| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | AKT1 | Unknown | 16007214 |
| 2 | STAT3 | AR | Unknown | 23906537 |
| 3 | STAT3 | CDKN1A | Activation | 10023678; 15286705 |
| 4 | STAT3 | CDKN1A | Unknown | 16923815; 18320073; 20654581 |
| 5 | STAT3 | EGFR | Activation | 21590492; 23504318 |
| 6 | STAT3 | EPAS1 | Unknown | 23991099 |
| 7 | STAT3 | ESR2 | Activation | 21546410 |
| 8 | STAT3 | HIF1A | Activation | 17597020; 18644974; 19265129 |
| 9 | STAT3 | HIF1A | Unknown | 23991099 |
| 10 | STAT3 | MMP2 | Activation | 17533737; 19284568; 20069389 |
| 11 | STAT3 | MMP2 | Repression | 17533737 |
| 12 | STAT3 | MMP2 | Unknown | 16540670 |
| 13 | STAT3 | TIMP1 | Activation | 15161657 |
| 14 | STAT3 | TIMP1 | Unknown | 11918744; 15920698 |