.102e-05 2.221e-04
109 neutrophil chemotaxis GO:0030593 4 4.602e-05 2.424e-04
110 lipopolysaccharide-mediated signaling pathway GO:0031663 4 4.602e-05 2.424e-04
111 response to amino acid stimulus GO:0043200 4 4.602e-05 2.424e-04
112 regulation of mitochondrial membrane permeability GO:0046902 3 4.725e-05 2.476e-04
113 negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433 5 5.138e-05 2.620e-04
114 response to antibiotic GO:0046677 4 5.338e-05 2.688e-04
115 proteolysis GO:0006508 14 5.452e-05 2.732e-04
116 regulation of inflammatory response GO:0050727 4 6.157e-05 2.973e-04
117 cellular response to fibroblast growth factor stimulus GO:0044344 3 6.462e-05 3.083e-04
118 negative regulation of hormone secretion GO:0046888 3 6.462e-05 3.083e-04
119 induction of positive chemotaxis GO:0050930 3 6.462e-05 3.083e-04
120 positive regulation of tumor necrosis factor production GO:0032760 4 7.063e-05 3.269e-04
121 positive regulation of cell adhesion GO:0045785 4 7.063e-05 3.269e-04
122 positive regulation of MAP kinase activity GO:0043406 4 8.062e-05 3.584e-04
123 positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 7 8.879e-05 3.840e-04
124 branching involved in ureteric bud morphogenesis GO:0001658 4 9.160e-05 3.943e-04
125 response to organic nitrogen GO:0010243 4 9.160e-05 3.943e-04
126 activation of pro-apoptotic gene products GO:0008633 4 9.160e-05 3.943e-04
127 negative regulation of macrophage derived foam cell differentiation GO:0010745 3 1.108e-04 4.514e-04
128 cellular iron ion homeostasis GO:0006879 5 1.167e-04 4.662e-04
129 positive regulation of B cell proliferation GO:0030890 4 1.168e-04 4.665e-04
130 intracellular receptor mediated signaling pathway GO:0030522 4 1.168e-04 4.665e-04
131 response to glucose stimulus GO:0009749 5 1.351e-04 5.172e-04
132 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 3 1.402e-04 5.312e-04
133 positive regulation of collagen biosynthetic process GO:0032967 3 1.402e-04 5.312e-04
134 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 5 1.451e-04 5.438e-04
135 response to toxin GO:0009636 5 1.557e-04 5.712e-04
136 male gonad development GO:0008584 5 1.557e-04 5.712e-04
137 negative regulation of epithelial cell proliferation GO:0050680 4 1.634e-04 5.910e-04
138 acute-phase response GO:0006953 4 1.634e-04 5.910e-04
139 mammary gland alveolus development GO:0060749 3 1.743e-04 6.188e-04
140 superoxide anion generation GO:0042554 3 1.743e-04 6.188e-04
141 response to copper ion GO:0046688 3 1.743e-04 6.188e-04
142 negative regulation of growth of symbiont in host GO:0044130 3 1.743e-04 6.188e-04
143 positive regulation of phosphatidylinositol 3-kinase cascade GO:0014068 4 1.816e-04 6.359e-04
144 positive regulation of fibroblast proliferation GO:0048146 4 2.012e-04 6.814e-04
145 G1 phase of mitotic cell cycle GO:0000080 4 2.012e-04 6.814e-04
146 B cell differentiation GO:0030183 4 2.012e-04 6.814e-04
147 negative regulation of cell differentiation GO:0045596 3 2.134e-04 7.106e-04
148 positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 3 2.134e-04 7.106e-04
149 negative regulation of mitotic cell cycle GO:0045930 3 2.134e-04 7.106e-04
150 positive regulation vascular endothelial growth factor production GO:0010575 3 2.134e-04 7.106e-04
151 response to stress GO:0006950 7 2.369e-04 7.655e-04
