STAT3 is a Transcription Factor.

1. Targets and Regulators

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STAT3 targets

#	TF	Target	Mode of Regulation	References (PMID)
1	STAT3	A2M	Unknown	11466367
2	STAT3	ABCA1	Unknown	19783654
3	STAT3	AKAP12	Activation	22584896
4	STAT3	AKT1	Unknown	16007214
5	STAT3	AR	Unknown	23906537
6	STAT3	BCL2	Activation	15184887; 15805299; 18839277; 19926637; 21435102; 22504301
7	STAT3	BCL2	Repression	22313388
8	STAT3	BCL2	Unknown	18320073; 20043094; 20446017; 21172343; 21344490; 21385902
9	STAT3	BCL2L1	Activation	11369651; 15184887; 15805299; 16651438; 17880940; 20069389; 21435102
10	STAT3	BCL2L1	Repression	20067773
11	STAT3	BCL2L1	Unknown	15469392; 16384639; 18222423; 18790750; 20654581; 21172343; 21344490
12	STAT3	BCL6	Activation	20228272; 23716595
13	STAT3	BIRC5	Activation	15184887; 16651438; 17880940; 19284568; 19880237
14	STAT3	BIRC5	Unknown	15469392; 20826784; 21344490
15	STAT3	CCL11	Activation	19265112
16	STAT3	CCL11	Unknown	20169197
17	STAT3	CCL2	Activation	24429361
18	STAT3	CCND1	Activation	16651438; 19880237; 19926637; 21435102; 22218594
19	STAT3	CCND1	Repression	19880237; 22313388
20	STAT3	CCND1	Unknown	12147685; 15469392; 16384639; 16510571; 18184402; 20332458; 21172343; 21344490
21	STAT3	CCND2	Unknown	12147685
22	STAT3	CCND3	Activation	15184887
23	STAT3	CD46	Activation	17699108
24	STAT3	CDH1	Unknown	18320073; 22205702
25	STAT3	CDK4	Activation	22218594
26	STAT3	CDKN1A	Activation	10023678; 15286705
27	STAT3	CDKN1A	Unknown	16923815; 18320073; 20654581
28	STAT3	CDKN1B	Unknown	18320073
29	STAT3	CFB	Activation	22169226
30	STAT3	CFLAR	Unknown	18222423
31	STAT3	CHI3L1	Activation	21953450
32	STAT3	CISH	Activation	14630083
33	STAT3	COPS5	Unknown	21689417
34	STAT3	CRP	Activation	12667216; 20978825; 23361365
35	STAT3	CRP	Unknown	18292576
36	STAT3	CSRP1	Activation	8621622
37	STAT3	CSRP1	Unknown	18292576
38	STAT3	CTGF	Repression	21245987
39	STAT3	CXCL8	Unknown	17726017
40	STAT3	CYP19A1	Unknown	15072557
41	STAT3	CYR61	Unknown	22401280
42	STAT3	DDIT3	Repression	23288901
43	STAT3	DIRAS3	Unknown	23604529
44	STAT3	DNMT1	Activation	16861352; 21944426
45	STAT3	DNMT1	Unknown	19887607; 23604529
46	STAT3	EGFR	Activation	21590492; 23504318
47	STAT3	EPAS1	Unknown	23991099
48	STAT3	ESR2	Activation	21546410
49	STAT3	ETV6	Activation	15229229
50	STAT3	F2R	Activation	23504318
51	STAT3	FAAH	Activation	12556536
52	STAT3	FAS	Activation	15223310
53	STAT3	FAS	Repression	16651438; 22313388
54	STAT3	FGF1	Repression	14673954
55	STAT3	FGF2	Activation	21418908; 23086340
56	STAT3	FGF2	Unknown	16540670
57	STAT3	FGG	Activation	11460505
58	STAT3	FGL1	Unknown	19304666
59	STAT3	FLT3	Activation	16418395
60	STAT3	FOS	Activation	12600988; 14737107; 17204573
61	STAT3	GAST	Activation	20568281
62	STAT3	GAST	Unknown	20949125
63	STAT3	GFAP	Activation	21833841
64	STAT3	GFAP	Unknown	11740937
65	STAT3	GREB1	Unknown	23056300
66	STAT3	HAMP	Activation	18671304
67	STAT3	HAMP	Unknown	16835372
68	STAT3	HGF	Activation	12168776
69	STAT3	HGF	Unknown	23954444
70	STAT3	HIF1A	Activation	17597020; 18644974; 19265129
71	STAT3	HIF1A	Unknown	23991099
72	STAT3	HMOX1	Activation	19129475
73	STAT3	HP	Unknown	17645497
74	STAT3	HSPA4	Activation	19754877
75	STAT3	HSPB1	Activation	14715258
76	STAT3	ICAM1	Unknown	23690481; 8675499
77	STAT3	IFNAR1	Activation	18550668
78	STAT3	IFNG	Repression	18616672
79	STAT3	IKBKE	Activation	22330135
80	STAT3	IL10	Activation	12817009; 18765795
81	STAT3	IL10	Unknown	10903771; 15034082; 17404037; 18403020; 19124156
82	STAT3	IL11	Unknown	23224145
83	STAT3	IL1RN	Activation	20032313
84	STAT3	IL2	Activation	18550668
85	STAT3	IL21	Activation	18209077
86	STAT3	IL2RA	Unknown	10068671; 11368440; 24159173
87	STAT3	IL6	Activation	10391682; 18765795; 20930550; 22547075; 22927445
88	STAT3	IL6	Repression	18616672
89	STAT3	IL6	Unknown	22105366; 22363173
90	STAT3	IRF1	Activation	8647845
91	STAT3	IRF1	Unknown	10068671
92	STAT3	JAK2	Activation	17151100
93	STAT3	JAK2	Unknown	19783654
94	STAT3	JUNB	Activation	17204573
95	STAT3	KLF11	Activation	18505768
96	STAT3	KRT17	Activation	21796151
97	STAT3	LCAT	Unknown	12032172
98	STAT3	LEP	Activation	18242580; 19492417
99	STAT3	LGALS3BP	Repression	18594176
100	STAT3	LTBP1	Repression	22814105
101	STAT3	MCL1	Activation	15184887; 15805299; 16432172; 17880940; 19523441
102	STAT3	MCL1	Repression	22313388
103	STAT3	MCL1	Unknown	15469392; 16317687; 18790750; 19595668; 20654581; 22465052
104	STAT3	MDC1	Unknown	20804538
105	STAT3	MICA	Repression	21257710; 23686482
106	STAT3	MMP1	Unknown	16205632; 17460772; 21410405
107	STAT3	MMP10	Unknown	16205632
108	STAT3	MMP14	Unknown	14673954
109	STAT3	MMP2	Activation	17533737; 19284568; 20069389
110	STAT3	MMP2	Repression	17533737
111	STAT3	MMP2	Unknown	16540670
112	STAT3	MMP3	Unknown	17460772; 23967200
113	STAT3	MMP7	Activation	18411043
114	STAT3	MMP7	Repression	20939893
115	STAT3	MMP9	Repression	20067773
116	STAT3	MUC1	Activation	17151127; 19578748; 21325207
117	STAT3	MUC4	Activation	18573283
118	STAT3	MUC4	Unknown	15485908
119	STAT3	MUC5B	Unknown	15485908
120	STAT3	MYC	Activation	15184887; 17204573; 19259613
121	STAT3	MYC	Repression	20067773; 22317895
122	STAT3	MYC	Unknown	10464281; 15469392; 18184402; 20654581
123	STAT3	MYD88	Unknown	12244150
124	STAT3	NANOG	Activation	21689689
125	STAT3	NLK	Unknown	15764709
126	STAT3	NME1	Activation	23583378
127	STAT3	NOX1	Unknown	19834108
128	STAT3	NOX4	Unknown	19834108
129	STAT3	NOX5	Activation	22348975
130	STAT3	NR2C2	Unknown	15764709
131	STAT3	OAS1	Repression	18550668
132	STAT3	OPRM1	Activation	15448191
133	STAT3	OSM	Activation	10391682
134	STAT3	PAX3	Repression	19074888
135	STAT3	PGF	Repression	23042533
136	STAT3	PHB	Unknown	17324931
137	STAT3	PIAS3	Activation	14630083
138	STAT3	PIM1	Activation	22273698
139	STAT3	PIM1	Unknown	10068671
140	STAT3	POU2F1	Unknown	23172665
141	STAT3	PPARA	Activation	24242046
142	STAT3	PRDM1	Activation	1702555
143	STAT3	PRDM1	Unknown	12953803
144	STAT3	PROS1	Unknown	16840717
145	STAT3	PSMB5	Activation	24627483
146	STAT3	PTEN	Activation	22055460
147	STAT3	PTGS2	Activation	20145033
148	STAT3	PTGS2	Unknown	21172343
149	STAT3	PTPN13	Activation	24191246
150	STAT3	PTPN6	Repression	14630083; 16825495; 21792937
151	STAT3	PTPN6	Unknown	15870198
152	STAT3	ROR1	Unknown	20686606
153	STAT3	S100A11	Activation	24376686
154	STAT3	S1PR1	Activation	21102457
155	STAT3	SAA1	Unknown	16236134; 23391827
156	STAT3	SALL4	Activation	19151334
157	STAT3	SHH	Activation	22554932
158	STAT3	SOCS1	Activation	14630083; 20003295; 20357037
159	STAT3	SOCS3	Activation	11788008; 15184887; 19332118; 20357037; 22179221
160	STAT3	SOCS3	Unknown	23335796
161	STAT3	STAT1	Activation	22693070
162	STAT3	STK11	Unknown	24913037
163	STAT3	STS	Activation	21331591
164	STAT3	TERT	Activation	20171193; 23158658
165	STAT3	TGFB1	Activation	16474852
166	STAT3	TIMP1	Activation	15161657
167	STAT3	TIMP1	Unknown	11918744; 15920698
168	STAT3	TNFRSF10B	Repression	19351839
169	STAT3	TP53	Unknown	20043094
170	STAT3	TP63	Activation	18198175
171	STAT3	TRH	Unknown	11134186
172	STAT3	TWIST1	Unknown	17909010
173	STAT3	TWIST1	Activation	23623921
174	STAT3	TWIST1	Unknown	17909010
175	STAT3	TWIST2	Unknown	17909010
176	STAT3	TYK2	Repression	18550668
177	STAT3	UCP2	Repression	21344490
178	STAT3	USP7	Repression	22750444
179	STAT3	VDR	Repression	23424038
180	STAT3	VEGFA	Unknown	23104276
181	STAT3	VEGFA	Activation	11960372; 15735682; 17169602; 17533737; 19284568; 19880237; 21278793; 21418908
182	STAT3	VEGFA	Repression	17533737; 19880237; 22313388
183	STAT3	VEGFA	Unknown	12824281; 16540670; 16899623; 17937859; 18184402; 18320073; 19020709; 20043094; 21172343; 21344490; 21731766; 25101566
184	STAT3	VEGFB	Unknown	16899623; 21731766
185	STAT3	ZFP36	Activation	21606497

Modularity measured by P value : 0.001

TFs that regulate STAT3

#	TF	Target	Mode of Regulation	References (PMID)
1	BCL6	STAT3	Unknown	17951530
2	BRCA1	STAT3	Unknown	11163768
3	CEBPA	STAT3	Unknown	24429361
4	HDAC1	STAT3	Unknown	18611949
5	HIC1	STAT3	Activation	24067369
6	HIF1A	STAT3	Unknown	23991099
7	KAT5	STAT3	Repression	12551922
8	PIAS3	STAT3	Unknown	16098628
9	RELA	STAT3	Unknown	25040843
10	SPI1	STAT3	Unknown	24429361
11	STAT1	STAT3	Unknown	22693070
12	TCF7L2	STAT3	Unknown	18602747
13	TP53	STAT3	Repression	11809683
14	ZNF382	STAT3	Repression	20682794

2. Other TFs that share targets with STAT3

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TFs that share targets with STAT3

*P values are calculated with hypergeometric test.

