| # | TF | Target | Mode of Regulation | References (PMID) |
|---|
| 1 | STAT3 | AKT1 | Unknown | 16007214 |
| 2 | STAT3 | BCL2 | Activation | 15184887; 15805299; 18839277; 19926637; 21435102; 22504301 |
| 3 | STAT3 | BCL2 | Repression | 22313388 |
| 4 | STAT3 | BCL2 | Unknown | 18320073; 20043094; 20446017; 21172343; 21344490; 21385902 |
| 5 | STAT3 | BIRC5 | Activation | 15184887; 16651438; 17880940; 19284568; 19880237 |
| 6 | STAT3 | BIRC5 | Unknown | 15469392; 20826784; 21344490 |
| 7 | STAT3 | CDKN1B | Unknown | 18320073 |
| 8 | STAT3 | CFLAR | Unknown | 18222423 |
| 9 | STAT3 | FAS | Activation | 15223310 |
| 10 | STAT3 | FAS | Repression | 16651438; 22313388 |
| 11 | STAT3 | FGF2 | Activation | 21418908; 23086340 |
| 12 | STAT3 | FGF2 | Unknown | 16540670 |
| 13 | STAT3 | ICAM1 | Unknown | 23690481; 8675499 |
| 14 | STAT3 | IL10 | Activation | 12817009; 18765795 |
| 15 | STAT3 | IL10 | Unknown | 10903771; 15034082; 17404037; 18403020; 19124156 |
| 16 | STAT3 | IL1RN | Activation | 20032313 |
| 17 | STAT3 | JAK2 | Activation | 17151100 |
| 18 | STAT3 | JAK2 | Unknown | 19783654 |
| 19 | STAT3 | JUNB | Activation | 17204573 |
| 20 | STAT3 | MMP2 | Activation | 17533737; 19284568; 20069389 |
| 21 | STAT3 | MMP2 | Repression | 17533737 |
| 22 | STAT3 | MMP2 | Unknown | 16540670 |
| 23 | STAT3 | MMP9 | Repression | 20067773 |
| 24 | STAT3 | PTGS2 | Activation | 20145033 |
| 25 | STAT3 | PTGS2 | Unknown | 21172343 |
| 26 | STAT3 | TIMP1 | Activation | 15161657 |
| 27 | STAT3 | TIMP1 | Unknown | 11918744; 15920698 |