152 regulation of gene expression GO:0010468 4 2.449e-04 7.859e-04
153 cell surface receptor signaling pathway GO:0007166 7 2.459e-04 7.877e-04
154 decidualization GO:0046697 3 2.577e-04 8.164e-04
155 negative regulation of neuron apoptosis GO:0043524 5 2.631e-04 8.294e-04
156 in utero embryonic development GO:0001701 7 2.646e-04 8.328e-04
157 T cell homeostasis GO:0043029 3 3.075e-04 9.247e-04
158 endoplasmic reticulum unfolded protein response GO:0030968 5 3.152e-04 9.408e-04
159 chemotaxis GO:0006935 6 3.564e-04 1.031e-03
160 positive regulation of activated T cell proliferation GO:0042104 3 3.632e-04 1.043e-03
161 response to X-ray GO:0010165 3 3.632e-04 1.043e-03
162 regulation of nitric-oxide synthase activity GO:0050999 3 3.632e-04 1.043e-03
163 regulation of protein stability GO:0031647 3 3.632e-04 1.043e-03
164 regulation of catalytic activity GO:0050790 4 3.833e-04 1.085e-03
165 cellular response to UV GO:0034644 3 4.249e-04 1.164e-03
166 positive regulation of vasoconstriction GO:0045907 3 4.930e-04 1.303e-03
167 positive chemotaxis GO:0050918 3 4.930e-04 1.303e-03
168 positive regulation of intracellular protein kinase cascade GO:0010740 2 5.467e-04 1.400e-03
169 STAT protein import into nucleus GO:0007262 2 5.467e-04 1.400e-03
170 negative regulation of B cell apoptosis GO:0002903 2 5.467e-04 1.400e-03
171 positive regulation of interleukin-23 production GO:0032747 2 5.467e-04 1.400e-03
172 negative regulation of skeletal muscle tissue development GO:0048642 2 5.467e-04 1.400e-03
173 mRNA transcription from RNA polymerase II promoter GO:0042789 2 5.467e-04 1.400e-03
174 response to peptidoglycan GO:0032494 2 5.467e-04 1.400e-03
175 tissue remodeling GO:0048771 2 5.467e-04 1.400e-03
176 positive regulation of mast cell chemotaxis GO:0060754 2 5.467e-04 1.400e-03
177 response to nicotine GO:0035094 3 5.678e-04 1.441e-03
178 positive regulation of reactive oxygen species metabolic process GO:2000379 3 5.678e-04 1.441e-03
179 negative regulation of DNA replication GO:0008156 3 5.678e-04 1.441e-03
180 regulation of protein phosphorylation GO:0001932 3 5.678e-04 1.441e-03
181 release of cytochrome c from mitochondria GO:0001836 3 5.678e-04 1.441e-03
182 regulation of angiogenesis GO:0045765 3 5.678e-04 1.441e-03
183 cellular response to mechanical stimulus GO:0071260 4 5.702e-04 1.443e-03
184 peptidyl-tyrosine phosphorylation GO:0018108 4 5.702e-04 1.443e-03
185 regulation of cell shape GO:0008360 5 6.054e-04 1.510e-03
186 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 4 6.142e-04 1.521e-03
187 positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 3 6.494e-04 1.588e-03
188 positive regulation of cell differentiation GO:0045597 3 6.494e-04 1.588e-03
189 inner ear development GO:0048839 3 6.494e-04 1.588e-03
190 cell differentiation GO:0030154 12 6.589e-04 1.606e-03
191 regulation of cyclin-dependent protein kinase activity GO:0000079 4 6.605e-04 1.607e-03
192 cellular component movement GO:0006928 5 7.019e-04 1.680e-03
193 elevation of cytosolic calcium ion concentration GO:0007204 5 7.365e-04 1.738e-03
194 positive regulation of NF-kappaB transcription factor activity GO:0051092 5 7.365e-04 1.738e-03
195 regulation of cell proliferation GO:0042127 5 7.365e-04 1.738e-03
196 positive regulation of phosphorylation GO:0042327 3 7.381e-04 1.739e-03