TF	# of overlapped target genes	P value	FDR
RELA	59	7.02e-66	5.11e-63
NFKB1	59	8.60e-66	5.69e-63
STAT1	30	1.08e-40	3.74e-38
SP1	49	3.61e-40	1.14e-37
JUN	30	3.18e-33	5.65e-31
TP53	25	6.92e-25	5.93e-23
HDAC1	20	8.60e-25	7.27e-23
ESR1	18	7.95e-22	5.26e-20
HIF1A	18	6.98e-21	4.34e-19
EGR1	18	2.09e-20	1.24e-18
PPARG	16	1.87e-19	1.05e-17
TFAP2A	16	3.08e-19	1.70e-17
BRCA1	15	5.69e-19	3.02e-17
CEBPB	15	2.20e-18	1.08e-16
SIRT1	14	8.66e-18	3.84e-16
FOS	14	1.51e-17	6.50e-16
STAT4	9	2.43e-17	1.02e-15
WT1	13	6.46e-16	2.36e-14
SP3	16	1.42e-15	4.96e-14
ETV4	10	1.52e-15	5.28e-14
KLF4	11	8.89e-15	2.81e-13
HDAC2	10	9.91e-15	3.12e-13
REL	9	5.13e-14	1.40e-12
EP300	12	1.10e-13	2.83e-12
ETS2	10	1.32e-13	3.35e-12
MYC	14	2.20e-13	5.36e-12
CREB1	13	4.01e-13	9.29e-12
E2F1	15	4.98e-13	1.13e-11
CEBPA	11	5.69e-13	1.28e-11
PGR	9	6.83e-13	1.52e-11
AR	13	1.81e-12	3.66e-11
SMAD3	9	2.70e-12	5.18e-11
PAX5	8	2.75e-12	5.26e-11
USF2	10	5.37e-12	9.87e-11
STAT5A	7	6.28e-12	1.14e-10
TWIST1	9	8.81e-12	1.55e-10
ATM	8	9.73e-12	1.69e-10
ETS1	12	1.15e-11	1.97e-10
ING4	7	1.17e-11	2.00e-10
ATF4	9	1.51e-11	2.52e-10
STAT6	9	2.49e-11	3.98e-10
EZH2	9	3.17e-11	4.94e-10
ZNF300	5	3.18e-11	4.94e-10
ABL1	6	5.07e-11	7.61e-10
HOXB7	6	5.07e-11	7.61e-10
VDR	9	1.76e-10	2.34e-09
JUND	8	2.24e-10	2.86e-09
YY1	11	3.16e-10	3.92e-09
CTNNB1	7	4.22e-10	5.04e-09
NR3C1	8	5.88e-10	6.65e-09
MTA1	7	1.11e-09	1.15e-08
SMAD4	7	1.49e-09	1.50e-08
TCF4	7	1.49e-09	1.50e-08
STAT5B	5	1.75e-09	1.71e-08
TBP	6	1.86e-09	1.80e-08
PARP1	7	1.97e-09	1.89e-08
USF1	9	2.82e-09	2.62e-08
FOXO3	6	4.25e-09	3.71e-08
RB1	7	4.29e-09	3.74e-08
SRF	7	4.29e-09	3.74e-08
GLI1	6	6.17e-09	5.21e-08
NFKBIA	6	6.17e-09	5.21e-08
HIPK2	5	7.75e-09	6.36e-08
ZFP36	5	7.75e-09	6.36e-08
IRF1	8	8.23e-09	6.70e-08
VHL	6	8.75e-09	7.06e-08
NPM1	5	1.41e-08	1.08e-07
E2F4	6	3.87e-08	2.58e-07
APC	5	3.88e-08	2.59e-07
HDAC3	6	4.99e-08	3.22e-07
HDGF	4	6.00e-08	3.77e-07
IFI16	4	6.00e-08	3.77e-07
SOX6	4	6.00e-08	3.77e-07
BCL6	6	8.06e-08	4.88e-07
NFYB	5	8.94e-08	5.27e-07
CREBBP	6	1.25e-07	7.01e-07
RUNX3	6	1.25e-07	7.01e-07
HOXA1	4	1.39e-07	7.71e-07
DNMT1	6	1.54e-07	8.45e-07
PTTG1	5	1.82e-07	9.71e-07
ATF2	6	2.29e-07	1.20e-06
FOXM1	5	2.50e-07	1.29e-06
GLI2	5	2.50e-07	1.29e-06
ELK1	5	4.47e-07	2.13e-06
KLF5	5	4.47e-07	2.13e-06
PML	5	4.47e-07	2.13e-06
RUNX2	5	4.47e-07	2.13e-06
XBP1	5	4.47e-07	2.13e-06
SMARCA4	4	4.95e-07	2.32e-06
SNAI2	5	5.83e-07	2.67e-06
ATF3	5	7.49e-07	3.30e-06
HDAC9	5	7.49e-07	3.30e-06
NFYA	5	7.49e-07	3.30e-06
NKX3-1	4	8.19e-07	3.56e-06
SMAD7	4	8.19e-07	3.56e-06
GATA3	6	1.02e-06	4.29e-06
MSC	4	1.28e-06	5.15e-06
NFATC2	4	1.28e-06	5.15e-06
FLI1	5	1.48e-06	5.82e-06
TWIST2	5	1.48e-06	5.82e-06
FOXO1	5	1.82e-06	6.92e-06
NR1I2	5	1.82e-06	6.92e-06
FOXP3	4	1.91e-06	7.21e-06
ERG	5	2.69e-06	9.52e-06
HDAC7	4	2.74e-06	9.66e-06
STAT2	4	2.74e-06	9.66e-06
TP73	4	2.74e-06	9.66e-06
MYCN	6	2.94e-06	1.03e-05
NFYC	4	3.81e-06	1.27e-05
ZEB1	4	3.81e-06	1.27e-05
YBX1	5	4.56e-06	1.47e-05
FHL2	3	5.07e-06	1.61e-05
FUS	3	5.07e-06	1.61e-05
NUPR1	3	5.07e-06	1.61e-05
PIAS2	3	5.07e-06	1.61e-05
SATB1	4	5.16e-06	1.63e-05
CTCF	5	7.33e-06	2.18e-05
CEBPD	4	8.89e-06	2.55e-05
DDIT3	4	8.89e-06	2.55e-05
ELF4	3	1.01e-05	2.84e-05
FOXQ1	3	1.01e-05	2.84e-05
IKBKB	3	1.01e-05	2.84e-05
LEF1	5	1.13e-05	3.10e-05
HMGA1	4	1.14e-05	3.11e-05
POU2F1	5	1.29e-05	3.44e-05
AATF	3	1.75e-05	4.43e-05
HSF2	3	1.75e-05	4.43e-05
NFKB2	3	1.75e-05	4.43e-05
TFAP4	3	1.75e-05	4.43e-05
ESR2	4	1.78e-05	4.48e-05
KLF6	4	1.78e-05	4.48e-05
ERCC2	3	2.79e-05	6.45e-05
IRF9	3	2.79e-05	6.45e-05
MAZ	3	2.79e-05	6.45e-05
PIAS1	3	2.79e-05	6.45e-05
SALL4	3	2.79e-05	6.45e-05
AHR	4	3.18e-05	7.18e-05
HDAC4	4	3.80e-05	8.34e-05
KLF8	3	4.16e-05	8.86e-05
NCOA3	3	4.16e-05	8.86e-05
NFATC1	3	4.16e-05	8.86e-05
SOX9	4	4.49e-05	9.42e-05
PROX1	3	5.90e-05	1.17e-04
SREBF1	4	6.15e-05	1.21e-04
MEN1	3	8.07e-05	1.53e-04
CREB5	3	1.07e-04	1.92e-04
GATA1	5	1.12e-04	2.00e-04
NF1	3	1.75e-04	2.88e-04
E2F3	3	2.17e-04	3.45e-04
FOSL2	3	2.17e-04	3.45e-04
JUNB	3	2.17e-04	3.45e-04
TCF3	3	2.17e-04	3.45e-04
TP63	3	2.17e-04	3.45e-04
RUNX1	4	3.25e-04	4.85e-04
FOXA2	3	3.83e-04	5.53e-04
HNF4A	4	5.08e-04	7.00e-04
NR1H4	3	5.29e-04	7.26e-04
PPARA	4	5.52e-04	7.51e-04
DEK	2	6.35e-04	8.42e-04
HDAC11	2	6.35e-04	8.42e-04
HOXA7	2	6.35e-04	8.42e-04
KDM4B	2	6.35e-04	8.42e-04
MED1	2	6.35e-04	8.42e-04
NR4A2	2	6.35e-04	8.42e-04
TAF1	2	6.35e-04	8.42e-04
TSC22D3	2	6.35e-04	8.42e-04
ZNF24	2	6.35e-04	8.42e-04
ARNT	3	7.06e-04	9.23e-04
FOXA1	3	7.06e-04	9.23e-04
ATF1	3	9.17e-04	1.15e-03
FOXL2	2	9.47e-04	1.18e-03
FOXO4	2	9.47e-04	1.18e-03
MAX	2	9.47e-04	1.18e-03
MYOD1	2	9.47e-04	1.18e-03
MYOG	2	9.47e-04	1.18e-03
MZF1	2	9.47e-04	1.18e-03
PAX3	2	9.47e-04	1.18e-03
RARG	2	9.47e-04	1.18e-03
RBL1	2	9.47e-04	1.18e-03
SMAD2	2	9.47e-04	1.18e-03
POU5F1	3	1.16e-03	1.41e-03
NFIC	3	1.30e-03	1.57e-03
ILF3	2	1.32e-03	1.58e-03
KLF10	2	1.32e-03	1.58e-03
HNF1A	3	1.45e-03	1.72e-03
ATF5	2	1.75e-03	2.04e-03
CEBPE	2	1.75e-03	2.04e-03
ING1	2	1.75e-03	2.04e-03
MYBL2	2	1.75e-03	2.04e-03
RBMX	2	1.75e-03	2.04e-03
ZBTB7A	2	1.75e-03	2.04e-03
CIITA	3	2.14e-03	2.45e-03
ELF3	2	2.24e-03	2.55e-03
SP4	2	2.24e-03	2.55e-03
ZNF148	2	2.24e-03	2.55e-03
CDX2	3	2.34e-03	2.66e-03
HSF1	3	2.34e-03	2.66e-03
REST	3	2.56e-03	2.87e-03
EGR2	2	2.78e-03	3.09e-03
EPAS1	2	2.78e-03	3.09e-03
EWSR1	2	2.78e-03	3.09e-03
LMO2	2	2.78e-03	3.09e-03
NFIL3	2	2.78e-03	3.09e-03
SNAI1	2	2.78e-03	3.09e-03
TFAP2C	2	2.78e-03	3.09e-03
ZNF382	2	2.78e-03	3.09e-03
HIC1	2	3.38e-03	3.69e-03
IRF4	2	3.38e-03	3.69e-03
KLF2	2	3.38e-03	3.69e-03
SPDEF	2	3.38e-03	3.69e-03
MYB	3	3.79e-03	4.11e-03
TCF7L2	2	4.04e-03	4.35e-03
IRF8	2	4.75e-03	5.06e-03
KAT2B	2	5.51e-03	5.83e-03
SP100	2	5.51e-03	5.83e-03
HOXA10	2	6.32e-03	6.65e-03
NR4A1	2	6.32e-03	6.65e-03
TBX21	2	6.32e-03	6.65e-03
RFX1	2	7.19e-03	7.50e-03
NFE2L2	2	8.10e-03	8.40e-03
RXRA	2	1.11e-02	1.14e-02
SREBF2	2	1.11e-02	1.14e-02
NR5A1	2	1.34e-02	1.37e-02
GATA4	2	1.58e-02	1.61e-02
SOX2	2	1.71e-02	1.74e-02
CREM	2	1.85e-02	1.87e-02
RARA	2	1.98e-02	2.01e-02
MITF	2	2.13e-02	2.15e-02

