| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | AKT1 | Unknown | 16007214 |
| 2 | STAT3 | CCL2 | Activation | 24429361 |
| 3 | STAT3 | CFLAR | Unknown | 18222423 |
| 4 | STAT3 | CXCL8 | Unknown | 17726017 |
| 5 | STAT3 | FAS | Activation | 15223310 |
| 6 | STAT3 | FAS | Repression | 16651438; 22313388 |
| 7 | STAT3 | FOS | Activation | 12600988; 14737107; 17204573 |
| 8 | STAT3 | IFNG | Repression | 18616672 |
| 9 | STAT3 | IL10 | Activation | 12817009; 18765795 |
| 10 | STAT3 | IL10 | Unknown | 10903771; 15034082; 17404037; 18403020; 19124156 |
| 11 | STAT3 | IL2 | Activation | 18550668 |
| 12 | STAT3 | IL6 | Activation | 10391682; 18765795; 20930550; 22547075; 22927445 |
| 13 | STAT3 | IL6 | Repression | 18616672 |
| 14 | STAT3 | IL6 | Unknown | 22105366; 22363173 |
| 15 | STAT3 | MYD88 | Unknown | 12244150 |
| 16 | STAT3 | TGFB1 | Activation | 16474852 |