| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | ABCA1 | Unknown | 19783654 |
| 2 | STAT3 | AKT1 | Unknown | 16007214 |
| 3 | STAT3 | CRP | Activation | 12667216; 20978825; 23361365 |
| 4 | STAT3 | CRP | Unknown | 18292576 |
| 5 | STAT3 | ESR2 | Activation | 21546410 |
| 6 | STAT3 | HP | Unknown | 17645497 |
| 7 | STAT3 | ICAM1 | Unknown | 23690481; 8675499 |
| 8 | STAT3 | IL1RN | Activation | 20032313 |
| 9 | STAT3 | IL6 | Activation | 10391682; 18765795; 20930550; 22547075; 22927445 |
| 10 | STAT3 | IL6 | Repression | 18616672 |
| 11 | STAT3 | IL6 | Unknown | 22105366; 22363173 |
| 12 | STAT3 | LEP | Activation | 18242580; 19492417 |
| 13 | STAT3 | MMP2 | Activation | 17533737; 19284568; 20069389 |
| 14 | STAT3 | MMP2 | Repression | 17533737 |
| 15 | STAT3 | MMP2 | Unknown | 16540670 |
| 16 | STAT3 | MMP9 | Repression | 20067773 |
| 17 | STAT3 | NOX1 | Unknown | 19834108 |
| 18 | STAT3 | TIMP1 | Activation | 15161657 |
| 19 | STAT3 | TIMP1 | Unknown | 11918744; 15920698 |
| 20 | STAT3 | UCP2 | Repression | 21344490 |