3. Diseases / Pathways associated with STAT3

top

- Disease Ontology terms

#	Description	Term ID	# of overlapped genes	P value	FDR

1	cancer	DOID:162	62	1.471e-45	7.970e-43
2	Malignant neoplasm of prostate	DOID:10283	50	2.469e-42	1.031e-39
3	Malignant neoplasm of breast	DOID:4241	54	5.693e-42	2.338e-39
4	disease	DOID:4	90	1.705e-41	6.782e-39
5	Primary carcinoma of the liver cells	DOID:684	41	1.430e-39	4.551e-37
6	Squamous cell carcinoma	DOID:1749	36	1.206e-37	3.656e-35
7	Malignant neoplasm of stomach	DOID:10534	37	2.767e-37	8.139e-35
8	Neoplasm Metastasis	DOID:2619	41	3.189e-37	9.228e-35
9	Malignant Neoplasms	DOID:462	54	1.700e-36	4.606e-34
10	Rheumatoid Arthritis	DOID:7148	37	7.168e-35	1.772e-32
11	Endometriosis	DOID:289	29	1.104e-33	2.488e-31
12	Melanoma	DOID:1909	35	8.366e-33	1.790e-30
13	Renal Cell Carcinoma	DOID:4450	29	7.864e-32	1.602e-29
14	Multiple Myeloma	DOID:9538	26	2.915e-30	5.302e-28
15	Embryoma	DOID:4766	42	3.350e-30	5.966e-28
16	Malignant neoplasm of ovary	DOID:2144	29	5.993e-29	9.193e-27
17	Carcinoma of the Large Intestine	DOID:1994	32	8.187e-28	1.115e-25
18	Infection	DOID:945	30	1.123e-27	1.512e-25
19	Endometrial Carcinoma	DOID:2871	23	1.389e-26	1.637e-24
20	Malignant tumor of colon	DOID:219	27	8.611e-25	8.565e-23
21	Malignant neoplasm of cervix uteri	DOID:4361	21	1.603e-24	1.540e-22
22	Lymphoma	DOID:353	21	1.603e-24	1.540e-22
23	Atherosclerosis	DOID:1936	22	6.312e-24	5.761e-22
24	Leukemia	DOID:1240	27	6.793e-24	6.156e-22
25	Malignant neoplasm of pancreas	DOID:1793	25	1.194e-23	1.060e-21
26	Degenerative polyarthritis	DOID:455	19	5.631e-23	4.732e-21
27	Metastasis to Lymph Nodes	DOID:10437	20	6.112e-23	5.103e-21
28	Carcinoma	DOID:305	23	6.110e-23	5.103e-21
29	Adenocarcinoma	DOID:299	23	1.883e-22	1.480e-20
30	Obesity	DOID:9970	23	7.096e-22	5.299e-20
31	Stomach Carcinoma	DOID:5517	19	1.791e-21	1.300e-19
32	Glioma	DOID:2627	23	2.188e-21	1.565e-19
33	Multiple Sclerosis	DOID:2377	20	2.540e-21	1.807e-19
34	Diabetes Mellitus, Non-Insulin-Dependent	DOID:9352	27	3.261e-21	2.275e-19
35	Malignant neoplasm of lung	DOID:1324	25	5.980e-21	4.061e-19
36	Dental Plaque	DOID:13598	16	6.415e-21	4.344e-19
37	Cervical Squamous Cell Carcinoma	DOID:3744	17	2.415e-20	1.518e-18
38	Malignant Glioma	DOID:3070	21	3.610e-20	2.220e-18
39	Hodgkin's disease, unspecified type	DOID:8567	16	3.115e-19	1.740e-17
40	Malignant neoplasm of endometrium	DOID:5654	15	7.291e-19	3.942e-17
41	Systemic infection	DOID:2288	15	1.203e-17	5.570e-16
42	Uterine Fibroids	DOID:13223	12	2.094e-17	9.340e-16
43	Astrocytoma	DOID:3069	14	2.515e-17	1.117e-15
44	Primary Tumor	DOID:8176	15	3.341e-17	1.467e-15
45	Carcinoma of lung	DOID:3905	12	6.420e-17	2.707e-15
46	Asthma	DOID:2841	18	6.511e-17	2.729e-15
47	Glioblastoma	DOID:3068	16	7.496e-17	3.104e-15
48	Carcinoma of Nasopharynx	DOID:9261	13	1.146e-16	4.633e-15
49	Malignant neoplasm of urinary bladder	DOID:11054	15	5.736e-16	2.098e-14
50	Coronary Arteriosclerosis	DOID:3363	17	5.807e-16	2.115e-14
51	Osteosarcoma	DOID:3347	14	9.103e-16	3.202e-14
52	Myeloid leukemia, acute	DOID:9119	18	1.561e-15	5.387e-14
53	Breast Carcinoma	DOID:3459	16	1.701e-15	5.822e-14
54	Pre-Eclampsia	DOID:10591	15	4.013e-15	1.302e-13
55	Myeloid leukemia, chronic	DOID:8552	11	1.747e-14	5.189e-13
56	Infiltrating Malignant Neoplasm	DOID:8062	11	2.297e-14	6.686e-13
57	Hypertension induced by pregnancy	DOID:12684	15	2.491e-14	7.207e-13
58	Esophageal carcinoma	DOID:1107	9	2.621e-14	7.507e-13
59	Small cell carcinoma of lung	DOID:5409	13	3.860e-14	1.073e-12
60	Congenital Abnormality	DOID:759	18	3.923e-14	1.088e-12
61	Adenocarcinoma of Esophagus	DOID:4914	10	4.530e-14	1.244e-12
62	Malignant neoplasm of esophagus	DOID:1104	13	4.548e-14	1.248e-12
63	Leukemia, Lymphocytic, chronic	DOID:1040	14	4.723e-14	1.295e-12
64	Polycystic Ovary syndrome	DOID:11612	12	5.601e-14	1.514e-12
65	Prostate carcinoma	DOID:10286	12	5.601e-14	1.514e-12
66	Rheumatism	DOID:4256	10	6.301e-14	1.693e-12
67	Carcinoma, Transitional Cell	DOID:3995	11	6.428e-14	1.718e-12
68	acute leukemia	DOID:12603	11	8.189e-14	2.132e-12
69	Malignant neoplasm of mouth, unspecified	DOID:8894	11	8.189e-14	2.132e-12
70	Liver neoplasms	DOID:3571	12	9.935e-14	2.552e-12
71	Systemic Scleroderma	DOID:418	13	1.163e-13	2.948e-12
72	Epithelial ovarian cancer	DOID:4001	10	2.127e-13	5.139e-12
73	Osteosarcoma of Bone	DOID:3376	12	2.430e-13	5.837e-12
74	Neuroblastoma	DOID:769	14	2.473e-13	5.918e-12
75	Hypertension	DOID:10763	15	2.600e-13	6.148e-12
76	Colonic Neoplasms	DOID:235	9	3.503e-13	8.022e-12
77	Adenovirus Infections	DOID:3124	11	3.868e-13	8.787e-12
78	chronic Obstructive Airway disease	DOID:3083	12	5.559e-13	1.230e-11
79	Ankylosing spondylitis	DOID:7147	8	5.697e-13	1.257e-11
80	Cholangiocarcinoma	DOID:4947	10	6.254e-13	1.362e-11
81	Arthritis	DOID:848	10	6.254e-13	1.362e-11
82	Systemic lupus erythematosus	DOID:9074	14	6.931e-13	1.496e-11
83	Neoplasm, Ovarian	DOID:2394	11	1.243e-12	2.539e-11
84	HIV Infections	DOID:526	13	1.336e-12	2.709e-11
85	Cerebrovascular accident	DOID:3455	12	1.610e-12	3.211e-11
86	Adenoma	DOID:657	12	1.860e-12	3.665e-11
87	Esophageal Neoplasms	DOID:5041	12	2.466e-12	4.756e-11
88	Tuberculosis	DOID:399	11	2.528e-12	4.861e-11
89	Celiac disease	DOID:10608	9	2.561e-12	4.918e-11
90	Ulcerative colitis, unspecified	DOID:8577	12	4.247e-12	7.854e-11
91	Alzheimer's disease	DOID:10652	16	5.411e-12	9.745e-11
92	Fibroid Tumor	DOID:127	9	5.959e-12	1.066e-10
93	Lymphatic Metastasis	DOID:4100	7	6.934e-12	1.226e-10
94	Hamman-Rich syndrome	DOID:2797	9	1.002e-11	1.702e-10
95	Ischemia	DOID:326	10	1.069e-11	1.807e-10
96	Bacterial Infections	DOID:104	7	1.225e-11	2.035e-10
97	Cervix carcinoma	DOID:2893	9	1.285e-11	2.125e-10
98	Neoplasms, Epithelial	DOID:157	8	1.591e-11	2.580e-10
99	Thyroid carcinoma	DOID:3963	9	1.636e-11	2.644e-10
100	Periodontitis	DOID:824	9	2.069e-11	3.279e-10
101	Regional enteritis of unspecified site	DOID:8778	11	2.181e-11	3.439e-10
102	Colon Carcinoma	DOID:1520	10	5.944e-11	8.509e-10
103	Proliferative diabetic retinopathy	DOID:13207	6	7.067e-11	9.948e-10
104	Germ cell tumor	DOID:2994	7	8.096e-11	1.124e-09
105	Unspecified myeloid leukemia	DOID:8692	9	9.120e-11	1.253e-09
106	Anemia	DOID:2355	7	1.207e-10	1.611e-09
107	Meningioma	DOID:3565	9	1.333e-10	1.764e-09
108	Malignant Squamous Cell Neoplasm	DOID:5512	6	1.405e-10	1.848e-09
109	Diabetes Mellitus	DOID:9351	11	2.517e-10	3.140e-09
110	Temporal Arteritis	DOID:13375	6	2.593e-10	3.216e-09
111	Stomach Neoplasms	DOID:4713	8	2.597e-10	3.220e-09
112	malaria	DOID:12365	8	3.269e-10	3.953e-09
113	Aortic Aneurysm, Abdominal	DOID:7693	7	3.525e-10	4.230e-09
114	Nodular lymphoma	DOID:8524	7	6.617e-10	7.472e-09
115	Prostatic Hypertrophy, Benign	DOID:11131	8	1.141e-09	1.225e-08
116	Hepatitis C, chronic	DOID:2049	8	1.141e-09	1.225e-08
117	Testicular dysfunction	DOID:11019	8	1.141e-09	1.225e-08
118	Advanced Cancer	DOID:2337	8	1.141e-09	1.225e-08
119	Breast Cancer Stage IV	DOID:6267	8	1.141e-09	1.225e-08
120	Carcinoma in situ	DOID:8719	6	1.188e-09	1.267e-08
121	Lichen planus	DOID:9201	5	1.200e-09	1.279e-08
122	autoimmune disease	DOID:417	9	1.282e-09	1.356e-08
123	Pituitary Adenoma	DOID:3829	7	1.541e-09	1.596e-08
124	Diabetic Retinopathy	DOID:8947	8	1.659e-09	1.704e-08
125	Behcet syndrome	DOID:13241	8	1.986e-09	2.004e-08
126	HTLV-I Infections	DOID:323	5	2.684e-09	2.621e-08
127	Subacute sclerosing panencephalitis	DOID:8970	5	2.684e-09	2.621e-08
128	schizophrenia	DOID:5419	13	3.825e-09	3.590e-08
129	Adenocarcinoma of the Pancreas	DOID:4074	8	3.922e-09	3.678e-08
130	Helicobacter Infections	DOID:3686	6	3.951e-09	3.698e-08
131	Colorectal Neoplasms	DOID:1985	7	5.147e-09	4.691e-08
132	Lung Metastases	DOID:2158	6	5.609e-09	5.056e-08
133	Prostatic Neoplasms	DOID:514	9	7.553e-09	6.609e-08
134	Mucocutaneous Lymph Node syndrome	DOID:13378	6	7.804e-09	6.815e-08
135	Severe acute Respiratory syndrome	DOID:2945	6	7.804e-09	6.815e-08
136	Bronchopulmonary Dysplasia	DOID:11651	5	9.724e-09	8.248e-08
137	Dermatomyositis	DOID:10223	5	9.724e-09	8.248e-08
138	Essential Hypertension	DOID:10825	8	1.130e-08	9.412e-08
139	Hepatitis B, chronic	DOID:2042	6	1.434e-08	1.166e-07
140	Neuroendocrine Tumors	DOID:169	6	1.434e-08	1.166e-07
141	Coronary heart disease	DOID:3393	8	1.489e-08	1.205e-07
142	Laryngeal Squamous Cell Carcinoma	DOID:2876	6	1.900e-08	1.483e-07
143	Pulmonary Emphysema	DOID:9675	6	1.900e-08	1.483e-07
144	Endometrial adenocarcinoma	DOID:2870	6	1.900e-08	1.483e-07
145	Lupus Vulgaris	DOID:5380	6	3.211e-08	2.366e-07
146	End stage renal failure	DOID:783	7	3.444e-08	2.517e-07
147	Diabetic Nephropathy	DOID:2370	8	3.632e-08	2.626e-07
148	Age related macular degeneration	DOID:10871	6	4.103e-08	2.917e-07
149	Pulmonary Fibrosis	DOID:3770	6	4.103e-08	2.917e-07
150	Fetal Growth Retardation	DOID:13294	6	4.103e-08	2.917e-07
151	Liver Metastases	DOID:12722	7	4.751e-08	3.303e-07
152	Squamous Cell Carcinoma of Esophagus	DOID:3748	9	5.596e-08	3.819e-07
153	Endometriosis of uterus	DOID:288	5	6.170e-08	4.172e-07
154	Ewings sarcoma	DOID:3369	6	6.503e-08	4.373e-07
155	Adenocarcinoma of Lung	DOID:3910	8	7.207e-08	4.788e-07
156	Lupus erythematosus	DOID:8857	6	8.079e-08	5.282e-07
157	Graves' disease	DOID:12361	7	8.648e-08	5.605e-07
158	Polymyositis	DOID:10222	5	8.920e-08	5.760e-07
159	cardiovascular system disease	DOID:1287	5	8.920e-08	5.760e-07
160	Leukemia, T-Cell	DOID:715	5	8.920e-08	5.760e-07
161	Lung Neoplasms	DOID:3683	7	9.961e-08	6.332e-07
162	Infertility	DOID:5223	7	9.961e-08	6.332e-07
163	acute myocardial infarction	DOID:9408	4	1.031e-07	6.515e-07
164	Down syndrome	DOID:14250	8	1.100e-07	6.913e-07
165	syndrome	DOID:225	12	1.306e-07	8.026e-07
166	Metastatic Melanoma	DOID:4358	6	1.479e-07	8.920e-07
167	Kidney diseases	DOID:557	7	1.703e-07	1.014e-06
168	Uremia	DOID:4676	5	1.729e-07	1.026e-06
169	Retinoblastoma	DOID:768	6	1.785e-07	1.055e-06
170	IGA Glomerulonephritis	DOID:2986	6	1.785e-07	1.055e-06
171	Biliary Atresia	DOID:13608	4	2.051e-07	1.187e-06
172	disease of metabolism	DOID:0014667	5	2.332e-07	1.334e-06
173	Periodontal diseases	DOID:3388	5	2.332e-07	1.334e-06
174	Sarcoidosis	DOID:11335	6	3.030e-07	1.672e-06
175	Proteinuria	DOID:576	5	3.091e-07	1.698e-06
176	malaria, cerebral	DOID:14069	4	3.669e-07	1.966e-06
177	Gingivitis	DOID:3087	4	3.669e-07	1.966e-06
178	Cutaneous Fibrous Histiocytoma	DOID:4418	4	3.669e-07	1.966e-06
179	Epstein-Barr Virus Infections	DOID:2938	5	4.032e-07	2.127e-06
180	Pancreatitis, relapsing	DOID:13315	5	4.032e-07	2.127e-06
181	Transient hypertension of pregnancy	DOID:1257	4	6.080e-07	3.022e-06
182	Influenza	DOID:8469	5	8.271e-07	3.940e-06
183	Dependence	DOID:9973	7	8.297e-07	3.951e-06
184	brucellosis	DOID:11077	4	9.499e-07	4.428e-06
185	Malnutrition	DOID:8452	4	9.499e-07	4.428e-06
186	Pleural Effusion, Malignant	DOID:13906	4	9.499e-07	4.428e-06
187	Leukemia, Lymphocytic, acute	DOID:9952	6	1.010e-06	4.666e-06
188	Cystic Fibrosis	DOID:1485	6	1.155e-06	5.236e-06
189	Carcinoma of larynx	DOID:2600	4	1.417e-06	6.261e-06
190	esotropia	DOID:9840	4	1.417e-06	6.261e-06
191	Kaposi Sarcoma	DOID:8632	5	1.867e-06	7.944e-06
192	Intraocular Melanoma	DOID:6039	5	1.867e-06	7.944e-06
193	Cancer of Skin	DOID:4159	4	2.034e-06	8.530e-06
194	Diabetes, Gestational	DOID:11714	5	2.242e-06	9.264e-06
195	Gastrointestinal Stromal Tumors	DOID:9253	5	2.242e-06	9.264e-06
196	Spontaneous abortion	DOID:722	6	2.419e-06	9.883e-06
197	Familial Mediterranean Fever	DOID:2987	4	2.831e-06	1.132e-05
198	Cancer of Rectum	DOID:1993	4	2.831e-06	1.132e-05
199	Primary biliary cirrhosis	DOID:12236	5	3.170e-06	1.246e-05
200	Papillary thyroid carcinoma	DOID:3969	5	3.734e-06	1.427e-05
201	Polyp of corpus uteri	DOID:9042	3	4.048e-06	1.529e-05
202	Phyllodes Tumor	DOID:2608	3	4.048e-06	1.529e-05
203	Heart diseases	DOID:114	3	4.048e-06	1.529e-05
204	chronic leukemia NOS	DOID:1036	3	4.048e-06	1.529e-05
205	Mucoepidermoid Carcinoma	DOID:4531	3	4.048e-06	1.529e-05
206	Glomerulonephritis	DOID:2921	4	5.088e-06	1.846e-05
207	Bladder Neoplasm	DOID:5428	5	5.098e-06	1.848e-05
