| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | CCL2 | Activation | 24429361 |
| 2 | STAT3 | FLT3 | Activation | 16418395 |
| 3 | STAT3 | ICAM1 | Unknown | 23690481; 8675499 |
| 4 | STAT3 | IFNAR1 | Activation | 18550668 |
| 5 | STAT3 | IFNG | Repression | 18616672 |
| 6 | STAT3 | IL2RA | Unknown | 10068671; 11368440; 24159173 |
| 7 | STAT3 | IL6 | Activation | 10391682; 18765795; 20930550; 22547075; 22927445 |
| 8 | STAT3 | IL6 | Repression | 18616672 |
| 9 | STAT3 | IL6 | Unknown | 22105366; 22363173 |
| 10 | STAT3 | IRF1 | Activation | 8647845 |
| 11 | STAT3 | IRF1 | Unknown | 10068671 |
| 12 | STAT3 | JAK2 | Activation | 17151100 |
| 13 | STAT3 | JAK2 | Unknown | 19783654 |
| 14 | STAT3 | MYD88 | Unknown | 12244150 |
| 15 | STAT3 | OAS1 | Repression | 18550668 |
| 16 | STAT3 | PTPN6 | Repression | 14630083; 16825495; 21792937 |
| 17 | STAT3 | PTPN6 | Unknown | 15870198 |
| 18 | STAT3 | SOCS1 | Activation | 14630083; 20003295; 20357037 |
| 19 | STAT3 | SOCS3 | Activation | 11788008; 15184887; 19332118; 20357037; 22179221 |
| 20 | STAT3 | SOCS3 | Unknown | 23335796 |
| 21 | STAT3 | STAT1 | Activation | 22693070 |
| 22 | STAT3 | TYK2 | Repression | 18550668 |