197 positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 3 7.381e-04 1.739e-03
198 response to virus GO:0009615 6 7.541e-04 1.769e-03
199 cellular response to insulin stimulus GO:0032869 4 7.605e-04 1.779e-03
200 regulation of blood pressure GO:0008217 4 7.605e-04 1.779e-03
201 organ morphogenesis GO:0009887 5 7.724e-04 1.801e-03
202 G-protein coupled receptor signaling pathway GO:0007186 9 7.736e-04 1.803e-03
203 G1/S transition of mitotic cell cycle GO:0000082 6 7.819e-04 1.814e-03
204 negative regulation of lipid storage GO:0010888 2 8.161e-04 1.876e-03
205 response to interleukin-4 GO:0070670 2 8.161e-04 1.876e-03
206 negative regulation of focal adhesion assembly GO:0051895 2 8.161e-04 1.876e-03
207 positive regulation of synaptic plasticity GO:0031915 2 8.161e-04 1.876e-03
208 signal transduction by p53 class mediator resulting in induction of apoptosis GO:0072332 2 8.161e-04 1.876e-03
209 positive regulation of isotype switching to IgG isotypes GO:0048304 2 8.161e-04 1.876e-03
210 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 2 8.161e-04 1.876e-03
211 positive regulation of DNA biosynthetic process GO:2000573 2 8.161e-04 1.876e-03
212 positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 2 8.161e-04 1.876e-03
213 positive regulation of interleukin-12 biosynthetic process GO:0045084 2 8.161e-04 1.876e-03
214 positive regulation of vascular permeability GO:0043117 2 8.161e-04 1.876e-03
215 salivary gland morphogenesis GO:0007435 2 8.161e-04 1.876e-03
216 positive regulation of histone deacetylation GO:0031065 2 8.161e-04 1.876e-03
217 negative regulation of phosphorylation GO:0042326 3 8.342e-04 1.907e-03
218 negative regulation of DNA binding GO:0043392 3 8.342e-04 1.907e-03
219 protein kinase B signaling cascade GO:0043491 3 9.378e-04 2.077e-03
220 regulation of immune response GO:0050776 5 1.015e-03 2.204e-03
221 response to wounding GO:0009611 4 1.056e-03 2.277e-03
222 regulation of growth GO:0040008 4 1.124e-03 2.378e-03
223 positive regulation of fatty acid beta-oxidation GO:0032000 2 1.137e-03 2.394e-03
224 negative regulation of interleukin-12 production GO:0032695 2 1.137e-03 2.394e-03
225 positive regulation of immunoglobulin secretion GO:0051024 2 1.137e-03 2.394e-03
226 regulation of neuron projection development GO:0010975 2 1.137e-03 2.394e-03
227 negative regulation of neuroblast proliferation GO:0007406 2 1.137e-03 2.394e-03
228 endothelial cell chemotaxis GO:0035767 2 1.137e-03 2.394e-03
229 negative regulation of cholesterol storage GO:0010887 2 1.137e-03 2.394e-03
230 stem cell development GO:0048864 2 1.137e-03 2.394e-03
231 platelet dense granule organization GO:0060155 2 1.137e-03 2.394e-03
232 response to molecule of bacterial origin GO:0002237 2 1.137e-03 2.394e-03
233 negative regulation of calcium ion transport GO:0051926 2 1.137e-03 2.394e-03
234 negative regulation of epithelial cell proliferation involved in prostate gland development GO:0060770 2 1.137e-03 2.394e-03
235 fatty acid catabolic process GO:0009062 2 1.137e-03 2.394e-03
236 negative regulation of release of cytochrome c from mitochondria GO:0090201 2 1.137e-03 2.394e-03
237 negative regulation of protein phosphorylation GO:0001933 3 1.169e-03 2.448e-03
238 T cell differentiation in thymus GO:0033077 3 1.169e-03 2.448e-03