208	Diabetes Mellitus, Insulin-Dependent	DOID:9744	5	5.912e-06	2.101e-05
209	Parkinson disease	DOID:14330	7	6.273e-06	2.215e-05
210	Chondrosarcoma	DOID:3371	4	6.615e-06	2.311e-05
211	Hemolytic-Uremic syndrome	DOID:12554	4	6.615e-06	2.311e-05
212	Malignant Pleural Mesothelioma	DOID:7474	4	6.615e-06	2.311e-05
213	Burkitt's tumor or lymphoma	DOID:8584	4	6.615e-06	2.311e-05
214	Basal cell carcinoma	DOID:2513	5	6.824e-06	2.370e-05
215	Malignant neoplasm of liver	DOID:12300	5	7.843e-06	2.664e-05
216	Tropical Spastic Paraparesis	DOID:321	3	8.051e-06	2.726e-05
217	Mycobacterium Infections, Atypical	DOID:412	3	8.051e-06	2.726e-05
218	disease of capillaries	DOID:1271	3	8.051e-06	2.726e-05
219	Kidney Failure, chronic	DOID:784	4	8.456e-06	2.847e-05
220	Gallbladder Carcinoma	DOID:4948	4	8.456e-06	2.847e-05
221	Brain Neoplasms	DOID:1319	5	8.978e-06	2.999e-05
222	Osteoporosis	DOID:11476	5	1.163e-05	3.718e-05
223	malaria, falciparum	DOID:14067	3	1.401e-05	4.333e-05
224	Lymphopenia	DOID:614	3	1.401e-05	4.333e-05
225	Adrenocortical carcinoma	DOID:3948	3	1.401e-05	4.333e-05
226	Primary CNS Lymphoma	DOID:3233	3	1.401e-05	4.333e-05
227	Malignant neoplasm of thyroid	DOID:10008	5	1.485e-05	4.547e-05
228	Huntington disease	DOID:12858	4	1.625e-05	4.905e-05
229	Neurodegenerative disorders	DOID:4874	5	1.671e-05	5.022e-05
230	Heart failure	DOID:6000	6	1.778e-05	5.288e-05
231	Neuromuscular diseases	DOID:440	3	2.230e-05	6.401e-05
232	Bronchial Hyperreactivity	DOID:5783	3	2.230e-05	6.401e-05
233	Schistosoma mansonii infection	DOID:3468	3	2.230e-05	6.401e-05
234	Bronchiolitis Obliterans	DOID:2799	3	2.230e-05	6.401e-05
235	Breast diseases	DOID:3463	3	2.230e-05	6.401e-05
236	acute pancreatitis	DOID:2913	4	2.377e-05	6.753e-05
237	Sarcoma	DOID:1115	4	2.377e-05	6.753e-05
238	Rhabdomyosarcoma	DOID:3247	4	2.836e-05	7.796e-05
239	Cholelithiasis	DOID:10211	4	2.836e-05	7.796e-05
240	Medullary carcinoma of thyroid	DOID:3973	4	2.836e-05	7.796e-05
241	anorexia nervosa	DOID:8689	4	2.836e-05	7.796e-05
242	Myelofibrosis	DOID:4971	4	2.836e-05	7.796e-05
243	acoustic neuroma	DOID:12689	3	3.326e-05	8.906e-05
244	Lyme disease	DOID:11729	3	3.326e-05	8.906e-05
245	Fibroadenoma	DOID:2693	3	3.326e-05	8.906e-05
246	Vasculitis	DOID:865	3	3.326e-05	8.906e-05
247	Takayasu's Arteritis	DOID:13377	3	3.326e-05	8.906e-05
248	Ptosis	DOID:9308	3	3.326e-05	8.906e-05
249	Hyperlipidemia	DOID:1168	4	3.356e-05	8.971e-05
250	Malignant mesothelioma	DOID:1790	4	3.356e-05	8.971e-05
251	Hyperinsulinism	DOID:2018	4	4.602e-05	1.159e-04
252	Thrombocytosis	DOID:2228	3	4.725e-05	1.184e-04
253	Ductal Carcinoma	DOID:3007	5	6.132e-05	1.462e-04
254	Hypercholesterolemia	DOID:2487	4	6.157e-05	1.467e-04
255	Intracranial Aneurysm	DOID:10941	3	6.462e-05	1.526e-04
256	Atrophic gastritis	DOID:8929	3	6.462e-05	1.526e-04
257	Arteriosclerosis	DOID:2349	3	6.462e-05	1.526e-04
258	pancreatitis, alcoholic	DOID:4988	3	6.462e-05	1.526e-04
259	Barrett's esophagus	DOID:9206	4	7.063e-05	1.636e-04
260	Neck Neoplasms	DOID:4725	3	8.568e-05	1.917e-04
261	Osteoarthritis, Knee	DOID:14282	3	8.568e-05	1.917e-04
262	Alopecia Areata	DOID:986	3	8.568e-05	1.917e-04
263	Choriocarcinoma	DOID:3594	3	8.568e-05	1.917e-04
264	Rheumatic Heart disease	DOID:9814	3	8.568e-05	1.917e-04
265	Bone diseases	DOID:1290	3	8.568e-05	1.917e-04
266	Intraepithelial Neoplasia	DOID:5616	3	8.568e-05	1.917e-04
267	Fatty Liver	DOID:9452	3	8.568e-05	1.917e-04
268	Disseminated Malignant Neoplasm	DOID:2332	4	9.160e-05	2.024e-04
269	Acquired Immunodeficiency syndrome	DOID:635	4	9.160e-05	2.024e-04
270	Lipodystrophy	DOID:811	3	1.108e-04	2.355e-04
271	thyroid gland disease	DOID:50	3	1.108e-04	2.355e-04
272	Gouts	DOID:13189	3	1.108e-04	2.355e-04
273	Neurilemmoma	DOID:3192	3	1.108e-04	2.355e-04
274	Yersinia infections	DOID:3300	5	1.256e-04	2.611e-04
275	Liver Cirrhosis	DOID:5082	4	1.311e-04	2.707e-04
276	Purpura, Thrombocytopenic, Idiopathic	DOID:2220	3	1.402e-04	2.863e-04
277	Hereditary Nonpolyposis Colorectal Neoplasms	DOID:3040	3	1.402e-04	2.863e-04
278	Duodenal Ulcer	DOID:1724	3	1.402e-04	2.863e-04
279	Oligodendroglioma	DOID:3181	3	1.402e-04	2.863e-04
280	Gastritis	DOID:4029	3	1.402e-04	2.863e-04
281	Thrombocytopenia	DOID:1588	3	1.743e-04	3.415e-04
282	Labor, Premature	DOID:10875	3	1.743e-04	3.415e-04
283	Myasthenia Gravis	DOID:437	3	1.743e-04	3.415e-04
284	Thrombophilia	DOID:2452	3	2.134e-04	4.019e-04
285	Hypothyroidism	DOID:11630	3	2.134e-04	4.019e-04
286	chronic rejection of renal transplant	DOID:2985	3	2.134e-04	4.019e-04
287	Virus diseases	DOID:934	5	2.321e-04	4.306e-04
288	Premature Birth	DOID:10874	3	2.577e-04	4.688e-04
289	Obesity, Morbid	DOID:11981	3	2.577e-04	4.688e-04
290	chronic sinusitis NOS	DOID:9564	3	3.075e-04	5.402e-04
291	Sezary's disease	DOID:8541	3	3.075e-04	5.402e-04
292	Tuberculosis, Pulmonary	DOID:2957	3	3.075e-04	5.402e-04
293	Medulloblastoma	DOID:3858	4	3.520e-04	6.036e-04
294	Dermatitis, Atopic	DOID:3310	5	4.191e-04	6.958e-04
295	Lymphoproliferative disorders	DOID:619	3	4.249e-04	7.045e-04
296	Sudden infant death syndrome	DOID:9007	3	4.249e-04	7.045e-04
297	chronic simple glaucoma	DOID:1070	3	4.249e-04	7.045e-04
298	Adenocarcinoma, Clear Cell	DOID:4468	3	4.930e-04	7.959e-04
299	Hepatitis	DOID:2237	3	4.930e-04	7.959e-04
300	Pancreatitis	DOID:4989	3	4.930e-04	7.959e-04
301	Osteoporosis, Postmenopausal	DOID:12561	2	5.467e-04	8.650e-04
302	Aortic Aneurysm, Thoracic	DOID:14004	2	5.467e-04	8.650e-04
303	Burning Mouth syndrome	DOID:4331	2	5.467e-04	8.650e-04
304	Klinefelter's syndrome	DOID:1921	2	5.467e-04	8.650e-04
305	Pemphigus	DOID:9182	2	5.467e-04	8.650e-04
306	Leishmaniasis, Visceral	DOID:9146	2	5.467e-04	8.650e-04
307	Urticaria Pigmentosa	DOID:12309	2	5.467e-04	8.650e-04
308	Mastocytosis	DOID:350	2	5.467e-04	8.650e-04
309	Brain Infarction	DOID:3454	2	5.467e-04	8.650e-04
310	Metastatic Adenocarcinoma	DOID:3027	2	5.467e-04	8.650e-04
311	viral hepatitis	DOID:1884	2	5.467e-04	8.650e-04
312	Localized Malignant Neoplasm	DOID:11933	2	5.467e-04	8.650e-04
313	Pituitary Neoplasms	DOID:1785	3	5.678e-04	8.939e-04
314	Kidney Failure	DOID:1074	3	5.678e-04	8.939e-04
315	Ataxia Telangiectasia	DOID:12704	3	6.494e-04	9.973e-04
316	Dermatitis	DOID:2723	3	6.494e-04	9.973e-04
317	Amyotrophic Lateral Sclerosis	DOID:332	4	7.092e-04	1.072e-03
318	Bone Metastases	DOID:2759	3	7.381e-04	1.104e-03
319	Azoospermia	DOID:14227	3	7.381e-04	1.104e-03
320	Thromboangiitis Obliterans	DOID:12918	2	8.161e-04	1.202e-03
321	Adenoma of Parathyroid	DOID:7608	2	8.161e-04	1.202e-03
322	Refractory Cancer	DOID:5666	2	8.161e-04	1.202e-03
323	Malignant neoplasm of tongue, unspecified	DOID:8649	2	8.161e-04	1.202e-03
324	Malignant neoplasm of male breast	DOID:9796	2	8.161e-04	1.202e-03
325	Mycobacterium Infections	DOID:2757	2	8.161e-04	1.202e-03
326	Chordoma	DOID:3302	2	8.161e-04	1.202e-03
327	Adenocarcinoma of Rectum	DOID:1996	2	8.161e-04	1.202e-03
328	Sicca syndrome	DOID:416	3	9.378e-04	1.349e-03
329	Herpangina	DOID:10883	3	9.378e-04	1.349e-03
330	Solid Tumor	DOID:5650	3	1.049e-03	1.481e-03
331	Neoplasm, Thyroid	DOID:1781	3	1.049e-03	1.481e-03
332	Carcinoma, Papillary	DOID:3113	3	1.049e-03	1.481e-03
333	Sarcoma, Clear Cell	DOID:4233	2	1.137e-03	1.581e-03
334	Recurrent Cancer of Prostate	DOID:8045	2	1.137e-03	1.581e-03
335	Uterine Cancer	DOID:4363	2	1.137e-03	1.581e-03
336	nervous system disease	DOID:863	2	1.137e-03	1.581e-03
337	Angiomyolipoma	DOID:3314	2	1.137e-03	1.581e-03
338	Eosinophilia	DOID:999	2	1.137e-03	1.581e-03
339	Myoma	DOID:2691	2	1.137e-03	1.581e-03
340	Extramammary Paget's disease	DOID:2099	2	1.137e-03	1.581e-03
341	Glaucoma	DOID:1686	3	1.169e-03	1.618e-03
342	pneumonia	DOID:552	3	1.169e-03	1.618e-03
343	Migraine	DOID:6364	3	1.297e-03	1.764e-03
344	Vascular diseases	DOID:178	3	1.297e-03	1.764e-03
345	Coronary Stenosis	DOID:4248	2	1.508e-03	2.004e-03
346	Squamous cell carcinoma of skin	DOID:3151	2	1.508e-03	2.004e-03
347	Metabolic syndrome X	DOID:14221	2	1.508e-03	2.004e-03
348	Bronchiolitis	DOID:2942	2	1.508e-03	2.004e-03
349	CNS metastases	DOID:928	2	1.508e-03	2.004e-03
350	Fibrosarcoma	DOID:3355	2	1.508e-03	2.004e-03
351	Abortion, Habitual	DOID:11946	2	1.508e-03	2.004e-03
352	polyphagia	DOID:8669	3	1.578e-03	2.082e-03
353	autistic disorder	DOID:12849	4	1.685e-03	2.202e-03
354	Neoplasm, Pancreatic	DOID:3588	3	1.731e-03	2.254e-03
355	Liver diseases	DOID:409	3	1.894e-03	2.434e-03
356	Leiomyosarcoma	DOID:1967	2	1.930e-03	2.474e-03
357	Cervical Adenocarcinoma	DOID:3702	2	1.930e-03	2.474e-03
358	Metaplastic Polyp	DOID:6443	2	1.930e-03	2.474e-03
359	Intermediate coronary syndrome	DOID:8805	2	1.930e-03	2.474e-03
360	Polycythemia	DOID:8432	2	1.930e-03	2.474e-03
361	Stage I NSCLC	DOID:4820	2	1.930e-03	2.474e-03
362	Respiratory Syncytial Virus Infections	DOID:1273	2	1.930e-03	2.474e-03
363	Respiratory Distress syndrome, Newborn	DOID:11395	2	1.930e-03	2.474e-03
364	Retinal diseases	DOID:5679	3	2.248e-03	2.820e-03
365	Pseudoxanthoma Elasticum	DOID:2738	2	2.401e-03	2.976e-03
366	Cushing syndrome	DOID:12252	2	2.401e-03	2.976e-03
367	Muscular Dystrophy, Duchenne	DOID:11723	2	2.401e-03	2.976e-03
368	Henoch-Schoenlein Purpura	DOID:11123	2	2.401e-03	2.976e-03
369	Uveitis	DOID:13141	2	2.401e-03	2.976e-03
370	hepatitis B	DOID:2043	2	2.401e-03	2.976e-03
371	Thalassemia	DOID:10241	2	2.401e-03	2.976e-03
372	Leukoencephalopathy, Progressive Multifocal	DOID:643	3	2.439e-03	3.017e-03
373	dementia	DOID:1307	3	2.639e-03	3.231e-03
374	Hyperglycemia	DOID:4195	3	2.850e-03	3.456e-03
375	Pancreatic carcinoma	DOID:4905	3	2.850e-03	3.456e-03
376	Severe Combined Immunodeficiency	DOID:627	2	2.920e-03	3.530e-03
377	Thrombophlebitis	DOID:3875	2	2.920e-03	3.530e-03
378	Metastatic malignant neoplasm to brain	DOID:927	2	2.920e-03	3.530e-03
379	Atrophic condition of skin	DOID:2733	2	2.920e-03	3.530e-03
380	Thrombocythemia, Hemorrhagic	DOID:2224	2	2.920e-03	3.530e-03
381	Rabies	DOID:11260	4	3.194e-03	3.819e-03
382	Respiratory Distress syndrome, Adult	DOID:11394	2	3.486e-03	4.117e-03
383	Ependymoma	DOID:4844	2	4.100e-03	4.765e-03
384	Encephalitis	DOID:9588	2	4.100e-03	4.765e-03
385	Leprosy	DOID:1024	2	4.100e-03	4.765e-03
386	Myeloproliferative disease	DOID:2356	2	4.100e-03	4.765e-03
387	Infection of amniotic sac and membranes	DOID:13429	2	4.760e-03	5.435e-03
388	Hyperandrogenism	DOID:11613	2	4.760e-03	5.435e-03
389	Sarcoma, Synovial	DOID:5485	2	4.760e-03	5.435e-03
390	Alopecia	DOID:987	2	4.760e-03	5.435e-03
391	tuberous sclerosis	DOID:13515	2	5.466e-03	6.160e-03
392	Seminoma	DOID:4440	2	5.466e-03	6.160e-03
393	Adenoid Cystic Carcinoma	DOID:4866	2	5.466e-03	6.160e-03
394	Kidney Neoplasms	DOID:263	2	6.216e-03	6.923e-03
395	Carcinoma, Endometrioid	DOID:3000	2	7.010e-03	7.718e-03
396	Skin Melanoma	DOID:8923	2	7.010e-03	7.718e-03
397	Mesothelioma	DOID:2645	2	7.848e-03	8.563e-03
398	Malignant neoplasm of gallbladder	DOID:8090	2	7.848e-03	8.563e-03
399	mental depression	DOID:1596	3	8.493e-03	9.201e-03
400	Spinal Dysraphism	DOID:1089	2	8.729e-03	9.439e-03
401	Cystadenocarcinoma, Serous	DOID:3114	2	9.651e-03	1.037e-02
402	Malignant neoplasm of kidney	DOID:3676	2	9.651e-03	1.037e-02
403	Cerebral Infarction	DOID:3526	2	1.062e-02	1.133e-02
404	Myocardial Ischemia	DOID:3394	2	1.062e-02	1.133e-02
405	Vitiligo	DOID:12306	2	1.062e-02	1.133e-02
406	Carcinoma of bladder	DOID:4007	2	1.162e-02	1.234e-02
407	neuropathy	DOID:870	2	1.375e-02	1.447e-02
408	attention deficit hyperactivity disorder	DOID:1094	2	1.603e-02	1.673e-02
409	Lung diseases	DOID:850	2	1.603e-02	1.673e-02
410	Sickle Cell Anemia	DOID:10923	2	1.723e-02	1.792e-02
411	Amyloidosis	DOID:9120	2	1.723e-02	1.792e-02
412	Adenocarcinoma of the Colon	DOID:234	2	1.847e-02	1.915e-02
413	Adenocarcinoma of Prostate	DOID:2526	2	1.847e-02	1.915e-02
414	Hypertension, Pulmonary	DOID:6432	2	1.974e-02	2.041e-02
415	Heart Failure, Congestive	DOID:395	2	2.239e-02	2.304e-02
416	Asthma, allergic NOS	DOID:9415	2	2.961e-02	3.020e-02
417	alcoholic intoxication, chronic	DOID:1598	2	3.596e-02	3.648e-02

