| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | ABCA1 | Unknown | 19783654 |
| 2 | STAT3 | AR | Unknown | 23906537 |
| 3 | STAT3 | CCL11 | Activation | 19265112 |
| 4 | STAT3 | CCL11 | Unknown | 20169197 |
| 5 | STAT3 | CCL2 | Activation | 24429361 |
| 6 | STAT3 | CRP | Activation | 12667216; 20978825; 23361365 |
| 7 | STAT3 | CRP | Unknown | 18292576 |
| 8 | STAT3 | ESR2 | Activation | 21546410 |
| 9 | STAT3 | HIF1A | Activation | 17597020; 18644974; 19265129 |
| 10 | STAT3 | HIF1A | Unknown | 23991099 |
| 11 | STAT3 | HSPB1 | Activation | 14715258 |
| 12 | STAT3 | ICAM1 | Unknown | 23690481; 8675499 |
| 13 | STAT3 | IL10 | Activation | 12817009; 18765795 |
| 14 | STAT3 | IL10 | Unknown | 10903771; 15034082; 17404037; 18403020; 19124156 |
| 15 | STAT3 | IL6 | Activation | 10391682; 18765795; 20930550; 22547075; 22927445 |
| 16 | STAT3 | IL6 | Repression | 18616672 |
| 17 | STAT3 | IL6 | Unknown | 22105366; 22363173 |
| 18 | STAT3 | LCAT | Unknown | 12032172 |
| 19 | STAT3 | LEP | Activation | 18242580; 19492417 |
| 20 | STAT3 | MMP2 | Activation | 17533737; 19284568; 20069389 |
| 21 | STAT3 | MMP2 | Repression | 17533737 |
| 22 | STAT3 | MMP2 | Unknown | 16540670 |
| 23 | STAT3 | MMP3 | Unknown | 17460772; 23967200 |
| 24 | STAT3 | MMP9 | Repression | 20067773 |
| 25 | STAT3 | UCP2 | Repression | 21344490 |