239 cell maturation GO:0048469 3 1.297e-03 2.646e-03
240 cell death GO:0008219 6 1.301e-03 2.655e-03
241 transforming growth factor beta receptor signaling pathway GO:0007179 4 1.345e-03 2.719e-03
242 hemopoiesis GO:0030097 4 1.345e-03 2.719e-03
243 canonical Wnt receptor signaling pathway GO:0060070 4 1.425e-03 2.843e-03
244 wound healing GO:0042060 4 1.425e-03 2.843e-03
245 defense response to Gram-positive bacterium GO:0050830 3 1.433e-03 2.854e-03
246 response to laminar fluid shear stress GO:0034616 2 1.508e-03 2.970e-03
247 intermediate filament organization GO:0045109 2 1.508e-03 2.970e-03
248 branching involved in embryonic placenta morphogenesis GO:0060670 2 1.508e-03 2.970e-03
249 positive regulation of MHC class II biosynthetic process GO:0045348 2 1.508e-03 2.970e-03
250 regulation of cell growth GO:0001558 4 1.508e-03 2.970e-03
251 ossification GO:0001503 4 1.508e-03 2.970e-03
252 prostate gland development GO:0030850 2 1.508e-03 2.970e-03
253 positive regulation of acute inflammatory response GO:0002675 2 1.508e-03 2.970e-03
254 enzyme linked receptor protein signaling pathway GO:0007167 2 1.508e-03 2.970e-03
255 positive regulation of protein import into nucleus GO:0042307 2 1.508e-03 2.970e-03
256 S phase of mitotic cell cycle GO:0000084 5 1.541e-03 3.021e-03
257 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 4 1.595e-03 3.096e-03
258 cellular response to hormone stimulus GO:0032870 3 1.731e-03 3.293e-03
259 response to interleukin-1 GO:0070555 3 1.731e-03 3.293e-03
260 metabolic process GO:0008152 7 1.925e-03 3.571e-03
261 defense response to protozoan GO:0042832 2 1.930e-03 3.576e-03
262 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 2 1.930e-03 3.576e-03
263 lymphocyte chemotaxis GO:0048247 2 1.930e-03 3.576e-03
264 negative regulation of nitric oxide biosynthetic process GO:0045019 2 1.930e-03 3.576e-03
265 response to caffeine GO:0031000 2 1.930e-03 3.576e-03
266 negative regulation of transcription by competitive promoter binding GO:0010944 2 1.930e-03 3.576e-03
267 replicative senescence GO:0090399 2 1.930e-03 3.576e-03
268 negative regulation of cell-cell adhesion GO:0022408 2 1.930e-03 3.576e-03
269 negative regulation of immune response GO:0050777 2 1.930e-03 3.576e-03
270 prostate gland epithelium morphogenesis GO:0060740 2 1.930e-03 3.576e-03
271 3'-UTR-mediated mRNA stabilization GO:0070935 2 1.930e-03 3.576e-03
272 fibroblast growth factor receptor signaling pathway GO:0008543 5 1.939e-03 3.590e-03
273 lactation GO:0007595 3 2.066e-03 3.771e-03
274 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 4 2.080e-03 3.788e-03
275 gene expression GO:0010467 12 2.112e-03 3.832e-03
276 cellular response to organic cyclic compound GO:0071407 3 2.248e-03 4.024e-03
277 regulation of mitochondrial membrane potential GO:0051881 2 2.401e-03 4.218e-03
278 negative regulation of androgen receptor signaling pathway GO:0060766 2 2.401e-03 4.218e-03
279 branching involved in salivary gland morphogenesis GO:0060445 2 2.401e-03 4.218e-03
280 cellular homeostasis GO:0019725 2 2.401e-03 4.218e-03
281 negative regulation of blood vessel endothelial cell migration GO:0043537 2 2.401e-03 4.218e-03
282 negative thymic T cell selection GO:0045060 2 2.401e-03 4.218e-03
283 cell migration involved in sprouting angiogenesis GO:0002042 2 2.401e-03 4.218e-03
