| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | AKT1 | Unknown | 16007214 |
| 2 | STAT3 | CCND1 | Activation | 16651438; 19880237; 19926637; 21435102; 22218594 |
| 3 | STAT3 | CCND1 | Repression | 19880237; 22313388 |
| 4 | STAT3 | CCND1 | Unknown | 12147685; 15469392; 16384639; 16510571; 18184402; 20332458; 21172343; 21344490 |
| 5 | STAT3 | CCND2 | Unknown | 12147685 |
| 6 | STAT3 | CCND3 | Activation | 15184887 |
| 7 | STAT3 | CD46 | Activation | 17699108 |
| 8 | STAT3 | CDK4 | Activation | 22218594 |
| 9 | STAT3 | CDKN1B | Unknown | 18320073 |
| 10 | STAT3 | FAS | Activation | 15223310 |
| 11 | STAT3 | FAS | Repression | 16651438; 22313388 |
| 12 | STAT3 | IFNAR1 | Activation | 18550668 |
| 13 | STAT3 | IFNG | Repression | 18616672 |
| 14 | STAT3 | IKBKE | Activation | 22330135 |
| 15 | STAT3 | IL2 | Activation | 18550668 |
| 16 | STAT3 | IL2RA | Unknown | 10068671; 11368440; 24159173 |
| 17 | STAT3 | IL6 | Activation | 10391682; 18765795; 20930550; 22547075; 22927445 |
| 18 | STAT3 | IL6 | Repression | 18616672 |
| 19 | STAT3 | IL6 | Unknown | 22105366; 22363173 |
| 20 | STAT3 | JAK2 | Activation | 17151100 |
| 21 | STAT3 | JAK2 | Unknown | 19783654 |
| 22 | STAT3 | MYD88 | Unknown | 12244150 |
| 23 | STAT3 | OAS1 | Repression | 18550668 |
| 24 | STAT3 | STAT1 | Activation | 22693070 |
| 25 | STAT3 | TNFRSF10B | Repression | 19351839 |
| 26 | STAT3 | TP53 | Unknown | 20043094 |
| 27 | STAT3 | TYK2 | Repression | 18550668 |