| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | BCL2 | Activation | 15184887; 15805299; 18839277; 19926637; 21435102; 22504301 |
| 2 | STAT3 | BCL2 | Repression | 22313388 |
| 3 | STAT3 | BCL2 | Unknown | 18320073; 20043094; 20446017; 21172343; 21344490; 21385902 |
| 4 | STAT3 | CRP | Activation | 12667216; 20978825; 23361365 |
| 5 | STAT3 | CRP | Unknown | 18292576 |
| 6 | STAT3 | EGFR | Activation | 21590492; 23504318 |
| 7 | STAT3 | F2R | Activation | 23504318 |
| 8 | STAT3 | FAS | Activation | 15223310 |
| 9 | STAT3 | FAS | Repression | 16651438; 22313388 |
| 10 | STAT3 | HIF1A | Activation | 17597020; 18644974; 19265129 |
| 11 | STAT3 | HIF1A | Unknown | 23991099 |
| 12 | STAT3 | IL1RN | Activation | 20032313 |
| 13 | STAT3 | IL6 | Activation | 10391682; 18765795; 20930550; 22547075; 22927445 |
| 14 | STAT3 | IL6 | Repression | 18616672 |
| 15 | STAT3 | IL6 | Unknown | 22105366; 22363173 |
| 16 | STAT3 | JAK2 | Activation | 17151100 |
| 17 | STAT3 | JAK2 | Unknown | 19783654 |
| 18 | STAT3 | MMP9 | Repression | 20067773 |
| 19 | STAT3 | PTGS2 | Activation | 20145033 |
| 20 | STAT3 | PTGS2 | Unknown | 21172343 |
| 21 | STAT3 | STS | Activation | 21331591 |