| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | AKT1 | Unknown | 16007214 |
| 2 | STAT3 | CCL2 | Activation | 24429361 |
| 3 | STAT3 | CFLAR | Unknown | 18222423 |
| 4 | STAT3 | FAS | Activation | 15223310 |
| 5 | STAT3 | FAS | Repression | 16651438; 22313388 |
| 6 | STAT3 | FOS | Activation | 12600988; 14737107; 17204573 |
| 7 | STAT3 | ICAM1 | Unknown | 23690481; 8675499 |
| 8 | STAT3 | IL6 | Activation | 10391682; 18765795; 20930550; 22547075; 22927445 |
| 9 | STAT3 | IL6 | Repression | 18616672 |
| 10 | STAT3 | IL6 | Unknown | 22105366; 22363173 |
| 11 | STAT3 | JUNB | Activation | 17204573 |
| 12 | STAT3 | MMP14 | Unknown | 14673954 |
| 13 | STAT3 | MMP3 | Unknown | 17460772; 23967200 |
| 14 | STAT3 | MMP9 | Repression | 20067773 |
| 15 | STAT3 | PTGS2 | Activation | 20145033 |
| 16 | STAT3 | PTGS2 | Unknown | 21172343 |
| 17 | STAT3 | SOCS3 | Activation | 11788008; 15184887; 19332118; 20357037; 22179221 |
| 18 | STAT3 | SOCS3 | Unknown | 23335796 |