284 organ induction GO:0001759 2 2.401e-03 4.218e-03
285 negative regulation of appetite GO:0032099 2 2.401e-03 4.218e-03
286 neural crest cell migration GO:0001755 3 2.439e-03 4.272e-03
287 interspecies interaction between organisms GO:0044419 8 2.540e-03 4.402e-03
288 embryonic limb morphogenesis GO:0030326 3 2.639e-03 4.541e-03
289 phosphorylation GO:0016310 3 2.639e-03 4.541e-03
290 fat cell differentiation GO:0045444 3 2.639e-03 4.541e-03
291 lipoprotein metabolic process GO:0042157 3 2.850e-03 4.829e-03
292 epidermis development GO:0008544 4 2.918e-03 4.921e-03
293 anion transport GO:0006820 2 2.920e-03 4.922e-03
294 negative regulation of B cell proliferation GO:0030889 2 2.920e-03 4.922e-03
295 regulation of sodium ion transport GO:0002028 2 2.920e-03 4.922e-03
296 macrophage differentiation GO:0030225 2 2.920e-03 4.922e-03
297 regulation of ERK1 and ERK2 cascade GO:0070372 2 2.920e-03 4.922e-03
298 macrophage chemotaxis GO:0048246 2 2.920e-03 4.922e-03
299 positive regulation of nitric-oxide synthase activity GO:0051000 2 2.920e-03 4.922e-03
300 epidermal growth factor receptor signaling pathway GO:0007173 5 2.955e-03 4.967e-03
301 positive regulation of T cell proliferation GO:0042102 3 3.071e-03 5.125e-03
302 regulation of cell adhesion GO:0030155 3 3.302e-03 5.428e-03
303 response to hydrogen peroxide GO:0042542 3 3.302e-03 5.428e-03
304 Leydig cell differentiation GO:0033327 2 3.486e-03 5.644e-03
305 surfactant homeostasis GO:0043129 2 3.486e-03 5.644e-03
306 elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GO:0051482 2 3.486e-03 5.644e-03
307 positive regulation of peptidyl-threonine phosphorylation GO:0010800 2 3.486e-03 5.644e-03
308 response to fatty acid GO:0070542 2 3.486e-03 5.644e-03
309 labyrinthine layer blood vessel development GO:0060716 2 3.486e-03 5.644e-03
310 hypothalamus development GO:0021854 2 3.486e-03 5.644e-03
311 endothelial cell proliferation GO:0001935 2 3.486e-03 5.644e-03
312 positive regulation of cellular protein metabolic process GO:0032270 2 3.486e-03 5.644e-03
313 positive regulation of cellular component movement GO:0051272 2 3.486e-03 5.644e-03
314 positive regulation of smooth muscle contraction GO:0045987 2 3.486e-03 5.644e-03
315 response to ionizing radiation GO:0010212 3 4.057e-03 6.381e-03
316 intracellular signal transduction GO:0035556 7 4.084e-03 6.419e-03
317 B cell proliferation GO:0042100 2 4.100e-03 6.430e-03
318 monocyte chemotaxis GO:0002548 2 4.100e-03 6.430e-03
319 androgen metabolic process GO:0008209 2 4.100e-03 6.430e-03
320 ventricular septum development GO:0003281 2 4.100e-03 6.430e-03
321 mammary gland epithelial cell differentiation GO:0060644 2 4.100e-03 6.430e-03
322 positive regulation of osteoblast differentiation GO:0045669 3 4.331e-03 6.718e-03
323 steroid hormone mediated signaling pathway GO:0043401 2 4.760e-03 7.237e-03
324 response to growth factor stimulus GO:0070848 2 4.760e-03 7.237e-03
325 response to iron ion GO:0010039 2 4.760e-03 7.237e-03
326 negative regulation of ossification GO:0030279 2 4.760e-03 7.237e-03
327 response to pH GO:0009268 2 4.760e-03 7.237e-03
328 cellular response to extracellular stimulus GO:0031668 2 4.760e-03 7.237e-03
329 cellular response to vascular endothelial growth factor stimulus GO:0035924 2 4.760e-03 7.237e-03