- KEGG pathway/disease terms

#	Description	Term ID	# of overlapped genes	P value	FDR

1	Jak-STAT signaling pathway	hsa04630	30	8.017e-34	1.830e-31
2	Pathways in cancer	hsa05200	35	1.446e-27	1.787e-25
3	Measles	hsa05162	22	1.809e-23	1.583e-21
4	PI3K-Akt signaling pathway	hsa04151	29	2.814e-22	2.291e-20
5	Hepatitis B	hsa05161	20	8.628e-20	5.884e-18
6	Cytokine-cytokine receptor interaction	hsa04060	22	6.085e-17	3.117e-15
7	Bladder cancer	hsa05219	12	1.781e-16	8.533e-15
8	Proteoglycans in cancer	hsa05205	18	1.569e-14	5.991e-13
9	FoxO signaling pathway	hsa04068	15	8.955e-14	2.970e-12
10	TNF signaling pathway	hsa04668	14	1.042e-13	3.387e-12
11	Influenza A	hsa05164	16	3.063e-13	9.113e-12
12	HTLV-I infection	hsa05166	18	9.637e-13	2.642e-11
13	Rheumatoid arthritis	hsa05323	12	3.247e-12	8.001e-11
14	Melanoma	hsa05218	11	5.758e-12	1.347e-10
15	Transcriptional misregulation in cancer	hsa05202	15	6.195e-12	1.436e-10
16	Prolactin signaling pathway	hsa04917	11	6.737e-12	1.552e-10
17	Herpes simplex infection	hsa05168	15	9.203e-12	2.061e-10
18	MicroRNAs in cancer	hsa05206	18	1.020e-11	2.265e-10
19	HIF-1 signaling pathway	hsa04066	12	1.874e-11	3.977e-10
20	Chagas disease (American trypanosomiasis)	hsa05142	12	2.103e-11	4.443e-10
21	Hepatitis C	hsa05160	13	2.456e-11	5.107e-10
22	Malaria	hsa05144	9	1.105e-10	2.015e-09
23	Small cell lung cancer	hsa05222	10	9.862e-10	1.429e-08
24	Toxoplasmosis	hsa05145	11	1.488e-09	2.070e-08
25	Pancreatic cancer	hsa05212	9	1.693e-09	2.318e-08
26	p53 signaling pathway	hsa04115	9	2.216e-09	2.931e-08
27	Leishmaniasis	hsa05140	9	3.701e-09	4.655e-08
28	Epstein-Barr virus infection	hsa05169	13	3.825e-09	4.798e-08
29	Chronic myeloid leukemia	hsa05220	9	4.187e-09	5.179e-08
30	Osteoclast differentiation	hsa04380	11	4.498e-09	5.492e-08
31	Colorectal cancer	hsa05210	8	2.211e-08	2.297e-07
32	Prostate cancer	hsa05215	9	2.417e-08	2.477e-07
33	Endometrial cancer	hsa05213	7	1.310e-07	1.087e-06
34	African trypanosomiasis	hsa05143	6	2.142e-07	1.680e-06
35	Non-alcoholic fatty liver disease (NAFLD)	hsa04932	10	2.185e-07	1.705e-06
36	Apoptosis	hsa04210	8	2.621e-07	2.011e-06
37	Cell cycle	hsa04110	9	4.192e-07	3.028e-06
38	Focal adhesion	hsa04510	11	4.831e-07	3.414e-06
39	MAPK signaling pathway	hsa04010	12	5.232e-07	3.666e-06
40	Glioma	hsa05214	7	6.102e-07	4.180e-06
41	Inflammatory bowel disease (IBD)	hsa05321	7	6.102e-07	4.180e-06
42	Central carbon metabolism in cancer	hsa05230	7	7.502e-07	4.993e-06
43	Tuberculosis	hsa05152	10	9.398e-07	6.044e-06
44	Toll-like receptor signaling pathway	hsa04620	8	1.411e-06	8.525e-06
45	Hippo signaling pathway	hsa04390	9	2.547e-06	1.403e-05
46	Rap1 signaling pathway	hsa04015	10	4.535e-06	2.273e-05
47	NF-kappa B signaling pathway	hsa04064	7	5.837e-06	2.811e-05
48	Estrogen signaling pathway	hsa04915	7	1.015e-05	4.547e-05
49	Renal cell carcinoma	hsa05211	6	1.081e-05	4.804e-05
50	Complement and coagulation cascades	hsa04610	6	1.395e-05	5.962e-05
51	T cell receptor signaling pathway	hsa04660	7	1.399e-05	5.964e-05
52	Adipocytokine signaling pathway	hsa04920	6	1.514e-05	6.385e-05
53	Pertussis	hsa05133	6	2.242e-05	8.891e-05
54	Viral carcinogenesis	hsa05203	9	2.533e-05	9.841e-05
55	Ras signaling pathway	hsa04014	9	5.590e-05	1.910e-04
56	Non-small cell lung cancer	hsa05223	5	6.681e-05	2.218e-04
57	Natural killer cell mediated cytotoxicity	hsa04650	7	7.060e-05	2.329e-04
58	Thyroid cancer	hsa05216	4	7.063e-05	2.330e-04
59	Acute myeloid leukemia	hsa05221	5	7.268e-05	2.382e-04
60	Chemokine signaling pathway	hsa04062	8	8.662e-05	2.756e-04
61	mTOR signaling pathway	hsa04150	5	9.268e-05	2.909e-04
62	Wnt signaling pathway	hsa04310	7	9.706e-05	3.025e-04
63	Amoebiasis	hsa05146	6	1.697e-04	4.725e-04
64	Allograft rejection	hsa05330	4	1.816e-04	4.988e-04
65	Graft-versus-host disease	hsa05332	4	2.691e-04	6.763e-04
66	Thyroid hormone signaling pathway	hsa04919	6	2.735e-04	6.852e-04
67	Intestinal immune network for IgA production	hsa04672	4	4.518e-04	1.016e-03
68	Salmonella infection	hsa05132	5	4.927e-04	1.092e-03
69	ErbB signaling pathway	hsa04012	5	5.192e-04	1.138e-03
70	Signaling pathways regulating pluripotency of stem cells	hsa04550	6	7.271e-04	1.490e-03
71	Staphylococcus aureus infection	hsa05150	4	8.142e-04	1.624e-03
72	VEGF signaling pathway	hsa04370	4	1.195e-03	2.211e-03
73	Insulin resistance	hsa04931	5	1.423e-03	2.549e-03
74	Sphingolipid signaling pathway	hsa04071	5	2.165e-03	3.560e-03
75	Adherens junction	hsa04520	4	2.299e-03	3.750e-03
76	TGF-beta signaling pathway	hsa04350	4	3.799e-03	5.609e-03
77	Hematopoietic cell lineage	hsa04640	4	4.300e-03	6.203e-03
78	Type I diabetes mellitus	hsa04940	3	4.331e-03	6.242e-03
79	Oxytocin signaling pathway	hsa04921	5	6.910e-03	9.261e-03
80	Amyotrophic lateral sclerosis (ALS)	hsa05014	3	6.919e-03	9.270e-03
81	Mineral absorption	hsa04978	3	6.919e-03	9.270e-03
82	Choline metabolism in cancer	hsa05231	4	7.233e-03	9.637e-03
83	Autoimmune thyroid disease	hsa05320	3	7.295e-03	9.703e-03
84	Legionellosis	hsa05134	3	8.493e-03	1.102e-02
85	NOD-like receptor signaling pathway	hsa04621	3	9.352e-03	1.198e-02
86	Cholinergic synapse	hsa04725	4	9.985e-03	1.267e-02
87	Leukocyte transendothelial migration	hsa04670	4	1.227e-02	1.515e-02
88	AMPK signaling pathway	hsa04152	4	1.447e-02	1.753e-02
89	B cell receptor signaling pathway	hsa04662	3	1.739e-02	2.059e-02
90	Dorso-ventral axis formation	hsa04320	2	1.847e-02	2.171e-02
91	Asthma	hsa05310	2	2.239e-02	2.581e-02
92	Phospholipase D signaling pathway	hsa04072	4	2.303e-02	2.647e-02
93	GnRH signaling pathway	hsa04912	3	3.171e-02	3.534e-02
94	Proteasome	hsa03050	2	4.456e-02	4.850e-02

