| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | AKT1 | Unknown | 16007214 |
| 2 | STAT3 | BCL2 | Activation | 15184887; 15805299; 18839277; 19926637; 21435102; 22504301 |
| 3 | STAT3 | BCL2 | Repression | 22313388 |
| 4 | STAT3 | BCL2 | Unknown | 18320073; 20043094; 20446017; 21172343; 21344490; 21385902 |
| 5 | STAT3 | CDKN1A | Activation | 10023678; 15286705 |
| 6 | STAT3 | CDKN1A | Unknown | 16923815; 18320073; 20654581 |
| 7 | STAT3 | CDKN1B | Unknown | 18320073 |
| 8 | STAT3 | CTGF | Repression | 21245987 |
| 9 | STAT3 | EGFR | Activation | 21590492; 23504318 |
| 10 | STAT3 | ESR2 | Activation | 21546410 |
| 11 | STAT3 | FAS | Activation | 15223310 |
| 12 | STAT3 | FAS | Repression | 16651438; 22313388 |
| 13 | STAT3 | FGF2 | Activation | 21418908; 23086340 |
| 14 | STAT3 | FGF2 | Unknown | 16540670 |
| 15 | STAT3 | HIF1A | Activation | 17597020; 18644974; 19265129 |
| 16 | STAT3 | HIF1A | Unknown | 23991099 |
| 17 | STAT3 | MMP9 | Repression | 20067773 |
| 18 | STAT3 | PTGS2 | Activation | 20145033 |
| 19 | STAT3 | PTGS2 | Unknown | 21172343 |
| 20 | STAT3 | TWIST1 | Unknown | 17909010 |
| 21 | STAT3 | TWIST1 | Activation | 23623921 |
| 22 | STAT3 | TWIST1 | Unknown | 17909010 |
| 23 | STAT3 | VEGFA | Unknown | 23104276 |
| 24 | STAT3 | VEGFA | Activation | 11960372; 15735682; 17169602; 17533737; 19284568; 19880237; 21278793; 21418908 |
| 25 | STAT3 | VEGFA | Repression | 17533737; 19880237; 22313388 |
| 26 | STAT3 | VEGFA | Unknown | 12824281; 16540670; 16899623; 17937859; 18184402; 18320073; 19020709; 20043094; 21172343; 21344490; 21731766; 25101566 |