330 cellular response to retinoic acid GO:0071300 3 4.910e-03 7.427e-03
331 heart development GO:0007507 5 4.984e-03 7.512e-03
332 multicellular organismal development GO:0007275 15 5.274e-03 7.870e-03
333 defense response to bacterium GO:0042742 4 5.433e-03 8.064e-03
334 positive regulation of chemokine production GO:0032722 2 5.466e-03 8.103e-03
335 defense response to Gram-negative bacterium GO:0050829 2 5.466e-03 8.103e-03
336 digestive tract morphogenesis GO:0048546 2 5.466e-03 8.103e-03
337 cellular response to glucose stimulus GO:0071333 2 5.466e-03 8.103e-03
338 positive regulation of cell cycle arrest GO:0071158 2 5.466e-03 8.103e-03
339 induction of apoptosis via death domain receptors GO:0008625 2 5.466e-03 8.103e-03
340 negative regulation of protein kinase activity GO:0006469 3 5.534e-03 8.168e-03
341 proton transport GO:0015992 3 5.863e-03 8.580e-03
342 negative regulation of gene expression GO:0010629 3 5.863e-03 8.580e-03
343 cell growth GO:0016049 3 6.204e-03 9.001e-03
344 muscle cell homeostasis GO:0046716 2 6.216e-03 9.001e-03
345 positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 2 6.216e-03 9.001e-03
346 positive regulation of JAK-STAT cascade GO:0046427 2 6.216e-03 9.001e-03
347 neural tube closure GO:0001843 3 6.556e-03 9.398e-03
348 transcription from RNA polymerase II promoter GO:0006366 7 6.706e-03 9.582e-03
349 response to vitamin D GO:0033280 2 7.010e-03 9.940e-03
350 establishment of cell polarity GO:0030010 2 7.010e-03 9.940e-03
351 DNA methylation GO:0006306 2 7.010e-03 9.940e-03
352 nitric oxide metabolic process GO:0046209 2 7.010e-03 9.940e-03
353 activation of NF-kappaB-inducing kinase activity GO:0007250 2 7.010e-03 9.940e-03
354 homeostasis of number of cells within a tissue GO:0048873 2 7.010e-03 9.940e-03
355 negative regulation of cyclin-dependent protein kinase activity GO:0045736 2 7.010e-03 9.940e-03
356 vasculogenesis GO:0001570 3 7.295e-03 1.028e-02
357 MAPK cascade GO:0000165 3 7.295e-03 1.028e-02
358 response to calcium ion GO:0051592 3 7.295e-03 1.028e-02
359 cell migration GO:0016477 4 7.482e-03 1.048e-02
360 protein localization GO:0008104 3 7.682e-03 1.074e-02
361 protein dephosphorylation GO:0006470 4 7.737e-03 1.080e-02
362 reverse cholesterol transport GO:0043691 2 7.848e-03 1.093e-02
363 neuron fate commitment GO:0048663 2 7.848e-03 1.093e-02
364 regulation of sensory perception of pain GO:0051930 2 7.848e-03 1.093e-02
365 response to light stimulus GO:0009416 2 7.848e-03 1.093e-02
366 endothelial cell migration GO:0043542 2 7.848e-03 1.093e-02
367 positive regulation of epithelial to mesenchymal transition GO:0010718 2 7.848e-03 1.093e-02
368 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 2 7.848e-03 1.093e-02
369 chromosome organization GO:0051276 2 7.848e-03 1.093e-02
370 induction of apoptosis by extracellular signals GO:0008624 4 8.264e-03 1.135e-02
371 cytokinesis GO:0000910 3 8.493e-03 1.163e-02
372 O-glycan processing GO:0016266 3 8.493e-03 1.163e-02
373 leukocyte migration GO:0050900 4 8.536e-03 1.167e-02
374 response to hyperoxia GO:0055093 2 8.729e-03 1.190e-02
375 cellular response to ionizing radiation GO:0071479 2 8.729e-03 1.190e-02
376 cholesterol metabolic process GO:0008203 3 8.917e-03 1.212e-02
377 cell adhesion GO:0007155 10 9.085e-03 1.231e-02
