| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | AKT1 | Unknown | 16007214 |
| 2 | STAT3 | BCL2 | Activation | 15184887; 15805299; 18839277; 19926637; 21435102; 22504301 |
| 3 | STAT3 | BCL2 | Repression | 22313388 |
| 4 | STAT3 | BCL2 | Unknown | 18320073; 20043094; 20446017; 21172343; 21344490; 21385902 |
| 5 | STAT3 | CDKN1A | Activation | 10023678; 15286705 |
| 6 | STAT3 | CDKN1A | Unknown | 16923815; 18320073; 20654581 |
| 7 | STAT3 | CDKN1B | Unknown | 18320073 |
| 8 | STAT3 | HSPB1 | Activation | 14715258 |
| 9 | STAT3 | ICAM1 | Unknown | 23690481; 8675499 |
| 10 | STAT3 | IFNG | Repression | 18616672 |
| 11 | STAT3 | IL10 | Activation | 12817009; 18765795 |
| 12 | STAT3 | IL10 | Unknown | 10903771; 15034082; 17404037; 18403020; 19124156 |
| 13 | STAT3 | MYC | Activation | 15184887; 17204573; 19259613 |
| 14 | STAT3 | MYC | Repression | 20067773; 22317895 |
| 15 | STAT3 | MYC | Unknown | 10464281; 15469392; 18184402; 20654581 |
| 16 | STAT3 | TP53 | Unknown | 20043094 |
| 17 | STAT3 | TYK2 | Repression | 18550668 |
| 18 | STAT3 | USP7 | Repression | 22750444 |