| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | AKT1 | Unknown | 16007214 |
| 2 | STAT3 | BCL2L1 | Activation | 11369651; 15184887; 15805299; 16651438; 17880940; 20069389; 21435102 |
| 3 | STAT3 | BCL2L1 | Repression | 20067773 |
| 4 | STAT3 | BCL2L1 | Unknown | 15469392; 16384639; 18222423; 18790750; 20654581; 21172343; 21344490 |
| 5 | STAT3 | CDKN1B | Unknown | 18320073 |
| 6 | STAT3 | EGFR | Activation | 21590492; 23504318 |
| 7 | STAT3 | EPAS1 | Unknown | 23991099 |
| 8 | STAT3 | GFAP | Activation | 21833841 |
| 9 | STAT3 | GFAP | Unknown | 11740937 |
| 10 | STAT3 | ICAM1 | Unknown | 23690481; 8675499 |
| 11 | STAT3 | IL6 | Activation | 10391682; 18765795; 20930550; 22547075; 22927445 |
| 12 | STAT3 | IL6 | Repression | 18616672 |
| 13 | STAT3 | IL6 | Unknown | 22105366; 22363173 |
| 14 | STAT3 | MMP1 | Unknown | 16205632; 17460772; 21410405 |
| 15 | STAT3 | MMP3 | Unknown | 17460772; 23967200 |
| 16 | STAT3 | MMP7 | Activation | 18411043 |
| 17 | STAT3 | MMP7 | Repression | 20939893 |
| 18 | STAT3 | MMP9 | Repression | 20067773 |
| 19 | STAT3 | PTGS2 | Activation | 20145033 |
| 20 | STAT3 | PTGS2 | Unknown | 21172343 |
| 21 | STAT3 | STS | Activation | 21331591 |