- Gene Ontology biological process terms

#	Description	Term ID	# of overlapped genes	P value	FDR

1	positive regulation of transcription from RNA polymerase II promoter	GO:0045944	34	3.050e-21	1.568e-18
2	positive regulation of cell proliferation	GO:0008284	27	1.124e-19	4.662e-17
3	anti-apoptosis	GO:0006916	21	2.655e-18	8.716e-16
4	response to drug	GO:0042493	22	2.436e-16	5.937e-14
5	response to hypoxia	GO:0001666	18	5.031e-16	1.133e-13
6	negative regulation of cell proliferation	GO:0008285	23	6.350e-16	1.390e-13
7	response to cytokine stimulus	GO:0034097	12	2.009e-14	3.209e-12
8	response to organic cyclic compound	GO:0014070	14	3.120e-14	4.758e-12
9	negative regulation of apoptotic process	GO:0043066	19	8.166e-14	1.122e-11
10	negative regulation of transcription from RNA polymerase II promoter	GO:0000122	22	6.862e-13	7.652e-11
11	cytokine-mediated signaling pathway	GO:0019221	17	9.618e-13	1.024e-10
12	positive regulation of smooth muscle cell proliferation	GO:0048661	9	1.002e-11	8.585e-10
13	positive regulation of protein phosphorylation	GO:0001934	11	2.867e-11	2.165e-09
14	signal transduction	GO:0007165	33	3.567e-11	2.615e-09
15	response to heat	GO:0009408	9	9.120e-11	5.972e-09
16	angiogenesis	GO:0001525	13	1.971e-10	1.179e-08
17	response to lipopolysaccharide	GO:0032496	12	2.207e-10	1.301e-08
18	cellular response to interleukin-1	GO:0071347	7	2.513e-10	1.463e-08
19	response to estradiol stimulus	GO:0032355	10	6.937e-10	3.482e-08
20	negative regulation of cell growth	GO:0030308	11	7.031e-10	3.521e-08
21	response to peptide hormone stimulus	GO:0043434	9	7.134e-10	3.550e-08
22	positive regulation of cell division	GO:0051781	8	1.141e-09	5.227e-08
23	regulation of interferon-gamma-mediated signaling pathway	GO:0060334	6	1.188e-09	5.421e-08
24	positive regulation of angiogenesis	GO:0045766	9	1.693e-09	7.331e-08
25	interferon-gamma-mediated signaling pathway	GO:0060333	9	2.216e-09	9.142e-08
26	positive regulation of nitric oxide biosynthetic process	GO:0045429	7	2.564e-09	1.040e-07
27	platelet activation	GO:0030168	13	4.855e-09	1.830e-07
28	positive regulation of peptidyl-serine phosphorylation	GO:0033138	7	6.394e-09	2.270e-07
29	collagen catabolic process	GO:0030574	6	7.804e-09	2.678e-07
30	response to glucocorticoid stimulus	GO:0051384	9	1.055e-08	3.469e-07
31	response to corticosterone stimulus	GO:0051412	6	1.434e-08	4.484e-07
32	JAK-STAT cascade involved in growth hormone signaling pathway	GO:0060397	6	1.900e-08	5.658e-07
33	positive regulation of peptidyl-tyrosine phosphorylation	GO:0050731	8	1.943e-08	5.756e-07
34	ovarian follicle development	GO:0001541	7	2.455e-08	6.960e-07
35	response to progesterone stimulus	GO:0032570	6	2.485e-08	7.019e-07
36	apoptotic process	GO:0006915	20	2.598e-08	7.295e-07
37	type I interferon-mediated signaling pathway	GO:0060337	8	2.846e-08	7.787e-07
38	response to mechanical stimulus	GO:0009612	7	4.054e-08	1.050e-06
39	positive regulation of epithelial cell proliferation	GO:0050679	7	4.054e-08	1.050e-06
40	JAK-STAT cascade	GO:0007259	6	4.103e-08	1.060e-06
41	regulation of type I interferon-mediated signaling pathway	GO:0060338	6	4.103e-08	1.060e-06
42	response to gamma radiation	GO:0010332	6	5.190e-08	1.290e-06
43	positive regulation of apoptotic process	GO:0043065	11	5.573e-08	1.362e-06
44	inflammatory response	GO:0006954	13	5.935e-08	1.426e-06
45	positive regulation of transcription, DNA-dependent	GO:0045893	17	7.672e-08	1.759e-06
46	organ regeneration	GO:0031100	7	8.648e-08	1.941e-06
47	platelet degranulation	GO:0002576	8	1.487e-07	3.000e-06
48	response to ethanol	GO:0045471	8	2.392e-07	4.478e-06
49	positive regulation of MAPK cascade	GO:0043410	7	2.476e-07	4.612e-06
50	response to insulin stimulus	GO:0032868	7	3.141e-07	5.588e-06
51	blood coagulation	GO:0007596	16	3.294e-07	5.811e-06
52	response to DNA damage stimulus	GO:0006974	9	3.408e-07	5.986e-06
53	protein import into nucleus, translocation	GO:0000060	5	4.032e-07	6.852e-06
54	cellular response to hypoxia	GO:0071456	6	4.200e-07	7.087e-06
55	positive regulation of anti-apoptosis	GO:0045768	6	4.200e-07	7.087e-06
56	regulation of cell cycle	GO:0051726	7	4.417e-07	7.369e-06
57	cell cycle arrest	GO:0007050	9	5.848e-07	9.168e-06
58	cell proliferation	GO:0008283	13	5.916e-07	9.256e-06
59	positive regulation of interleukin-17 production	GO:0032740	4	9.499e-07	1.350e-05
60	cell morphogenesis	GO:0000902	6	1.010e-06	1.416e-05
61	vascular endothelial growth factor receptor signaling pathway	GO:0048010	5	1.028e-06	1.430e-05
62	cell aging	GO:0007569	5	1.028e-06	1.430e-05
63	female pregnancy	GO:0007565	7	1.112e-06	1.524e-05
64	positive regulation of ERK1 and ERK2 cascade	GO:0070374	7	1.470e-06	1.891e-05
65	response to radiation	GO:0009314	5	1.543e-06	1.960e-05
66	lung development	GO:0030324	7	1.609e-06	2.019e-05
67	positive regulation of endothelial cell proliferation	GO:0001938	6	1.912e-06	2.301e-05
68	regulation of apoptotic process	GO:0042981	10	2.149e-06	2.514e-05
69	positive regulation of mesenchymal cell proliferation	GO:0002053	5	2.242e-06	2.604e-05
70	cellular response to tumor necrosis factor	GO:0071356	5	2.242e-06	2.604e-05
71	positive regulation of blood vessel endothelial cell migration	GO:0043536	4	2.831e-06	3.112e-05
72	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	GO:0043619	3	4.048e-06	4.053e-05
73	cellular response to amino acid stimulus	GO:0071230	5	4.375e-06	4.305e-05
74	cellular response to lithium ion	GO:0071285	4	5.088e-06	4.835e-05
75	response to estrogen stimulus	GO:0043627	6	5.664e-06	5.265e-05
76	intracellular protein kinase cascade	GO:0007243	7	6.273e-06	5.693e-05
77	humoral immune response	GO:0006959	5	7.843e-06	6.658e-05
78	activation-induced cell death of T cells	GO:0006924	3	8.051e-06	6.785e-05
79	induction of apoptosis	GO:0006917	9	9.441e-06	7.677e-05
80	positive regulation of cell death	GO:0010942	4	1.065e-05	8.391e-05
81	positive regulation of gene expression	GO:0010628	7	1.156e-05	8.884e-05
82	positive regulation of cell migration	GO:0030335	7	1.156e-05	8.884e-05
83	response to oxidative stress	GO:0006979	7	1.314e-05	9.815e-05
84	negative regulation of inflammatory response	GO:0050728	5	1.316e-05	9.832e-05
85	reactive oxygen species metabolic process	GO:0072593	4	1.323e-05	9.878e-05
86	cell-cell signaling	GO:0007267	10	1.396e-05	1.025e-04
87	positive regulation of cyclin-dependent protein kinase activity involved in G1/S	GO:0031659	3	1.401e-05	1.027e-04
88	prostate gland growth	GO:0060736	3	1.401e-05	1.027e-04
89	protein autophosphorylation	GO:0046777	8	1.500e-05	1.080e-04
90	aging	GO:0007568	7	1.583e-05	1.125e-04
91	response to bacterium	GO:0009617	4	1.625e-05	1.150e-04
92	negative regulation of T cell proliferation	GO:0042130	4	1.625e-05	1.150e-04
93	cellular response to lipopolysaccharide	GO:0071222	5	1.671e-05	1.173e-04
94	induction of apoptosis by intracellular signals	GO:0008629	5	1.874e-05	1.273e-04
95	immune response	GO:0006955	12	1.940e-05	1.307e-04
96	positive regulation of cyclin-dependent protein kinase activity	GO:0045737	3	2.230e-05	1.448e-04
97	positive regulation of protein kinase B signaling cascade	GO:0051897	5	2.337e-05	1.497e-04
98	embryonic placenta development	GO:0001892	4	2.836e-05	1.718e-04
99	response to cAMP	GO:0051591	5	2.884e-05	1.740e-04
100	defense response to virus	GO:0051607	5	2.884e-05	1.740e-04
101	positive regulation of chemokine biosynthetic process	GO:0045080	3	3.326e-05	1.932e-04
102	mitotic cell cycle G1/S transition DNA damage checkpoint	GO:0031571	3	3.326e-05	1.932e-04
103	response to tumor necrosis factor	GO:0034612	4	3.356e-05	1.942e-04
104	protein phosphorylation	GO:0006468	12	3.446e-05	1.983e-04
105	innate immune response	GO:0045087	11	3.624e-05	2.036e-04
106	response to cold	GO:0009409	4	3.943e-05	2.163e-04
107	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	GO:0043280	4	3.943e-05	2.163e-04
108	negative regulation of transcription, DNA-dependent	GO:0045892	12	4.102e-05	2.221e-04
109	neutrophil chemotaxis	GO:0030593	4	4.602e-05	2.424e-04
110	lipopolysaccharide-mediated signaling pathway	GO:0031663	4	4.602e-05	2.424e-04
111	response to amino acid stimulus	GO:0043200	4	4.602e-05	2.424e-04
112	regulation of mitochondrial membrane permeability	GO:0046902	3	4.725e-05	2.476e-04
113	negative regulation of sequence-specific DNA binding transcription factor activity	GO:0043433	5	5.138e-05	2.620e-04
114	response to antibiotic	GO:0046677	4	5.338e-05	2.688e-04
115	proteolysis	GO:0006508	14	5.452e-05	2.732e-04
116	regulation of inflammatory response	GO:0050727	4	6.157e-05	2.973e-04
117	cellular response to fibroblast growth factor stimulus	GO:0044344	3	6.462e-05	3.083e-04
118	negative regulation of hormone secretion	GO:0046888	3	6.462e-05	3.083e-04
119	induction of positive chemotaxis	GO:0050930	3	6.462e-05	3.083e-04
120	positive regulation of tumor necrosis factor production	GO:0032760	4	7.063e-05	3.269e-04
121	positive regulation of cell adhesion	GO:0045785	4	7.063e-05	3.269e-04
122	positive regulation of MAP kinase activity	GO:0043406	4	8.062e-05	3.584e-04
123	positive regulation of I-kappaB kinase/NF-kappaB cascade	GO:0043123	7	8.879e-05	3.840e-04
124	branching involved in ureteric bud morphogenesis	GO:0001658	4	9.160e-05	3.943e-04
125	response to organic nitrogen	GO:0010243	4	9.160e-05	3.943e-04
126	activation of pro-apoptotic gene products	GO:0008633	4	9.160e-05	3.943e-04
127	negative regulation of macrophage derived foam cell differentiation	GO:0010745	3	1.108e-04	4.514e-04
128	cellular iron ion homeostasis	GO:0006879	5	1.167e-04	4.662e-04
129	positive regulation of B cell proliferation	GO:0030890	4	1.168e-04	4.665e-04
130	intracellular receptor mediated signaling pathway	GO:0030522	4	1.168e-04	4.665e-04
131	response to glucose stimulus	GO:0009749	5	1.351e-04	5.172e-04
132	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	GO:0006978	3	1.402e-04	5.312e-04
133	positive regulation of collagen biosynthetic process	GO:0032967	3	1.402e-04	5.312e-04
134	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	GO:0006977	5	1.451e-04	5.438e-04
135	response to toxin	GO:0009636	5	1.557e-04	5.712e-04
136	male gonad development	GO:0008584	5	1.557e-04	5.712e-04
137	negative regulation of epithelial cell proliferation	GO:0050680	4	1.634e-04	5.910e-04
138	acute-phase response	GO:0006953	4	1.634e-04	5.910e-04
139	mammary gland alveolus development	GO:0060749	3	1.743e-04	6.188e-04
140	superoxide anion generation	GO:0042554	3	1.743e-04	6.188e-04
141	response to copper ion	GO:0046688	3	1.743e-04	6.188e-04
142	negative regulation of growth of symbiont in host	GO:0044130	3	1.743e-04	6.188e-04
143	positive regulation of phosphatidylinositol 3-kinase cascade	GO:0014068	4	1.816e-04	6.359e-04
144	positive regulation of fibroblast proliferation	GO:0048146	4	2.012e-04	6.814e-04
145	G1 phase of mitotic cell cycle	GO:0000080	4	2.012e-04	6.814e-04
146	B cell differentiation	GO:0030183	4	2.012e-04	6.814e-04
147	negative regulation of cell differentiation	GO:0045596	3	2.134e-04	7.106e-04
148	positive regulation of vascular endothelial growth factor receptor signaling pathway	GO:0030949	3	2.134e-04	7.106e-04
149	negative regulation of mitotic cell cycle	GO:0045930	3	2.134e-04	7.106e-04
150	positive regulation vascular endothelial growth factor production	GO:0010575	3	2.134e-04	7.106e-04
151	response to stress	GO:0006950	7	2.369e-04	7.655e-04
152	regulation of gene expression	GO:0010468	4	2.449e-04	7.859e-04
153	cell surface receptor signaling pathway	GO:0007166	7	2.459e-04	7.877e-04
154	decidualization	GO:0046697	3	2.577e-04	8.164e-04
155	negative regulation of neuron apoptosis	GO:0043524	5	2.631e-04	8.294e-04
