| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | AKT1 | Unknown | 16007214 |
| 2 | STAT3 | BCL2 | Activation | 15184887; 15805299; 18839277; 19926637; 21435102; 22504301 |
| 3 | STAT3 | BCL2 | Repression | 22313388 |
| 4 | STAT3 | BCL2 | Unknown | 18320073; 20043094; 20446017; 21172343; 21344490; 21385902 |
| 5 | STAT3 | BIRC5 | Activation | 15184887; 16651438; 17880940; 19284568; 19880237 |
| 6 | STAT3 | BIRC5 | Unknown | 15469392; 20826784; 21344490 |
| 7 | STAT3 | CDKN1B | Unknown | 18320073 |
| 8 | STAT3 | COPS5 | Unknown | 21689417 |
| 9 | STAT3 | CTGF | Repression | 21245987 |
| 10 | STAT3 | DDIT3 | Repression | 23288901 |
| 11 | STAT3 | EGFR | Activation | 21590492; 23504318 |
| 12 | STAT3 | F2R | Activation | 23504318 |
| 13 | STAT3 | FGF2 | Activation | 21418908; 23086340 |
| 14 | STAT3 | FGF2 | Unknown | 16540670 |
| 15 | STAT3 | HIF1A | Activation | 17597020; 18644974; 19265129 |
| 16 | STAT3 | HIF1A | Unknown | 23991099 |
| 17 | STAT3 | IFNAR1 | Activation | 18550668 |
| 18 | STAT3 | IL2 | Activation | 18550668 |
| 19 | STAT3 | IL2RA | Unknown | 10068671; 11368440; 24159173 |
| 20 | STAT3 | IL6 | Activation | 10391682; 18765795; 20930550; 22547075; 22927445 |
| 21 | STAT3 | IL6 | Repression | 18616672 |
| 22 | STAT3 | IL6 | Unknown | 22105366; 22363173 |
| 23 | STAT3 | JAK2 | Activation | 17151100 |
| 24 | STAT3 | JAK2 | Unknown | 19783654 |
| 25 | STAT3 | MMP2 | Activation | 17533737; 19284568; 20069389 |
| 26 | STAT3 | MMP2 | Repression | 17533737 |
| 27 | STAT3 | MMP2 | Unknown | 16540670 |
| 28 | STAT3 | MMP7 | Activation | 18411043 |
| 29 | STAT3 | MMP7 | Repression | 20939893 |
| 30 | STAT3 | MMP9 | Repression | 20067773 |
| 31 | STAT3 | MUC1 | Activation | 17151127; 19578748; 21325207 |
| 32 | STAT3 | MUC4 | Activation | 18573283 |
| 33 | STAT3 | MUC4 | Unknown | 15485908 |
| 34 | STAT3 | MYC | Activation | 15184887; 17204573; 19259613 |
| 35 | STAT3 | MYC | Repression | 20067773; 22317895 |
| 36 | STAT3 | MYC | Unknown | 10464281; 15469392; 18184402; 20654581 |
| 37 | STAT3 | SHH | Activation | 22554932 |
| 38 | STAT3 | TWIST1 | Unknown | 17909010 |
| 39 | STAT3 | TWIST1 | Activation | 23623921 |
| 40 | STAT3 | TWIST1 | Unknown | 17909010 |
| 41 | STAT3 | VEGFA | Unknown | 23104276 |
| 42 | STAT3 | VEGFA | Activation | 11960372; 15735682; 17169602; 17533737; 19284568; 19880237; 21278793; 21418908 |
| 43 | STAT3 | VEGFA | Repression | 17533737; 19880237; 22313388 |
| 44 | STAT3 | VEGFA | Unknown | 12824281; 16540670; 16899623; 17937859; 18184402; 18320073; 19020709; 20043094; 21172343; 21344490; 21731766; 25101566 |