| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | AKAP12 | Activation | 22584896 |
| 2 | STAT3 | AKT1 | Unknown | 16007214 |
| 3 | STAT3 | AR | Unknown | 23906537 |
| 4 | STAT3 | BCL2 | Activation | 15184887; 15805299; 18839277; 19926637; 21435102; 22504301 |
| 5 | STAT3 | BCL2 | Repression | 22313388 |
| 6 | STAT3 | BCL2 | Unknown | 18320073; 20043094; 20446017; 21172343; 21344490; 21385902 |
| 7 | STAT3 | BIRC5 | Activation | 15184887; 16651438; 17880940; 19284568; 19880237 |
| 8 | STAT3 | BIRC5 | Unknown | 15469392; 20826784; 21344490 |
| 9 | STAT3 | CCL2 | Activation | 24429361 |
| 10 | STAT3 | CCND1 | Activation | 16651438; 19880237; 19926637; 21435102; 22218594 |
| 11 | STAT3 | CCND1 | Repression | 19880237; 22313388 |
| 12 | STAT3 | CCND1 | Unknown | 12147685; 15469392; 16384639; 16510571; 18184402; 20332458; 21172343; 21344490 |
| 13 | STAT3 | CCND2 | Unknown | 12147685 |
| 14 | STAT3 | CDKN1A | Activation | 10023678; 15286705 |
| 15 | STAT3 | CDKN1A | Unknown | 16923815; 18320073; 20654581 |
| 16 | STAT3 | CDKN1B | Unknown | 18320073 |
| 17 | STAT3 | CFLAR | Unknown | 18222423 |
| 18 | STAT3 | CTGF | Repression | 21245987 |
| 19 | STAT3 | CYR61 | Unknown | 22401280 |
| 20 | STAT3 | EGFR | Activation | 21590492; 23504318 |
| 21 | STAT3 | FAS | Activation | 15223310 |
| 22 | STAT3 | FAS | Repression | 16651438; 22313388 |
| 23 | STAT3 | HIF1A | Activation | 17597020; 18644974; 19265129 |
| 24 | STAT3 | HIF1A | Unknown | 23991099 |
| 25 | STAT3 | ICAM1 | Unknown | 23690481; 8675499 |
| 26 | STAT3 | IL10 | Activation | 12817009; 18765795 |
| 27 | STAT3 | IL10 | Unknown | 10903771; 15034082; 17404037; 18403020; 19124156 |
| 28 | STAT3 | IL1RN | Activation | 20032313 |
| 29 | STAT3 | IL2 | Activation | 18550668 |
| 30 | STAT3 | IL6 | Activation | 10391682; 18765795; 20930550; 22547075; 22927445 |
| 31 | STAT3 | IL6 | Repression | 18616672 |
| 32 | STAT3 | IL6 | Unknown | 22105366; 22363173 |
| 33 | STAT3 | LEP | Activation | 18242580; 19492417 |
| 34 | STAT3 | LGALS3BP | Repression | 18594176 |
| 35 | STAT3 | MCL1 | Activation | 15184887; 15805299; 16432172; 17880940; 19523441 |
| 36 | STAT3 | MCL1 | Repression | 22313388 |
| 37 | STAT3 | MCL1 | Unknown | 15469392; 16317687; 18790750; 19595668; 20654581; 22465052 |
| 38 | STAT3 | MMP1 | Unknown | 16205632; 17460772; 21410405 |
| 39 | STAT3 | MMP10 | Unknown | 16205632 |
| 40 | STAT3 | MMP14 | Unknown | 14673954 |
| 41 | STAT3 | MMP2 | Activation | 17533737; 19284568; 20069389 |
| 42 | STAT3 | MMP2 | Repression | 17533737 |
| 43 | STAT3 | MMP2 | Unknown | 16540670 |
| 44 | STAT3 | MMP7 | Activation | 18411043 |
| 45 | STAT3 | MMP7 | Repression | 20939893 |
| 46 | STAT3 | MMP9 | Repression | 20067773 |
| 47 | STAT3 | MUC1 | Activation | 17151127; 19578748; 21325207 |
| 48 | STAT3 | PTGS2 | Activation | 20145033 |
| 49 | STAT3 | PTGS2 | Unknown | 21172343 |
| 50 | STAT3 | S100A11 | Activation | 24376686 |
| 51 | STAT3 | SHH | Activation | 22554932 |
| 52 | STAT3 | TIMP1 | Activation | 15161657 |
| 53 | STAT3 | TIMP1 | Unknown | 11918744; 15920698 |
| 54 | STAT3 | TWIST1 | Unknown | 17909010 |
| 55 | STAT3 | TWIST1 | Activation | 23623921 |
| 56 | STAT3 | TWIST1 | Unknown | 17909010 |
| 57 | STAT3 | VEGFA | Unknown | 23104276 |
| 58 | STAT3 | VEGFA | Activation | 11960372; 15735682; 17169602; 17533737; 19284568; 19880237; 21278793; 21418908 |
| 59 | STAT3 | VEGFA | Repression | 17533737; 19880237; 22313388 |
| 60 | STAT3 | VEGFA | Unknown | 12824281; 16540670; 16899623; 17937859; 18184402; 18320073; 19020709; 20043094; 21172343; 21344490; 21731766; 25101566 |