156	in utero embryonic development	GO:0001701	7	2.646e-04	8.328e-04
157	T cell homeostasis	GO:0043029	3	3.075e-04	9.247e-04
158	endoplasmic reticulum unfolded protein response	GO:0030968	5	3.152e-04	9.408e-04
159	chemotaxis	GO:0006935	6	3.564e-04	1.031e-03
160	positive regulation of activated T cell proliferation	GO:0042104	3	3.632e-04	1.043e-03
161	response to X-ray	GO:0010165	3	3.632e-04	1.043e-03
162	regulation of nitric-oxide synthase activity	GO:0050999	3	3.632e-04	1.043e-03
163	regulation of protein stability	GO:0031647	3	3.632e-04	1.043e-03
164	regulation of catalytic activity	GO:0050790	4	3.833e-04	1.085e-03
165	cellular response to UV	GO:0034644	3	4.249e-04	1.164e-03
166	positive regulation of vasoconstriction	GO:0045907	3	4.930e-04	1.303e-03
167	positive chemotaxis	GO:0050918	3	4.930e-04	1.303e-03
168	positive regulation of intracellular protein kinase cascade	GO:0010740	2	5.467e-04	1.400e-03
169	STAT protein import into nucleus	GO:0007262	2	5.467e-04	1.400e-03
170	negative regulation of B cell apoptosis	GO:0002903	2	5.467e-04	1.400e-03
171	positive regulation of interleukin-23 production	GO:0032747	2	5.467e-04	1.400e-03
172	negative regulation of skeletal muscle tissue development	GO:0048642	2	5.467e-04	1.400e-03
173	mRNA transcription from RNA polymerase II promoter	GO:0042789	2	5.467e-04	1.400e-03
174	response to peptidoglycan	GO:0032494	2	5.467e-04	1.400e-03
175	tissue remodeling	GO:0048771	2	5.467e-04	1.400e-03
176	positive regulation of mast cell chemotaxis	GO:0060754	2	5.467e-04	1.400e-03
177	response to nicotine	GO:0035094	3	5.678e-04	1.441e-03
178	positive regulation of reactive oxygen species metabolic process	GO:2000379	3	5.678e-04	1.441e-03
179	negative regulation of DNA replication	GO:0008156	3	5.678e-04	1.441e-03
180	regulation of protein phosphorylation	GO:0001932	3	5.678e-04	1.441e-03
181	release of cytochrome c from mitochondria	GO:0001836	3	5.678e-04	1.441e-03
182	regulation of angiogenesis	GO:0045765	3	5.678e-04	1.441e-03
183	cellular response to mechanical stimulus	GO:0071260	4	5.702e-04	1.443e-03
184	peptidyl-tyrosine phosphorylation	GO:0018108	4	5.702e-04	1.443e-03
185	regulation of cell shape	GO:0008360	5	6.054e-04	1.510e-03
186	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	GO:0043154	4	6.142e-04	1.521e-03
187	positive regulation of phosphatidylinositol 3-kinase activity	GO:0043552	3	6.494e-04	1.588e-03
188	positive regulation of cell differentiation	GO:0045597	3	6.494e-04	1.588e-03
189	inner ear development	GO:0048839	3	6.494e-04	1.588e-03
190	cell differentiation	GO:0030154	12	6.589e-04	1.606e-03
191	regulation of cyclin-dependent protein kinase activity	GO:0000079	4	6.605e-04	1.607e-03
192	cellular component movement	GO:0006928	5	7.019e-04	1.680e-03
193	elevation of cytosolic calcium ion concentration	GO:0007204	5	7.365e-04	1.738e-03
194	positive regulation of NF-kappaB transcription factor activity	GO:0051092	5	7.365e-04	1.738e-03
195	regulation of cell proliferation	GO:0042127	5	7.365e-04	1.738e-03
196	positive regulation of phosphorylation	GO:0042327	3	7.381e-04	1.739e-03
197	positive regulation of tyrosine phosphorylation of Stat3 protein	GO:0042517	3	7.381e-04	1.739e-03
198	response to virus	GO:0009615	6	7.541e-04	1.769e-03
199	cellular response to insulin stimulus	GO:0032869	4	7.605e-04	1.779e-03
200	regulation of blood pressure	GO:0008217	4	7.605e-04	1.779e-03
201	organ morphogenesis	GO:0009887	5	7.724e-04	1.801e-03
202	G-protein coupled receptor signaling pathway	GO:0007186	9	7.736e-04	1.803e-03
203	G1/S transition of mitotic cell cycle	GO:0000082	6	7.819e-04	1.814e-03
204	negative regulation of lipid storage	GO:0010888	2	8.161e-04	1.876e-03
205	response to interleukin-4	GO:0070670	2	8.161e-04	1.876e-03
206	negative regulation of focal adhesion assembly	GO:0051895	2	8.161e-04	1.876e-03
207	positive regulation of synaptic plasticity	GO:0031915	2	8.161e-04	1.876e-03
208	signal transduction by p53 class mediator resulting in induction of apoptosis	GO:0072332	2	8.161e-04	1.876e-03
209	positive regulation of isotype switching to IgG isotypes	GO:0048304	2	8.161e-04	1.876e-03
210	epithelial cell proliferation involved in salivary gland morphogenesis	GO:0060664	2	8.161e-04	1.876e-03
211	positive regulation of DNA biosynthetic process	GO:2000573	2	8.161e-04	1.876e-03
212	positive regulation of cell migration involved in sprouting angiogenesis	GO:0090050	2	8.161e-04	1.876e-03
213	positive regulation of interleukin-12 biosynthetic process	GO:0045084	2	8.161e-04	1.876e-03
214	positive regulation of vascular permeability	GO:0043117	2	8.161e-04	1.876e-03
215	salivary gland morphogenesis	GO:0007435	2	8.161e-04	1.876e-03
216	positive regulation of histone deacetylation	GO:0031065	2	8.161e-04	1.876e-03
217	negative regulation of phosphorylation	GO:0042326	3	8.342e-04	1.907e-03
218	negative regulation of DNA binding	GO:0043392	3	8.342e-04	1.907e-03
219	protein kinase B signaling cascade	GO:0043491	3	9.378e-04	2.077e-03
220	regulation of immune response	GO:0050776	5	1.015e-03	2.204e-03
221	response to wounding	GO:0009611	4	1.056e-03	2.277e-03
222	regulation of growth	GO:0040008	4	1.124e-03	2.378e-03
223	positive regulation of fatty acid beta-oxidation	GO:0032000	2	1.137e-03	2.394e-03
224	negative regulation of interleukin-12 production	GO:0032695	2	1.137e-03	2.394e-03
225	positive regulation of immunoglobulin secretion	GO:0051024	2	1.137e-03	2.394e-03
226	regulation of neuron projection development	GO:0010975	2	1.137e-03	2.394e-03
227	negative regulation of neuroblast proliferation	GO:0007406	2	1.137e-03	2.394e-03
228	endothelial cell chemotaxis	GO:0035767	2	1.137e-03	2.394e-03
229	negative regulation of cholesterol storage	GO:0010887	2	1.137e-03	2.394e-03
230	stem cell development	GO:0048864	2	1.137e-03	2.394e-03
231	platelet dense granule organization	GO:0060155	2	1.137e-03	2.394e-03
232	response to molecule of bacterial origin	GO:0002237	2	1.137e-03	2.394e-03
233	negative regulation of calcium ion transport	GO:0051926	2	1.137e-03	2.394e-03
234	negative regulation of epithelial cell proliferation involved in prostate gland development	GO:0060770	2	1.137e-03	2.394e-03
235	fatty acid catabolic process	GO:0009062	2	1.137e-03	2.394e-03
236	negative regulation of release of cytochrome c from mitochondria	GO:0090201	2	1.137e-03	2.394e-03
237	negative regulation of protein phosphorylation	GO:0001933	3	1.169e-03	2.448e-03
238	T cell differentiation in thymus	GO:0033077	3	1.169e-03	2.448e-03
239	cell maturation	GO:0048469	3	1.297e-03	2.646e-03
240	cell death	GO:0008219	6	1.301e-03	2.655e-03
241	transforming growth factor beta receptor signaling pathway	GO:0007179	4	1.345e-03	2.719e-03
242	hemopoiesis	GO:0030097	4	1.345e-03	2.719e-03
243	canonical Wnt receptor signaling pathway	GO:0060070	4	1.425e-03	2.843e-03
244	wound healing	GO:0042060	4	1.425e-03	2.843e-03
245	defense response to Gram-positive bacterium	GO:0050830	3	1.433e-03	2.854e-03
246	response to laminar fluid shear stress	GO:0034616	2	1.508e-03	2.970e-03
247	intermediate filament organization	GO:0045109	2	1.508e-03	2.970e-03
248	branching involved in embryonic placenta morphogenesis	GO:0060670	2	1.508e-03	2.970e-03
249	positive regulation of MHC class II biosynthetic process	GO:0045348	2	1.508e-03	2.970e-03
250	regulation of cell growth	GO:0001558	4	1.508e-03	2.970e-03
251	ossification	GO:0001503	4	1.508e-03	2.970e-03
252	prostate gland development	GO:0030850	2	1.508e-03	2.970e-03
253	positive regulation of acute inflammatory response	GO:0002675	2	1.508e-03	2.970e-03
254	enzyme linked receptor protein signaling pathway	GO:0007167	2	1.508e-03	2.970e-03
255	positive regulation of protein import into nucleus	GO:0042307	2	1.508e-03	2.970e-03
256	S phase of mitotic cell cycle	GO:0000084	5	1.541e-03	3.021e-03
257	positive regulation of sequence-specific DNA binding transcription factor activity	GO:0051091	4	1.595e-03	3.096e-03
258	cellular response to hormone stimulus	GO:0032870	3	1.731e-03	3.293e-03
259	response to interleukin-1	GO:0070555	3	1.731e-03	3.293e-03
260	metabolic process	GO:0008152	7	1.925e-03	3.571e-03
261	defense response to protozoan	GO:0042832	2	1.930e-03	3.576e-03
262	positive regulation of nitric-oxide synthase biosynthetic process	GO:0051770	2	1.930e-03	3.576e-03
263	lymphocyte chemotaxis	GO:0048247	2	1.930e-03	3.576e-03
264	negative regulation of nitric oxide biosynthetic process	GO:0045019	2	1.930e-03	3.576e-03
265	response to caffeine	GO:0031000	2	1.930e-03	3.576e-03
266	negative regulation of transcription by competitive promoter binding	GO:0010944	2	1.930e-03	3.576e-03
267	replicative senescence	GO:0090399	2	1.930e-03	3.576e-03
268	negative regulation of cell-cell adhesion	GO:0022408	2	1.930e-03	3.576e-03
269	negative regulation of immune response	GO:0050777	2	1.930e-03	3.576e-03
270	prostate gland epithelium morphogenesis	GO:0060740	2	1.930e-03	3.576e-03
271	3'-UTR-mediated mRNA stabilization	GO:0070935	2	1.930e-03	3.576e-03
272	fibroblast growth factor receptor signaling pathway	GO:0008543	5	1.939e-03	3.590e-03
273	lactation	GO:0007595	3	2.066e-03	3.771e-03
274	activation of cysteine-type endopeptidase activity involved in apoptotic process	GO:0006919	4	2.080e-03	3.788e-03
275	gene expression	GO:0010467	12	2.112e-03	3.832e-03
276	cellular response to organic cyclic compound	GO:0071407	3	2.248e-03	4.024e-03
277	regulation of mitochondrial membrane potential	GO:0051881	2	2.401e-03	4.218e-03
278	negative regulation of androgen receptor signaling pathway	GO:0060766	2	2.401e-03	4.218e-03
279	branching involved in salivary gland morphogenesis	GO:0060445	2	2.401e-03	4.218e-03
280	cellular homeostasis	GO:0019725	2	2.401e-03	4.218e-03
281	negative regulation of blood vessel endothelial cell migration	GO:0043537	2	2.401e-03	4.218e-03
282	negative thymic T cell selection	GO:0045060	2	2.401e-03	4.218e-03
283	cell migration involved in sprouting angiogenesis	GO:0002042	2	2.401e-03	4.218e-03
284	organ induction	GO:0001759	2	2.401e-03	4.218e-03
285	negative regulation of appetite	GO:0032099	2	2.401e-03	4.218e-03
286	neural crest cell migration	GO:0001755	3	2.439e-03	4.272e-03
287	interspecies interaction between organisms	GO:0044419	8	2.540e-03	4.402e-03
288	embryonic limb morphogenesis	GO:0030326	3	2.639e-03	4.541e-03
289	phosphorylation	GO:0016310	3	2.639e-03	4.541e-03
290	fat cell differentiation	GO:0045444	3	2.639e-03	4.541e-03
291	lipoprotein metabolic process	GO:0042157	3	2.850e-03	4.829e-03
292	epidermis development	GO:0008544	4	2.918e-03	4.921e-03
293	anion transport	GO:0006820	2	2.920e-03	4.922e-03
294	negative regulation of B cell proliferation	GO:0030889	2	2.920e-03	4.922e-03
295	regulation of sodium ion transport	GO:0002028	2	2.920e-03	4.922e-03
296	macrophage differentiation	GO:0030225	2	2.920e-03	4.922e-03
297	regulation of ERK1 and ERK2 cascade	GO:0070372	2	2.920e-03	4.922e-03
298	macrophage chemotaxis	GO:0048246	2	2.920e-03	4.922e-03
299	positive regulation of nitric-oxide synthase activity	GO:0051000	2	2.920e-03	4.922e-03
300	epidermal growth factor receptor signaling pathway	GO:0007173	5	2.955e-03	4.967e-03
301	positive regulation of T cell proliferation	GO:0042102	3	3.071e-03	5.125e-03
302	regulation of cell adhesion	GO:0030155	3	3.302e-03	5.428e-03
303	response to hydrogen peroxide	GO:0042542	3	3.302e-03	5.428e-03
304	Leydig cell differentiation	GO:0033327	2	3.486e-03	5.644e-03
305	surfactant homeostasis	GO:0043129	2	3.486e-03	5.644e-03
306	elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger	GO:0051482	2	3.486e-03	5.644e-03
307	positive regulation of peptidyl-threonine phosphorylation	GO:0010800	2	3.486e-03	5.644e-03
308	response to fatty acid	GO:0070542	2	3.486e-03	5.644e-03
