| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | ABCA1 | Unknown | 19783654 |
| 2 | STAT3 | AKT1 | Unknown | 16007214 |
| 3 | STAT3 | CCL2 | Activation | 24429361 |
| 4 | STAT3 | CHI3L1 | Activation | 21953450 |
| 5 | STAT3 | CRP | Activation | 12667216; 20978825; 23361365 |
| 6 | STAT3 | CRP | Unknown | 18292576 |
| 7 | STAT3 | ESR2 | Activation | 21546410 |
| 8 | STAT3 | ICAM1 | Unknown | 23690481; 8675499 |
| 9 | STAT3 | IL10 | Activation | 12817009; 18765795 |
| 10 | STAT3 | IL10 | Unknown | 10903771; 15034082; 17404037; 18403020; 19124156 |
| 11 | STAT3 | IL1RN | Activation | 20032313 |
| 12 | STAT3 | IL6 | Activation | 10391682; 18765795; 20930550; 22547075; 22927445 |
| 13 | STAT3 | IL6 | Repression | 18616672 |
| 14 | STAT3 | IL6 | Unknown | 22105366; 22363173 |
| 15 | STAT3 | JAK2 | Activation | 17151100 |
| 16 | STAT3 | JAK2 | Unknown | 19783654 |
| 17 | STAT3 | LCAT | Unknown | 12032172 |
| 18 | STAT3 | MMP1 | Unknown | 16205632; 17460772; 21410405 |
| 19 | STAT3 | MMP14 | Unknown | 14673954 |
| 20 | STAT3 | MMP2 | Activation | 17533737; 19284568; 20069389 |
| 21 | STAT3 | MMP2 | Repression | 17533737 |
| 22 | STAT3 | MMP2 | Unknown | 16540670 |
| 23 | STAT3 | MMP3 | Unknown | 17460772; 23967200 |
| 24 | STAT3 | MMP9 | Repression | 20067773 |
| 25 | STAT3 | NOX1 | Unknown | 19834108 |
| 26 | STAT3 | PTGS2 | Activation | 20145033 |
| 27 | STAT3 | PTGS2 | Unknown | 21172343 |
| 28 | STAT3 | TIMP1 | Activation | 15161657 |
| 29 | STAT3 | TIMP1 | Unknown | 11918744; 15920698 |
| 30 | STAT3 | UCP2 | Repression | 21344490 |
| 31 | STAT3 | VEGFA | Unknown | 23104276 |
| 32 | STAT3 | VEGFA | Activation | 11960372; 15735682; 17169602; 17533737; 19284568; 19880237; 21278793; 21418908 |
| 33 | STAT3 | VEGFA | Repression | 17533737; 19880237; 22313388 |
| 34 | STAT3 | VEGFA | Unknown | 12824281; 16540670; 16899623; 17937859; 18184402; 18320073; 19020709; 20043094; 21172343; 21344490; 21731766; 25101566 |