| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | AKT1 | Unknown | 16007214 |
| 2 | STAT3 | BCL6 | Activation | 20228272; 23716595 |
| 3 | STAT3 | CCND1 | Activation | 16651438; 19880237; 19926637; 21435102; 22218594 |
| 4 | STAT3 | CCND1 | Repression | 19880237; 22313388 |
| 5 | STAT3 | CCND1 | Unknown | 12147685; 15469392; 16384639; 16510571; 18184402; 20332458; 21172343; 21344490 |
| 6 | STAT3 | CCND2 | Unknown | 12147685 |
| 7 | STAT3 | CDKN1A | Activation | 10023678; 15286705 |
| 8 | STAT3 | CDKN1A | Unknown | 16923815; 18320073; 20654581 |
| 9 | STAT3 | CDKN1B | Unknown | 18320073 |
| 10 | STAT3 | EGFR | Activation | 21590492; 23504318 |
| 11 | STAT3 | IL10 | Activation | 12817009; 18765795 |
| 12 | STAT3 | IL10 | Unknown | 10903771; 15034082; 17404037; 18403020; 19124156 |
| 13 | STAT3 | IL6 | Activation | 10391682; 18765795; 20930550; 22547075; 22927445 |
| 14 | STAT3 | IL6 | Repression | 18616672 |
| 15 | STAT3 | IL6 | Unknown | 22105366; 22363173 |
| 16 | STAT3 | NLK | Unknown | 15764709 |
| 17 | STAT3 | PTEN | Activation | 22055460 |
| 18 | STAT3 | S1PR1 | Activation | 21102457 |
| 19 | STAT3 | STK11 | Unknown | 24913037 |
| 20 | STAT3 | TGFB1 | Activation | 16474852 |
| 21 | STAT3 | USP7 | Repression | 22750444 |