| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | AKT1 | Unknown | 16007214 |
| 2 | STAT3 | BCL2 | Activation | 15184887; 15805299; 18839277; 19926637; 21435102; 22504301 |
| 3 | STAT3 | BCL2 | Repression | 22313388 |
| 4 | STAT3 | BCL2 | Unknown | 18320073; 20043094; 20446017; 21172343; 21344490; 21385902 |
| 5 | STAT3 | BCL2L1 | Activation | 11369651; 15184887; 15805299; 16651438; 17880940; 20069389; 21435102 |
| 6 | STAT3 | BCL2L1 | Repression | 20067773 |
| 7 | STAT3 | BCL2L1 | Unknown | 15469392; 16384639; 18222423; 18790750; 20654581; 21172343; 21344490 |
| 8 | STAT3 | BIRC5 | Activation | 15184887; 16651438; 17880940; 19284568; 19880237 |
| 9 | STAT3 | BIRC5 | Unknown | 15469392; 20826784; 21344490 |
| 10 | STAT3 | CCND1 | Activation | 16651438; 19880237; 19926637; 21435102; 22218594 |
| 11 | STAT3 | CCND1 | Repression | 19880237; 22313388 |
| 12 | STAT3 | CCND1 | Unknown | 12147685; 15469392; 16384639; 16510571; 18184402; 20332458; 21172343; 21344490 |
| 13 | STAT3 | CCND2 | Unknown | 12147685 |
| 14 | STAT3 | CDKN1B | Unknown | 18320073 |
| 15 | STAT3 | CFLAR | Unknown | 18222423 |
| 16 | STAT3 | CHI3L1 | Activation | 21953450 |
| 17 | STAT3 | CRP | Activation | 12667216; 20978825; 23361365 |
| 18 | STAT3 | CRP | Unknown | 18292576 |
| 19 | STAT3 | FGF2 | Activation | 21418908; 23086340 |
| 20 | STAT3 | FGF2 | Unknown | 16540670 |
| 21 | STAT3 | HSPB1 | Activation | 14715258 |
| 22 | STAT3 | IFNAR1 | Activation | 18550668 |
| 23 | STAT3 | IFNG | Repression | 18616672 |
| 24 | STAT3 | IL1RN | Activation | 20032313 |
| 25 | STAT3 | IL6 | Activation | 10391682; 18765795; 20930550; 22547075; 22927445 |
| 26 | STAT3 | IL6 | Repression | 18616672 |
| 27 | STAT3 | IL6 | Unknown | 22105366; 22363173 |
| 28 | STAT3 | MCL1 | Activation | 15184887; 15805299; 16432172; 17880940; 19523441 |
| 29 | STAT3 | MCL1 | Repression | 22313388 |
| 30 | STAT3 | MCL1 | Unknown | 15469392; 16317687; 18790750; 19595668; 20654581; 22465052 |
| 31 | STAT3 | MMP1 | Unknown | 16205632; 17460772; 21410405 |
| 32 | STAT3 | MMP2 | Activation | 17533737; 19284568; 20069389 |
| 33 | STAT3 | MMP2 | Repression | 17533737 |
| 34 | STAT3 | MMP2 | Unknown | 16540670 |
| 35 | STAT3 | MUC1 | Activation | 17151127; 19578748; 21325207 |
| 36 | STAT3 | MYC | Activation | 15184887; 17204573; 19259613 |
| 37 | STAT3 | MYC | Repression | 20067773; 22317895 |
| 38 | STAT3 | MYC | Unknown | 10464281; 15469392; 18184402; 20654581 |
| 39 | STAT3 | OSM | Activation | 10391682 |
| 40 | STAT3 | PRDM1 | Activation | 1702555 |
| 41 | STAT3 | PRDM1 | Unknown | 12953803 |
| 42 | STAT3 | PTPN6 | Repression | 14630083; 16825495; 21792937 |
| 43 | STAT3 | PTPN6 | Unknown | 15870198 |
| 44 | STAT3 | TIMP1 | Activation | 15161657 |
| 45 | STAT3 | TIMP1 | Unknown | 11918744; 15920698 |