378 small molecule metabolic process GO:0044281 15 9.191e-03 1.244e-02
379 positive regulation of cell growth GO:0030307 3 9.352e-03 1.264e-02
380 peptidyl-tyrosine dephosphorylation GO:0035335 3 9.352e-03 1.264e-02
381 negative regulation of fibroblast proliferation GO:0048147 2 9.651e-03 1.298e-02
382 neuron apoptosis GO:0051402 2 9.651e-03 1.298e-02
383 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 2 9.651e-03 1.298e-02
384 DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 2 9.651e-03 1.298e-02
385 response to inorganic substance GO:0010035 2 9.651e-03 1.298e-02
386 positive regulation of cytokine secretion GO:0050715 2 1.062e-02 1.406e-02
387 positive regulation of calcium ion transport GO:0051928 2 1.062e-02 1.406e-02
388 pituitary gland development GO:0021983 2 1.062e-02 1.406e-02
389 negative regulation of insulin receptor signaling pathway GO:0046627 2 1.062e-02 1.406e-02
390 negative regulation of tumor necrosis factor production GO:0032720 2 1.162e-02 1.518e-02
391 cellular response to calcium ion GO:0071277 2 1.162e-02 1.518e-02
392 cellular response to drug GO:0035690 2 1.162e-02 1.518e-02
393 eating behavior GO:0042755 2 1.162e-02 1.518e-02
394 spleen development GO:0048536 2 1.162e-02 1.518e-02
395 negative regulation of smooth muscle cell proliferation GO:0048662 2 1.162e-02 1.518e-02
396 negative regulation of cell migration GO:0030336 3 1.172e-02 1.529e-02
397 activation of signaling protein activity involved in unfolded protein response GO:0006987 3 1.172e-02 1.529e-02
398 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 3 1.172e-02 1.529e-02
399 positive regulation of cell-substrate adhesion GO:0010811 2 1.267e-02 1.635e-02
400 embryonic forelimb morphogenesis GO:0035115 2 1.267e-02 1.635e-02
401 response to testosterone stimulus GO:0033574 2 1.267e-02 1.635e-02
402 cellular calcium ion homeostasis GO:0006874 3 1.275e-02 1.644e-02
403 regulation of sequence-specific DNA binding transcription factor activity GO:0051090 3 1.275e-02 1.644e-02
404 peptidyl-threonine phosphorylation GO:0018107 2 1.375e-02 1.755e-02
405 epithelial to mesenchymal transition GO:0001837 2 1.375e-02 1.755e-02
406 steroid biosynthetic process GO:0006694 2 1.375e-02 1.755e-02
407 hair follicle morphogenesis GO:0031069 2 1.487e-02 1.875e-02
408 vasculature development GO:0001944 2 1.487e-02 1.875e-02
409 adrenal gland development GO:0030325 2 1.487e-02 1.875e-02
410 embryonic hindlimb morphogenesis GO:0035116 2 1.487e-02 1.875e-02
411 face morphogenesis GO:0060325 2 1.487e-02 1.875e-02
412 extracellular matrix organization GO:0030198 3 1.496e-02 1.885e-02
413 negative regulation of fat cell differentiation GO:0045599 2 1.603e-02 2.005e-02
414 germ cell development GO:0007281 2 1.603e-02 2.005e-02
415 Ras protein signal transduction GO:0007265 3 1.615e-02 2.018e-02
416 liver development GO:0001889 3 1.615e-02 2.018e-02
417 cell cycle checkpoint GO:0000075 4 1.648e-02 2.053e-02
418 branching morphogenesis of a tube GO:0048754 2 1.723e-02 2.133e-02
419 tumor necrosis factor-mediated signaling pathway GO:0033209 2 1.723e-02 2.133e-02
420 developmental growth GO:0048589 2 1.723e-02 2.133e-02
421 phosphatidylinositol-mediated signaling GO:0048015 3 1.802e-02 2.219e-02
422 cell-cell adhesion GO:0016337 3 1.802e-02 2.219e-02
