| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | CCL2 | Activation | 24429361 |
| 2 | STAT3 | FAS | Activation | 15223310 |
| 3 | STAT3 | FAS | Repression | 16651438; 22313388 |
| 4 | STAT3 | ICAM1 | Unknown | 23690481; 8675499 |
| 5 | STAT3 | IFNG | Repression | 18616672 |
| 6 | STAT3 | IL10 | Activation | 12817009; 18765795 |
| 7 | STAT3 | IL10 | Unknown | 10903771; 15034082; 17404037; 18403020; 19124156 |
| 8 | STAT3 | IL1RN | Activation | 20032313 |
| 9 | STAT3 | IL6 | Activation | 10391682; 18765795; 20930550; 22547075; 22927445 |
| 10 | STAT3 | IL6 | Repression | 18616672 |
| 11 | STAT3 | IL6 | Unknown | 22105366; 22363173 |
| 12 | STAT3 | JAK2 | Activation | 17151100 |
| 13 | STAT3 | JAK2 | Unknown | 19783654 |
| 14 | STAT3 | LEP | Activation | 18242580; 19492417 |
| 15 | STAT3 | MMP2 | Activation | 17533737; 19284568; 20069389 |
| 16 | STAT3 | MMP2 | Repression | 17533737 |
| 17 | STAT3 | MMP2 | Unknown | 16540670 |
| 18 | STAT3 | SALL4 | Activation | 19151334 |
| 19 | STAT3 | TWIST1 | Unknown | 17909010 |
| 20 | STAT3 | TWIST1 | Activation | 23623921 |
| 21 | STAT3 | TWIST1 | Unknown | 17909010 |