309	labyrinthine layer blood vessel development	GO:0060716	2	3.486e-03	5.644e-03
310	hypothalamus development	GO:0021854	2	3.486e-03	5.644e-03
311	endothelial cell proliferation	GO:0001935	2	3.486e-03	5.644e-03
312	positive regulation of cellular protein metabolic process	GO:0032270	2	3.486e-03	5.644e-03
313	positive regulation of cellular component movement	GO:0051272	2	3.486e-03	5.644e-03
314	positive regulation of smooth muscle contraction	GO:0045987	2	3.486e-03	5.644e-03
315	response to ionizing radiation	GO:0010212	3	4.057e-03	6.381e-03
316	intracellular signal transduction	GO:0035556	7	4.084e-03	6.419e-03
317	B cell proliferation	GO:0042100	2	4.100e-03	6.430e-03
318	monocyte chemotaxis	GO:0002548	2	4.100e-03	6.430e-03
319	androgen metabolic process	GO:0008209	2	4.100e-03	6.430e-03
320	ventricular septum development	GO:0003281	2	4.100e-03	6.430e-03
321	mammary gland epithelial cell differentiation	GO:0060644	2	4.100e-03	6.430e-03
322	positive regulation of osteoblast differentiation	GO:0045669	3	4.331e-03	6.718e-03
323	steroid hormone mediated signaling pathway	GO:0043401	2	4.760e-03	7.237e-03
324	response to growth factor stimulus	GO:0070848	2	4.760e-03	7.237e-03
325	response to iron ion	GO:0010039	2	4.760e-03	7.237e-03
326	negative regulation of ossification	GO:0030279	2	4.760e-03	7.237e-03
327	response to pH	GO:0009268	2	4.760e-03	7.237e-03
328	cellular response to extracellular stimulus	GO:0031668	2	4.760e-03	7.237e-03
329	cellular response to vascular endothelial growth factor stimulus	GO:0035924	2	4.760e-03	7.237e-03
330	cellular response to retinoic acid	GO:0071300	3	4.910e-03	7.427e-03
331	heart development	GO:0007507	5	4.984e-03	7.512e-03
332	multicellular organismal development	GO:0007275	15	5.274e-03	7.870e-03
333	defense response to bacterium	GO:0042742	4	5.433e-03	8.064e-03
334	positive regulation of chemokine production	GO:0032722	2	5.466e-03	8.103e-03
335	defense response to Gram-negative bacterium	GO:0050829	2	5.466e-03	8.103e-03
336	digestive tract morphogenesis	GO:0048546	2	5.466e-03	8.103e-03
337	cellular response to glucose stimulus	GO:0071333	2	5.466e-03	8.103e-03
338	positive regulation of cell cycle arrest	GO:0071158	2	5.466e-03	8.103e-03
339	induction of apoptosis via death domain receptors	GO:0008625	2	5.466e-03	8.103e-03
340	negative regulation of protein kinase activity	GO:0006469	3	5.534e-03	8.168e-03
341	proton transport	GO:0015992	3	5.863e-03	8.580e-03
342	negative regulation of gene expression	GO:0010629	3	5.863e-03	8.580e-03
343	cell growth	GO:0016049	3	6.204e-03	9.001e-03
344	muscle cell homeostasis	GO:0046716	2	6.216e-03	9.001e-03
345	positive regulation of tyrosine phosphorylation of Stat5 protein	GO:0042523	2	6.216e-03	9.001e-03
346	positive regulation of JAK-STAT cascade	GO:0046427	2	6.216e-03	9.001e-03
347	neural tube closure	GO:0001843	3	6.556e-03	9.398e-03
348	transcription from RNA polymerase II promoter	GO:0006366	7	6.706e-03	9.582e-03
349	response to vitamin D	GO:0033280	2	7.010e-03	9.940e-03
350	establishment of cell polarity	GO:0030010	2	7.010e-03	9.940e-03
351	DNA methylation	GO:0006306	2	7.010e-03	9.940e-03
352	nitric oxide metabolic process	GO:0046209	2	7.010e-03	9.940e-03
353	activation of NF-kappaB-inducing kinase activity	GO:0007250	2	7.010e-03	9.940e-03
354	homeostasis of number of cells within a tissue	GO:0048873	2	7.010e-03	9.940e-03
355	negative regulation of cyclin-dependent protein kinase activity	GO:0045736	2	7.010e-03	9.940e-03
356	vasculogenesis	GO:0001570	3	7.295e-03	1.028e-02
357	MAPK cascade	GO:0000165	3	7.295e-03	1.028e-02
358	response to calcium ion	GO:0051592	3	7.295e-03	1.028e-02
359	cell migration	GO:0016477	4	7.482e-03	1.048e-02
360	protein localization	GO:0008104	3	7.682e-03	1.074e-02
361	protein dephosphorylation	GO:0006470	4	7.737e-03	1.080e-02
362	reverse cholesterol transport	GO:0043691	2	7.848e-03	1.093e-02
363	neuron fate commitment	GO:0048663	2	7.848e-03	1.093e-02
364	regulation of sensory perception of pain	GO:0051930	2	7.848e-03	1.093e-02
365	response to light stimulus	GO:0009416	2	7.848e-03	1.093e-02
366	endothelial cell migration	GO:0043542	2	7.848e-03	1.093e-02
367	positive regulation of epithelial to mesenchymal transition	GO:0010718	2	7.848e-03	1.093e-02
368	positive regulation of branching involved in ureteric bud morphogenesis	GO:0090190	2	7.848e-03	1.093e-02
369	chromosome organization	GO:0051276	2	7.848e-03	1.093e-02
370	induction of apoptosis by extracellular signals	GO:0008624	4	8.264e-03	1.135e-02
371	cytokinesis	GO:0000910	3	8.493e-03	1.163e-02
372	O-glycan processing	GO:0016266	3	8.493e-03	1.163e-02
373	leukocyte migration	GO:0050900	4	8.536e-03	1.167e-02
374	response to hyperoxia	GO:0055093	2	8.729e-03	1.190e-02
375	cellular response to ionizing radiation	GO:0071479	2	8.729e-03	1.190e-02
376	cholesterol metabolic process	GO:0008203	3	8.917e-03	1.212e-02
377	cell adhesion	GO:0007155	10	9.085e-03	1.231e-02
378	small molecule metabolic process	GO:0044281	15	9.191e-03	1.244e-02
379	positive regulation of cell growth	GO:0030307	3	9.352e-03	1.264e-02
380	peptidyl-tyrosine dephosphorylation	GO:0035335	3	9.352e-03	1.264e-02
381	negative regulation of fibroblast proliferation	GO:0048147	2	9.651e-03	1.298e-02
382	neuron apoptosis	GO:0051402	2	9.651e-03	1.298e-02
383	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis	GO:0042771	2	9.651e-03	1.298e-02
384	DNA damage response, signal transduction resulting in induction of apoptosis	GO:0008630	2	9.651e-03	1.298e-02
385	response to inorganic substance	GO:0010035	2	9.651e-03	1.298e-02
386	positive regulation of cytokine secretion	GO:0050715	2	1.062e-02	1.406e-02
387	positive regulation of calcium ion transport	GO:0051928	2	1.062e-02	1.406e-02
388	pituitary gland development	GO:0021983	2	1.062e-02	1.406e-02
389	negative regulation of insulin receptor signaling pathway	GO:0046627	2	1.062e-02	1.406e-02
390	negative regulation of tumor necrosis factor production	GO:0032720	2	1.162e-02	1.518e-02
391	cellular response to calcium ion	GO:0071277	2	1.162e-02	1.518e-02
392	cellular response to drug	GO:0035690	2	1.162e-02	1.518e-02
393	eating behavior	GO:0042755	2	1.162e-02	1.518e-02
394	spleen development	GO:0048536	2	1.162e-02	1.518e-02
395	negative regulation of smooth muscle cell proliferation	GO:0048662	2	1.162e-02	1.518e-02
396	negative regulation of cell migration	GO:0030336	3	1.172e-02	1.529e-02
397	activation of signaling protein activity involved in unfolded protein response	GO:0006987	3	1.172e-02	1.529e-02
398	transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	3	1.172e-02	1.529e-02
399	positive regulation of cell-substrate adhesion	GO:0010811	2	1.267e-02	1.635e-02
400	embryonic forelimb morphogenesis	GO:0035115	2	1.267e-02	1.635e-02
401	response to testosterone stimulus	GO:0033574	2	1.267e-02	1.635e-02
402	cellular calcium ion homeostasis	GO:0006874	3	1.275e-02	1.644e-02
403	regulation of sequence-specific DNA binding transcription factor activity	GO:0051090	3	1.275e-02	1.644e-02
404	peptidyl-threonine phosphorylation	GO:0018107	2	1.375e-02	1.755e-02
405	epithelial to mesenchymal transition	GO:0001837	2	1.375e-02	1.755e-02
406	steroid biosynthetic process	GO:0006694	2	1.375e-02	1.755e-02
407	hair follicle morphogenesis	GO:0031069	2	1.487e-02	1.875e-02
408	vasculature development	GO:0001944	2	1.487e-02	1.875e-02
409	adrenal gland development	GO:0030325	2	1.487e-02	1.875e-02
410	embryonic hindlimb morphogenesis	GO:0035116	2	1.487e-02	1.875e-02
411	face morphogenesis	GO:0060325	2	1.487e-02	1.875e-02
412	extracellular matrix organization	GO:0030198	3	1.496e-02	1.885e-02
413	negative regulation of fat cell differentiation	GO:0045599	2	1.603e-02	2.005e-02
414	germ cell development	GO:0007281	2	1.603e-02	2.005e-02
415	Ras protein signal transduction	GO:0007265	3	1.615e-02	2.018e-02
416	liver development	GO:0001889	3	1.615e-02	2.018e-02
417	cell cycle checkpoint	GO:0000075	4	1.648e-02	2.053e-02
418	branching morphogenesis of a tube	GO:0048754	2	1.723e-02	2.133e-02
419	tumor necrosis factor-mediated signaling pathway	GO:0033209	2	1.723e-02	2.133e-02
420	developmental growth	GO:0048589	2	1.723e-02	2.133e-02
421	phosphatidylinositol-mediated signaling	GO:0048015	3	1.802e-02	2.219e-02
422	cell-cell adhesion	GO:0016337	3	1.802e-02	2.219e-02
423	blood vessel remodeling	GO:0001974	2	1.847e-02	2.268e-02
424	regulation of protein localization	GO:0032880	2	1.847e-02	2.268e-02
425	erythrocyte differentiation	GO:0030218	2	1.847e-02	2.268e-02
426	neural tube development	GO:0021915	2	1.847e-02	2.268e-02
427	response to axon injury	GO:0048678	2	1.847e-02	2.268e-02
428	oxidation-reduction process	GO:0055114	4	1.867e-02	2.286e-02
429	toll-like receptor 4 signaling pathway	GO:0034142	3	1.934e-02	2.357e-02
430	patterning of blood vessels	GO:0001569	2	1.974e-02	2.401e-02
431	negative regulation of osteoblast differentiation	GO:0045668	2	1.974e-02	2.401e-02
432	Toll signaling pathway	GO:0008063	3	2.001e-02	2.429e-02
433	insulin receptor signaling pathway	GO:0008286	4	2.054e-02	2.484e-02
434	metanephros development	GO:0001656	2	2.105e-02	2.539e-02
435	protein polymerization	GO:0051258	2	2.105e-02	2.539e-02
436	positive regulation of interleukin-6 production	GO:0032755	2	2.105e-02	2.539e-02
437	response to activity	GO:0014823	2	2.105e-02	2.539e-02
438	negative regulation of Wnt receptor signaling pathway	GO:0030178	2	2.105e-02	2.539e-02
439	lipid metabolic process	GO:0006629	5	2.129e-02	2.564e-02
440	thymus development	GO:0048538	2	2.239e-02	2.683e-02
441	actin filament organization	GO:0007015	2	2.239e-02	2.683e-02
442	behavior	GO:0007610	2	2.377e-02	2.829e-02
443	mesoderm development	GO:0007498	2	2.377e-02	2.829e-02
444	positive regulation of cAMP biosynthetic process	GO:0030819	2	2.377e-02	2.829e-02
445	response to nutrient	GO:0007584	3	2.511e-02	2.971e-02
446	growth	GO:0040007	2	2.518e-02	2.979e-02
447	positive regulation of DNA replication	GO:0045740	2	2.662e-02	3.137e-02
448	inhibition of adenylate cyclase activity by G-protein signaling pathway	GO:0007193	2	2.662e-02	3.137e-02
449	steroid metabolic process	GO:0008202	3	2.914e-02	3.399e-02
450	circadian rhythm	GO:0007623	2	2.961e-02	3.449e-02
451	bile acid metabolic process	GO:0008206	2	2.961e-02	3.449e-02
452	activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway	GO:0007205	2	2.961e-02	3.449e-02
453	ureteric bud development	GO:0001657	2	3.115e-02	3.609e-02
454	mitotic cell cycle	GO:0000278	6	3.250e-02	3.747e-02
455	electron transport chain	GO:0022900	2	3.272e-02	3.770e-02
456	embryonic digit morphogenesis	GO:0042733	2	3.272e-02	3.770e-02
457	positive regulation of inflammatory response	GO:0050729	2	3.272e-02	3.770e-02
458	spermatogenesis	GO:0007283	6	3.336e-02	3.838e-02
459	nervous system development	GO:0007399	7	3.390e-02	3.894e-02
460	endocrine pancreas development	GO:0031018	2	3.433e-02	3.938e-02
461	anatomical structure morphogenesis	GO:0009653	3	3.439e-02	3.944e-02
462	heart looping	GO:0001947	2	3.596e-02	4.109e-02
463	G-protein signaling, coupled to cyclic nucleotide second messenger	GO:0007187	2	3.596e-02	4.109e-02
464	activation of MAPKK activity	GO:0000186	2	3.762e-02	4.280e-02
465	response to organic substance	GO:0010033	2	3.931e-02	4.455e-02
466	T cell activation	GO:0042110	2	3.931e-02	4.455e-02
467	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	GO:0035872	2	3.931e-02	4.455e-02
468	skin development	GO:0043588	2	3.931e-02	4.455e-02
469	regulation of cell migration	GO:0030334	2	4.103e-02	4.632e-02
470	energy reserve metabolic process	GO:0006112	3	4.211e-02	4.745e-02
471	response to retinoic acid	GO:0032526	2	4.278e-02	4.814e-02
472	cell cycle	GO:0007049	7	4.389e-02	4.925e-02