423 blood vessel remodeling GO:0001974 2 1.847e-02 2.268e-02
424 regulation of protein localization GO:0032880 2 1.847e-02 2.268e-02
425 erythrocyte differentiation GO:0030218 2 1.847e-02 2.268e-02
426 neural tube development GO:0021915 2 1.847e-02 2.268e-02
427 response to axon injury GO:0048678 2 1.847e-02 2.268e-02
428 oxidation-reduction process GO:0055114 4 1.867e-02 2.286e-02
429 toll-like receptor 4 signaling pathway GO:0034142 3 1.934e-02 2.357e-02
430 patterning of blood vessels GO:0001569 2 1.974e-02 2.401e-02
431 negative regulation of osteoblast differentiation GO:0045668 2 1.974e-02 2.401e-02
432 Toll signaling pathway GO:0008063 3 2.001e-02 2.429e-02
433 insulin receptor signaling pathway GO:0008286 4 2.054e-02 2.484e-02
434 metanephros development GO:0001656 2 2.105e-02 2.539e-02
435 protein polymerization GO:0051258 2 2.105e-02 2.539e-02
436 positive regulation of interleukin-6 production GO:0032755 2 2.105e-02 2.539e-02
437 response to activity GO:0014823 2 2.105e-02 2.539e-02
438 negative regulation of Wnt receptor signaling pathway GO:0030178 2 2.105e-02 2.539e-02
439 lipid metabolic process GO:0006629 5 2.129e-02 2.564e-02
440 thymus development GO:0048538 2 2.239e-02 2.683e-02
441 actin filament organization GO:0007015 2 2.239e-02 2.683e-02
442 behavior GO:0007610 2 2.377e-02 2.829e-02
443 mesoderm development GO:0007498 2 2.377e-02 2.829e-02
444 positive regulation of cAMP biosynthetic process GO:0030819 2 2.377e-02 2.829e-02
445 response to nutrient GO:0007584 3 2.511e-02 2.971e-02
446 growth GO:0040007 2 2.518e-02 2.979e-02
447 positive regulation of DNA replication GO:0045740 2 2.662e-02 3.137e-02
448 inhibition of adenylate cyclase activity by G-protein signaling pathway GO:0007193 2 2.662e-02 3.137e-02
449 steroid metabolic process GO:0008202 3 2.914e-02 3.399e-02
450 circadian rhythm GO:0007623 2 2.961e-02 3.449e-02
451 bile acid metabolic process GO:0008206 2 2.961e-02 3.449e-02
452 activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 2 2.961e-02 3.449e-02
453 ureteric bud development GO:0001657 2 3.115e-02 3.609e-02
454 mitotic cell cycle GO:0000278 6 3.250e-02 3.747e-02
455 electron transport chain GO:0022900 2 3.272e-02 3.770e-02
456 embryonic digit morphogenesis GO:0042733 2 3.272e-02 3.770e-02
457 positive regulation of inflammatory response GO:0050729 2 3.272e-02 3.770e-02
458 spermatogenesis GO:0007283 6 3.336e-02 3.838e-02
459 nervous system development GO:0007399 7 3.390e-02 3.894e-02
460 endocrine pancreas development GO:0031018 2 3.433e-02 3.938e-02
461 anatomical structure morphogenesis GO:0009653 3 3.439e-02 3.944e-02
462 heart looping GO:0001947 2 3.596e-02 4.109e-02
463 G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 2 3.596e-02 4.109e-02
464 activation of MAPKK activity GO:0000186 2 3.762e-02 4.280e-02
465 response to organic substance GO:0010033 2 3.931e-02 4.455e-02
466 T cell activation GO:0042110 2 3.931e-02 4.455e-02
467 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway GO:0035872 2 3.931e-02 4.455e-02
468 skin development GO:0043588 2 3.931e-02 4.455e-02
469 regulation of cell migration GO:0030334 2 4.103e-02 4.632e-02
470 energy reserve metabolic process GO:0006112 3 4.211e-02 4.745e-02
471 response to retinoic acid GO:0032526 2 4.278e-02 4.814e-02
472 cell cycle GO:0007049 7 4.389e-02 4.925e-02