| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | AKT1 | Unknown | 16007214 |
| 2 | STAT3 | BCL2 | Activation | 15184887; 15805299; 18839277; 19926637; 21435102; 22504301 |
| 3 | STAT3 | BCL2 | Repression | 22313388 |
| 4 | STAT3 | BCL2 | Unknown | 18320073; 20043094; 20446017; 21172343; 21344490; 21385902 |
| 5 | STAT3 | CCL2 | Activation | 24429361 |
| 6 | STAT3 | HSPA4 | Activation | 19754877 |
| 7 | STAT3 | IL6 | Activation | 10391682; 18765795; 20930550; 22547075; 22927445 |
| 8 | STAT3 | IL6 | Repression | 18616672 |
| 9 | STAT3 | IL6 | Unknown | 22105366; 22363173 |
| 10 | STAT3 | IRF1 | Activation | 8647845 |
| 11 | STAT3 | IRF1 | Unknown | 10068671 |
| 12 | STAT3 | MMP9 | Repression | 20067773 |
| 13 | STAT3 | OSM | Activation | 10391682 |
| 14 | STAT3 | SOCS3 | Activation | 11788008; 15184887; 19332118; 20357037; 22179221 |
| 15 | STAT3 | SOCS3 | Unknown | 23335796 |