| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | CFB | Activation | 22169226 |
| 2 | STAT3 | CFLAR | Unknown | 18222423 |
| 3 | STAT3 | COPS5 | Unknown | 21689417 |
| 4 | STAT3 | HGF | Activation | 12168776 |
| 5 | STAT3 | HGF | Unknown | 23954444 |
| 6 | STAT3 | MMP1 | Unknown | 16205632; 17460772; 21410405 |
| 7 | STAT3 | MMP10 | Unknown | 16205632 |
| 8 | STAT3 | MMP14 | Unknown | 14673954 |
| 9 | STAT3 | MMP2 | Activation | 17533737; 19284568; 20069389 |
| 10 | STAT3 | MMP2 | Repression | 17533737 |
| 11 | STAT3 | MMP2 | Unknown | 16540670 |
| 12 | STAT3 | MMP3 | Unknown | 17460772; 23967200 |
| 13 | STAT3 | MMP7 | Activation | 18411043 |
| 14 | STAT3 | MMP7 | Repression | 20939893 |
| 15 | STAT3 | MMP9 | Repression | 20067773 |
| 16 | STAT3 | PROS1 | Unknown | 16840717 |
| 17 | STAT3 | USP7 | Repression | 22750444 |